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New England Journal of Medicine
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New England Journal of Medicine - DOI: 10.1056/NEJMOA1812389
Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes

Declare–Timi Investigators ·

Medicine
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New England Journal of Medicine - DOI: 10.1056/NEJMoa1901118
Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.

Mansoor Husain · Andreas L Birkenfeld · Morten Donsmark · Kathleen Dungan · Freddy G Eliaschewitz · Denise R Franco · Ole K Jeppesen · Ildiko Lingvay · Ofri Mosenzon · Sue D Pedersen · Cees J Tack · Mette Thomsen · Tina Vilsbøll · Mark L Warren · Stephen C Bain ·

Medicine
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New England Journal of Medicine - DOI: 10.1056/NEJMoa1806802
Intensive Glucose Control in Patients with Type 2 Diabetes - 15-Year Follow-up.

Peter D Reaven · Nicholas V Emanuele · Wyndy L Wiitala · Gideon D Bahn · Domenic J Reda · Madeline McCarren · William C Duckworth · Rodney A Hayward ·

Medicine
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New England Journal of Medicine - DOI: 10.1056/NEJMoa1813446
C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia.

Ravi Savarirayan · Melita Irving · Carlos A Bacino · Bret Bostwick · Joel Charrow · Valerie Cormier-Daire · Kim-Hanh Le Quan Sang · Patricia Dickson · Paul Harmatz · John Phillips · Natalie Owen · Anu Cherukuri · Kala Jayaram · George S Jeha · Kevin Larimore · Ming-Liang Chan · Alice Huntsman Labed · Jonathan Day · Julie Hoover-Fong ·

Medicine
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New England Journal of Medicine - DOI: 10.1056/NEJMc1905039
Phenotype in an Infant with SOD1 Homozygous Truncating Mutation.

Peter M Andersen · Ulrika Nordström · Konstantinos Tsiakas · Jessika Johannsen · Alexander E Volk · Tatjana Bierhals · Per Zetterström · Stefan L Marklund · Maja Hempel · René Santer ·

Medicine
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Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment.

Correction: Clinical utility of hyperbaric oxygen therapy in dentistry [10.4103/2045-9912.267001]


They report that antibody responses against specific commensals measured before T1D diagnosis distinguished individuals with islet autoantibodies from healthy controls in a human leukocyte antigen haplotype–dependent manner.

Association of HLA-dependent islet autoimmunity with systemic antibody responses to intestinal commensal bacteria in children [10.1126/sciimmunol.aau8125]


The Expanding Phenotype Spectrum of ARVC: First described by the Italian physician and anatomist Giovanni Maria Lancisi in 1728, Arrhythmogenic right ventricular cardiomyopathy (ARVC) is recognized as a genetic heart disease with a progressive course and a high risk of sudden cardiac death (SCD).

Revisiting the Approach to Diagnosis of Arrhythmogenic Cardiomyopathy: Stick to the Arrhythmia Criterion! [10.1161/CIRCGEN.119.002665]


AIM: The evaluation of the outcome of the operatively treated meningiomas in relation with the Karnofsky performance score, survival, recurrence, type of the surgical excision, histological type, mitotic count (MC), localisation and volume of the lesion METHODS: In this article 40 operatively treated patients are reviewed for the outcome of the operation about the Karnofsky performance score, survival, recurrence, type of the surgical excision, histological type, mitotic count (MC), localisation and volume of the lesion.

Surgical Treatment of Meningiomas - Outcome Associated With Type of Resection, Recurrence, Karnofsky Performance Score, Mitotic Count. [10.3889/OAMJMS.2019.032]


We prove the Angehrn–Siu type effective freeness and effective point separation for quasi-log canonical pairs.

Angehrn–Siu type effective basepoint freeness for quasi-log canonical pairs [10.1215/21562261-2019-0014]


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