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New England Journal of Medicine
Research Hotspot & Journal Scope - Lipid


New England Journal of Medicine - DOI: 10.1056/NEJMra1806939
Lipid Management for the Prevention of Atherosclerotic Cardiovascular Disease.

Erin D Michos · John W McEvoy · Roger S Blumenthal ·

Medicine
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New England Journal of Medicine - DOI: 10.1056/NEJMoa1815111
Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy.

Marin L Gantner · Kevin Eade · Martina Wallace · Michal K Handzlik · Regis Fallon · Jennifer Trombley · Roberto Bonelli · Sarah Giles · Sarah Harkins-Perry · Tjebo F C Heeren · Lydia Sauer · Yoichiro Ideguchi · Michelle Baldini · Lea Scheppke · Michael I Dorrell · Maki Kitano · Barbara J Hart · Carolyn Cai · Takayuki Nagasaki · Mehmet G Badur · Mali Okada · Sasha M Woods · Catherine Egan · Mark Gillies · Robyn Guymer · Florian Eichler · Melanie Bahlo · Marcus Fruttiger · Rando Allikmets · Paul S Bernstein · Christian M Metallo · Martin Friedlander ·

Medicine
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One of the major risk factors of ASCVD is dyslipidemia and all the available guidelines suggest the importance of strategies for lipid control in a remarkable proportion of the general population.

Current pharmacotherapeutic options for primary dyslipidemia in adults [10.1080/14656566.2019.1604687]


Therefore, TSB and TSF relieve lipid accumulation by attenuating lipogenic protein expression, activating the AMPK pathway, and upregulating the autophagic flux to enhance lipid metabolism.

Polyphenol-Rich Extracts from Toona sinensis Bark and Fruit Ameliorate Free Fatty Acid-Induced Lipogenesis through AMPK and LC3 Pathways [10.3390/jcm8101664]


Using examples on different phospholipid classes, including phosphatidylinositol-4,5-bisphosphate, phosphatidylserine, phosphatidylcholine, and phosphatidic acid, we review how spatio-temporal lipid patterns arise at the organismal level and what are their downstream consequences on plant development.

Phospholipids across scales: lipid patterns and plant development. [10.1016/j.pbi.2019.08.007]


Studies suggest that similar fat accumulation in a given population might result in different levels of dyslipidemia risk among individuals; for example, despite similar or leaner body composition compared with Caucasians, Asians of Korean descent experience a higher prevalence of dyslipidemia.

A genome-wide search for gene-by-obesity interaction loci of dyslipidemia in Koreans shows diverse genetic risk alleles[S] [10.1194/jlr.P119000226]


We first verified that both pH-induced hydrolysis and light treatment were able to cleave Fa-ONB lipid.

A multifunctional lipid incorporating active targeting and dual-control release capabilities for precision drug delivery. [10.1021/acsami.9b14470]


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