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Pancreas
Research Hotspot & Journal Scope - Pancreatic


Pancreas - DOI: 10.1097/MPA.0000000000001231
Chemotherapy Versus Chemoradiation as Preoperative Therapy for Resectable Pancreatic Ductal Adenocarcinoma: A Propensity Score Adjusted Analysis

Jordan M Cloyd · Hsiang-Chun Chen · Xuemei Wang · Ching-Wei D Tzeng · Michael P Kim · Thomas A Aloia · Jean-Nicolas Vauthey · Jeffrey E Lee · Matthew H G Katz ·

Medicine
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Pancreas - DOI: 10.1097/MPA.0000000000001230
Global Patterns and Trends in Pancreatic Cancer Incidence: Age, Period, and Birth Cohort Analysis

Ganfeng Luo · Yanting Zhang · Pi Guo · Huanlin Ji · Yuejiao Xiao · Ke Li ·

Medicine Biology
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Pancreas - DOI: 10.1097/MPA.0000000000001226
Statin Use and Risk of Pancreatic Cancer: An Updated Meta-analysis of 26 Studies

Yun Zhang · Mingming Liang · Chenyu Sun · Guangbo Qu · Tingting Shi · Min Min · Yile Wu · Yehuan Sun ·

Medicine
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Pancreas - DOI: 10.1097/MPA.0000000000001249
Direct Interactions With Cancer-Associated Fibroblasts Lead to Enhanced Pancreatic Cancer Stem Cell Function

Asma Begum · Ross H McMillan · Yu-Tai Chang · Vesselin R Penchev · N V Rajeshkumar · Anirban Maitra · Michael G Goggins · James R Eshelman · Christopher L Wolfgang · Zeshaan A Rasheed · William Matsui ·

Medicine
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Pancreas - DOI: 10.1097/MPA.0000000000001195
Tenascin C, Fibronectin, and Tumor-Stroma Ratio in Pancreatic Ductal Adenocarcinoma

Joni Leppänen · Ville Lindholm · Joel Isohookana · Kirsi-Maria Haapasaari · Peeter Karihtala · Petri P. Lehenkari · Juha Saarnio · Joonas H. Kauppila · Tuomo J. Karttunen · Olli Helminen · Heikki Huhta ·

Biology Medicine
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These findings suggest that piperine treatment ameliorates pancreatic fibrosis by inhibiting TGF-β/SMAD2/3 signaling during CP.

Piperine ameliorates the severity of fibrosis via inhibition of TGF-β/SMAD signaling in a mouse model of chronic pancreatitis [10.3892/mmr.2019.10635]


This work shows a nanoparticle that has been functionalized with a pancreatic cancer-specific targeting ligand and exhibits specific particle release in pancreatic malignant environment (pH 6.

Abstract 1937: pH-responsive tumor-targeted mesoporous silica nanoparticle for the identification of pancreatic cancer using optoacoustic tomography [10.1158/1538-7445.AM2019-1937]


2 When analgesic therapy fails, invasive treatments including endoscopic pancreatic duct clearance (with or without extracorporeal shock wave lithotripsy (ESWL)) or pancreatic duct stenting and surgery (resection and/or ductal decompression) are used.

Controversies on the endoscopic and surgical management of pain in patients with chronic pancreatitis: pros and cons! [10.1136/gutjnl-2019-318742]


In this article, we elucidate protocols for preparing a pancreatic tissue-derived decellularized extracellular matrix (pdECM) bioink to provide a beneficial microenvironment that can increase glucose sensitivity of pancreatic islets, followed by describing the processes for generating 3D pancreatic tissue constructs using a microextrusion-based bioprinting technique.

Pancreatic Tissue-Derived Extracellular Matrix Bioink for Printing 3D Cell-Laden Pancreatic Tissue Constructs. [10.3791/60434]


Here we review the literature on surgical and locoregional approaches including radiofrequency ablation, irreversible electroporation, and stereotactic body radiation, and focus on patients with hepatic oligometastatic pancreatic cancer.

Surgery or Locoregional Approaches for Hepatic Oligometastatic Pancreatic Cancer: Myth, Hope, or Reality? [10.3390/cancers11081095]


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