Pancreas

Research Hotspot & Journal Scope - Metastasis

The efficacy of tumour starvation therapy is limited by lack of persistent tumour suppression, tumour metastasis and recurrence.

In addition, the Notch1/Slug pathway is found to mediate an antimetastasis role of HO-1 in mouse mammary carcinoma.

However, emerging data from some clinical HCC patients indicates that sorafenib alone has only moderate antitumor efficacy, and could not inhibit metastasis and progression of disease.

This case is presented because of the unusual and rare presentation in the form of distant subcutaneous metastasis.

8%) developed recurrent diseases, 12 developed distant or multiple metastasis, and 3 developed locoregional recurrence.