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Research Hotspot & Journal Scope - Clinical

Pancreas - DOI: 10.1097/MPA.0000000000001203
Emerging Evidence for the Clinical Relevance of Pancreatic Cancer Exosomes

Roxanne L Massoumi · O Joe Hines · Guido Eibl · Jonathan C King ·

Pancreas - DOI: 10.1097/MPA.0000000000001439
A Clinical Feasible Method for Computed Tomography-Based Assessment of Sarcopenia in Patients With Chronic Pancreatitis

Imanta Ozola-Zālīte · Jens Brøndum Frøkjær · Esben Bolvig Mark · Tomas Gudauskas · Linas Gudauskas · Milda Dedelaite · Edita Bieliuniene · Povilas Ignatavicius · Aldis Pukitis · Asbjørn Mohr Drewes · Søren Schou Olesen ·

Pancreas - DOI: 10.1097/MPA.0000000000001189
The Molecular and Clinical Landscape of Pancreatic Neuroendocrine Tumors

Bhavina D.O. Batukbhai · Ana De Jesus-Acosta ·

Pancreas - DOI: 10.1097/MPA.0000000000001248
Expression and Clinical Significance of Protein Kinase RNA–Like Endoplasmic Reticulum Kinase and Phosphorylated Eukaryotic Initiation Factor 2&agr; in Pancreatic Ductal Adenocarcinoma

Eric M Wang · Hironari Akasaka · Jun Zhao · Gauri R Varadhachary · Jeffrey E Lee · Anirban Maitra · Jason B Fleming · Mien-Chie Hung · Huamin Wang · Matthew H G Katz ·

Biology Medicine
Pancreas - DOI: 10.1097/MPA.0000000000001375
18F-Fluorodeoxyglucose Positron Emission Tomography Predicts Treatment Efficacy and Clinical Outcome for Patients With Pancreatic Carcinoma

Li Wang · Ping Dong · Guohua Shen · Shengzhong Hou · Yi Zhang · Xubao Liu · Bole Tian ·

Medicine Biology

It was therefore easy for us to focus the 2018 ISOPT Clinical retinal discussions on delivery systems, drug efficacy and classic questions such as: have we reached the unbreakable glass ceiling of efficacy in wet age-related macular degeneration (AMD)? Can we aim our target to achieve an even higher effect? Can it be reached by new chemical/biological entities or would delivery system allow us to reach higher points of efficacy? The discussion also addressed the issue of dry AMD and the glorious parade of failures so far, and how do we measure success and failure via relevant endpoints.

ISOPT Clinical Hot Topic Panel Discussion on Medical Treatment of Retinal Diseases. [10.1089/jop.2019.0073]

Conclusion: This phase 0 imaging clinical trial provides evidence that 18F-FdCyd administered in conjunction with tetrahydrouridine yields acceptable individual organ and whole-body effective doses, as well as modest tumor-to-background ratios that potentially enable tumor visualization.

Biodistribution, Tumor Detection, and Radiation Dosimetry of 18F-5-Fluoro-2′-Deoxycytidine with Tetrahydrouridine in Solid Tumors [10.2967/jnumed.118.216994]

METHODS: With external validation dataset (43 disorders; 40,435 clinical images from 10,450 patients; January 1, 2008 - March 31, 2019), we compared the prediction of algorithm with the clinical diagnosis of 65 attending physicians at the time of biopsy request.

Retrospective Assessment of Deep Neural Networks for Skin Tumor Diagnosis [10.1101/2019.12.12.19014647]

Sodium propionate (NaP) most potently inhibited the growth of MRSA and multidrug-resistant clinical isolates.

Propionate Ameliorates Staphylococcus aureus Skin Infection by Attenuating Bacterial Growth [10.3389/fmicb.2019.01363]

This clinical reality is an open challenge to the oncologist because of those neoplasms which elaborate neuroendocrine differentiation (NED).

Neuroendocrine differentiation in castration resistant prostate cancer. Nuclear medicine radiopharmaceuticals and imaging techniques: A narrative review. [10.1016/J.CRITREVONC.2019.03.005]

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