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PLoS ONE
Research Hotspot & Journal Scope - vitro


PLoS ONE - DOI: 10.1371/journal.pone.0210530
Determinants of corrosion resistance of Ti-6Al-4V alloy dental implants in an In Vitro model of peri-implant inflammation

Larissa O Berbel · Everson do P Banczek · Ioannis K Karoussis · Georgios A Kotsakis · Isolda Costa ·

Materials Science Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0208611
Purification, characterization and in vitro and in vivo immune enhancement of polysaccharides from mulberry leaves

Xiaolan Chen · Zhicun Sheng · Shulei Qiu · Haifeng Yang · Jiping Jia · Jing Wang · Chunmao Jiang ·

Chemistry Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0210508
In vitro and in vivo properties of the bovine antimicrobial peptide, Bactenecin 5

R L Price · L Bugeon · S Mostowy · C Makendi · B W Wren · H D Williams · S J Willcocks ·

Biology Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0218740
Hyaluronic Acid (HA), Platelet-Rich Plasm and Extracorporeal Shock Wave Therapy (ESWT) promote human chondrocyte regeneration in vitro and ESWT-mediated increase of CD44 expression enhances their susceptibility to HA treatment

Mario Vetrano · Danilo Ranieri · Monica Nanni · Antonio Pavan · Florence Malisan · Maria Chiara Vulpiani · Vincenzo Visco ·

Chemistry Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0213049
Biochemical profile and in vitro biological activities of extracts from seven folk medicinal plants growing wild in southern Tunisia

Hajer Tlili · Najjaa Hanen · Abdelkerim Ben Arfa · Mohamed Neffati · Abdelbasset Boubakri · Daniela Buonocore · Maurizia Dossena · Manuela Verri · Enrico Doria ·

Biology Medicine
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The histones purified through this method can be directly assembled into chromatin through in vitro assembly reactions, providing a unique opportunity to biochemically dissect the effect of histone variants, histone modifications, and other factors in chromatin replication and assembly.

Chromatin Characterization in Xenopus laevis Cell-Free Egg Extracts and Embryos. [10.1101/pdb.prot099879]


These methods of in vitro mutagenesis have had a transforming effect on the understanding of functions of protein, transcription regulatory elements, and noncoding RNAs and are now integral to molecular biology investigations.

Methods for In Vitro Mutagenesis. [10.1101/pdb.top097733]


Here, using subcellular fractionation protocols in combination with in vitro pharmacology and proteasome activity assays, we investigated the conditions under which CaMKII and PKA regulate proteasome activity in the brains of male and female rats.

Males and Females Differ in the Subcellular and Brain Region Dependent Regulation of Proteasome Activity by CaMKII and Protein Kinase A [10.1016/j.neuroscience.2019.08.031]


We performed laparoscopic pancreatic parenchymal dissection with cavitron ultrasonic surgical aspirator (CUSA) successfully in a patient with titanium allergy.

Pure laparoscopic pancreas parenchymal dissection using CUSA for distal pancreatectomy [10.1080/13645706.2018.1479272]


High drug loading and good in vitro controlled drug release were observed with DS-OPT-SA clay and polymer combination.

Nanocomposite clay-polymer microbeads for oral controlled drug delivery: Development and, in vitro and in vivo evaluations [10.1016/J.JDDST.2019.03.001]


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