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PLoS ONE
Research Hotspot & Journal Scope - treatment


PLoS ONE - DOI: 10.1371/journal.pone.0210016
Fecal microbiota transplantation for treatment of recurrent C. difficile infection: An updated randomized controlled trial meta-analysis

Wenjia Hui · Ting Li · Weidong Liu · Chunyan Zhou · Feng Gao ·

Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0217536
Challenges and caveats of a multi-center retrospective radiomics study: an example of early treatment response assessment for NSCLC patients using FDG-PET/CT radiomics

Janna E van Timmeren · Sara Carvalho · Ralph T H Leijenaar · Esther G C Troost · Wouter van Elmpt · Dirk de Ruysscher · Jean-Pierre Muratet · Fabrice Denis · Tanja Schimek-Jasch · Ursula Nestle · Arthur Jochems · Henry C Woodruff · Cary Oberije · Philippe Lambin ·

Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0208506
Safety and efficacy of glecaprevir/pibrentasvir for the treatment of chronic hepatitis C in patients aged 65 years or older

Graham R Foster · Tarik Asselah · Sarah Kopecky-Bromberg · Yang Lei · Armen Asatryan · Roger Trinh · Neddie Zadeikis · Federico J Mensa ·

Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0225644
Removal efficiency of central vacuum system and protective masks to suspended particles from dental treatment

Ming-Hui Liu · Chi-Tsung Chen · Li-Chuan Chuang · Wen-Ming Lin · Gwo-Hwa Wan ·

Materials Science Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0209911
Body composition and adipokines changes after initial treatment with darunavir-ritonavir plus either raltegravir or tenofovir disoproxil fumarate-emtricitabine: A substudy of the NEAT001/ANRS143 randomised trial

Jose I Bernardino · Amanda Mocroft · Cedrick Wallet · Stéphane de Wit · Christine Katlama · Peter Reiss · Patrick W Mallon · Laura Richert · Jean-Michel Molina · Hernando Knobel · Philippe Morlat · Abdel Babiker · Anton Pozniac · Francois Raffi · Jose R Arribas ·

Medicine
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This is compared to 33% of patients(n=7) who failed vedolizumab treatment post surgery.

PTH-078 Vedolizumab post resection for Crohn’s disease: a 4 year real world experience [10.1136/GUTJNL-2019-BSGABSTRACTS.137]


Compared with no/conventional treatment, surgery was cost saving over a lifetime scenario.

Bariatric surgery is a cost‐saving treatment for obesity—A comprehensive meta‐analysis and updated systematic review of health economic evaluations of bariatric surgery [10.1111/obr.12932]


Serum IgG-Fc N-glycan structures in patients with HBV-related liver cirrhosis, who had received either telbivudine treatment or entecavir treatment for at least 48 weeks were analyzed using liquid chromatography tandem-mass spectrometry.

Telbivudine on IgG-associated hypergammaglobulinemia and TGF-β1 hyperactivity in hepatitis B virus-related liver cirrhosis [10.1371/journal.pone.0225482]


A research trial to investigate the benefits of vitamin D deficiency treatment would test this hypothesis.

Vitamin D and assisted reproductive treatment outcome: a prospective cohort study [10.1186/s12978-019-0769-7]


There are several issues and principles discussed, like the principle of independence of patents, national treatment, and minimum term of protection; all contained in the Paris Convention, TRIPs agreement and also the Patent Cooperation Treaty.

Takeda v. Rimsa. México, el Convenio de París, el ADPIC y el TCP [10.4067/s0718-34372019000300945]


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