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PLoS ONE
Research Hotspot & Journal Scope - genome


PLoS ONE - DOI: 10.1371/journal.pone.0218204
Comparative genome analysis reveals niche-specific genome expansion in Acinetobacter baumannii strains

Harshita Yakkala · Devyani Samantarrai · Michael Gribskov · Dayananda Siddavattam ·

Biology Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0210892
Comprehensive genome-wide analysis of the pear (Pyrus bretschneideri) laccase gene (PbLAC) family and functional identification of PbLAC1 involved in lignin biosynthesis

Xi Cheng · Guohui Li · Chenhui Ma · Muhammad Abdullah · Jinyun Zhang · Hai Zhao · Qing Jin · Yongping Cai · Yi Lin ·

Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0215512
The plastid genome and its implications in barcoding specific-chemotypes of the medicinal herb Pogostemon cablin in China

Caiyun Zhang · Tongjian Liu · Xun Yuan · Huirun Huang · Gang Yao · Xiaolu Mo · Xue Xue · Haifei Yan ·

Biology Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0215901
Genome-wide identification and gene expression pattern of ABC transporter gene family in Capsicum spp.

Carlos Lopez-Ortiz · Sudip Kumar Dutta · Purushothaman Natarajan · Yadira Peña-Garcia · Venkata Abburi · Thangasamy Saminathan · Padma Nimmakayala · Umesh K Reddy ·

Biology Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0223371
Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease

Chihiro Udagawa · Hidehito Horinouchi · Kouya Shiraishi · Takashi Kohno · Takuji Okusaka · Hideki Ueno · Kenji Tamura · Yuichiro Ohe · Hitoshi Zembutsu ·

Biology Medicine
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Results: Bacteria diversity by metagenome analysis was decreased in CRC group compared to control group.

Difference of colorectal cancer microbial community by metagenomics and culture-based methods. [10.1200/JCO.2019.37.4_SUPPL.489]


By using datasets of whole-genome transcriptome, the expressions of 54 co-stimulatory or co-inhibitory genes in common autoimmune diseases were analyzed using Robust rank aggregation (RRA) method.

Aberrant Expressions of Co-stimulatory and Co-inhibitory Molecules in Autoimmune Diseases [10.3389/fimmu.2019.00261]


Reference genomes are essential for metagenomic analyses and functional characterization of the human gut microbiota.

1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses [10.1038/s41587-018-0008-8]


Bronze and Iron Age genomes suggest a European-related gene flow coincided with the Philistines arrival in ancient Ashkelon.

Ancient DNA sheds light on the genetic origins of early Iron Age Philistines [10.1126/sciadv.aax0061]


Summary Recurrence and clustering of somatic mutations (hotspots) in cancer genomes may indicate positive selection and involvement in tumorigenesis.

MutSpot: detection of non-coding mutation hotspots in cancer genomes [10.1101/740944]


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