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PLoS ONE
Research Hotspot & Journal Scope - disease


PLoS ONE - DOI: 10.1371/journal.pone.0210081
Invasive pneumococcal diseases in children and adults before and after introduction of the 10-valent pneumococcal conjugate vaccine into the Austrian national immunization program

Lukas Richter · Daniela Schmid · Elisabeth Eva Kanitz · Ines Zwazl · Eva Pöllabauer · Joanna Jasinska · Heinz Burgmann · Michael Kundi · Ursula Wiedermann ·

Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0211343
Depression and anxiety in patients with different rare chronic diseases: A cross-sectional study

Natalie Uhlenbusch · Bernd Löwe · Martin Härter · Christoph Schramm · Christina Weiler-Normann · Miriam K Depping ·

Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0212922
Culture and Real-time Polymerase Chain reaction sensitivity in the diagnosis of invasive meningococcal disease: Does culture miss less severe cases?

Sara Guiducci · Maria Moriondo · Francesco Nieddu · Silvia Ricci · Elisa De Vitis · Arianna Casini · Giovanni Maria Poggi · Giuseppe Indolfi · Massimo Resti · Chiara Azzari ·

Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0215665
Epidemiological and clinical features of Kawasaki disease in Spain over 5 years and risk factors for aneurysm development. (2011-2016): KAWA-RACE study group

Elisa Fernandez-Cooke · Ana Barrios Tascón · Judith Sánchez-Manubens · Jordi Antón · Carlos Daniel Grasa Lozano · Javier Aracil Santos · Enrique Villalobos Pinto · Daniel Clemente Garulo · Beatriz Mercader Rodríguez · Matilde Bustillo Alonso · Esmeralda Nuñez Cuadros · Maria Luisa Navarro Gómez · Sara Domínguez-Rodríguez · Cristina Calvo ·

Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0221365
Amyloid-β PET—Correlation with cerebrospinal fluid biomarkers and prediction of Alzheimer´s disease diagnosis in a memory clinic

Ebba Gløersen Müller · Trine Holt Edwin · Caroline Stokke · Sigrid Stensby Navelsaker · Almira Babovic · Nenad Bogdanovic · Anne Brita Knapskog · Mona Elisabeth Revheim ·

Medicine
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Despite PC-MRI not being routinely used in clinical practice, there are several clinical studies showing its potential to support diagnosis and monitoring of renal diseases, in particular renovascular disease, chronic kidney disease and autosomal dominant polycystic kidney disease.

Phase-contrast magnetic resonance imaging to assess renal perfusion: a systematic review and statement paper [10.1007/s10334-019-00772-0]


Among fish viral diseases, betanodavirus is a significant pathogen that causes viral nervous necrosis (VNN) and can result in mass mortalities to fish culture especially at larval stages.

A review of betanodavirus vaccination as preventive strategy to viral nervous necrosis (VNN) disease in grouper [10.1007/s10499-019-00410-5]


Inherited risk for prostate cancer is associated with aggressive disease and poorer outcomes, indicating a critical need for increased genetic screening to identify disease-causing variants that can pinpoint individuals at increased risk for metastatic castration-resistant prostate cancer.

Prevalence of Germline Variants in Prostate Cancer and Implications for Current Genetic Testing Guidelines [10.1001/jamaoncol.2018.6760]


Aging is a major driver for chronic kidney disease (CKD) and the counterbalancing of aging processes holds promise to positively impact disease development and progression.

Computational Drug Screening Identifies Compounds Targeting Renal Age-associated Molecular Profiles [10.1016/j.csbj.2019.06.019]


Design: 271 patients with celiac disease participated in this transversal descriptive study and completed a series of questionnaires regarding adherence (CDAT), general self-efficacy (GSES) and specific self-efficacy (Celiac-SE) and quality of life (CD-Qol), among others.

The effect of self-efficacy expectations in the adherence to a gluten free diet in celiac disease [10.1080/08870446.2019.1675658]


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