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PLoS ONE
Research Hotspot & Journal Scope - cancer


PLoS ONE - DOI: 10.1371/journal.pone.0210077
The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma

S Di Matteo · L Nevi · D Costantini · D Overi · G Carpino · S Safarikia · F Giulitti · C Napoletano · E Manzi · A M De Rose · F Melandro · M Bragazzi · P B Berloco · F Giuliante · G Grazi · A Giorgi · V Cardinale · L Adorini · E Gaudio · D Alvaro ·

Chemistry Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0214318
Phenotype of POLE-mutated endometrial cancer

Sara Imboden · Denis Nastic · Mehran Ghaderi · Filippa Rydberg · Tilman T Rau · Michael D Mueller · Elisabeth Epstein · Joseph W Carlson ·

Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0221026
The impact of worldwide, national and sub-national severity distributions in Burden of Disease studies: A case study of cancers in Scotland

Grant Wyper · Ian Grant · Eilidh Fletcher · Gerry McCartney · Diane Stockton ·

Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0220860
CRISPR-Cas9 mediated CD133 knockout inhibits colon cancer invasion through reduced epithelial-mesenchymal transition

Wanlu Li · Mee-Yon Cho · Suji Lee · Mirae Jang · Junsoo Park · Rackhyun Park ·

Chemistry Medicine
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PLoS ONE - DOI: 10.1371/journal.pone.0211041
Role of tumor-associated neutrophils in regulation of tumor growth in lung cancer development: A mathematical model

Yangjin Kim · Donggu Lee · Junho Lee · Seongwon Lee · Sean Lawler ·

Biology Medicine
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In this proposed approach, supervised learning techniques are used to extract cancer defining features and classify cancerous images from the normal mammogram images.

Recognition and Prediction of Breast Cancer using Supervised Diagnosis [10.1109/RTEICT46194.2019.9016921]


Patients with early stage breast or lung cancer aged 18 to 85 were enrolled (N = 302) at 2 cancer centers between April 2013 and March 2015 for the intervention component.

A Multi-faceted Intervention Aimed at Black-White Disparities in the Treatment of Early Stage Cancers: The ACCURE Pragmatic Quality Improvement trial. [10.1016/j.jnma.2019.03.001]


Patients with advanced genitourinary cancers face many challenges throughout their disease trajectory, and many will experience clinically relevant psychosocial distress.

Distress and Quality of Life Among Patients with Advanced Genitourinary Cancers. [10.1016/j.euf.2019.10.014]


The exploration of cancer prognostic factor has received increasing attention in recent years.

Albumin to fibrinogen ratio and fibrinogen to pre-albumin ratio are economical, simple and promising prognostic factors for solid malignancy. [10.21037/JTD.2019.08.96]


Although incidence rates have been stabilized, an estimated 154,050 Americans are expected to die from lung & bronchus cancer in 2018, accounting for approximately 25.

Abstract 2048: Stat3 downstream transthyretin stimulates tumor growth through regulation of tumor, immune and endothelial cells [10.1158/1538-7445.AM2019-2048]


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