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Journal of Neural Transmission
Research Hotspot & Journal Scope - transporter


Journal of Neural Transmission - DOI: 10.1007/s00702-019-01998-x
Association study and a systematic meta-analysis of the VNTR polymorphism in the 3′-UTR of dopamine transporter gene and attention-deficit hyperactivity disorder

Edna Grünblatt · Anna Maria Werling · Alexander Roth · Marcel Romanos · Susanne Walitza ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02016-w
Prediction of future weight change with dopamine transporter in patients with Parkinson’s disease

Kyoungjune Pak · Heeyoung Kim · Ju Won Seok · Myung Jun Lee · Seunghyeon Shin · Keunyoung Kim · Jae Meen Lee · Youngduk Seo · Bum Soo Kim · Sungmin Jun · In Joo Kim ·

Medicine
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Solute Carriers (SLCs) represent the largest family of transmembrane transporters in humans and constitute major determinants of cellular metabolism.

A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs [10.1101/726539]


The miR‐8‐3p mimic upregulated expression of glucose transporter 3, lactate dehydrogenase A and monocarboxylate transporter 1, and increased lactic acid dehydrogenase activity, lactate secretion, and ATP depletion in SCs; the miR‐8‐3p inhibitor had the opposite effects on these parameters.

MiR‐8‐3p regulates hyperthermia‐induced lactate secretion by targeting PPP2R5B in boar Sertoli cells [10.1002/mrd.23265]


This review will shed light on current status of excipients, which can be used to modulate membrane transporter inhibition potential and discuss the mechanism involved in it.

Shedding light on interaction of so called inactive ingredients (excipients) with permeability-glycoprotein [10.1016/J.JDDST.2019.05.022]


Finally, levetiracetam has no effect on the expression, or function of the products of the ABC transporter genes, ABCB1 (coding for P-gp), ABCC1, ABCC2, and ABCG2, in human cell lines.

Drug–drug interaction between levetiracetam and non-vitamin K antagonist anticoagulants [10.1093/eurheartj/ehy780]


ATP-binding cassette (ABC) transporter proteins have important functions in bacteria to maintain survival and homeostasis.

Immunization with the basic membrane protein (BMP) family ABC transporter elicits protection against Enterococcus faecium in a murine infection model. [10.1016/j.micinf.2019.09.002]


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