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Journal of Neural Transmission
Research Hotspot & Journal Scope - schizophrenia


Journal of Neural Transmission - DOI: 10.1007/s00702-019-02080-2
Pre-frontal parvalbumin interneurons in schizophrenia: a meta-analysis of post-mortem studies

Stephen J. Kaar · Ilinca Angelescu · Tiago Reis Marques · Oliver D. Howes ·

Biology Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-01993-2
Actigraphy studies and clinical and biobehavioural correlates in schizophrenia: a systematic review

Zi Ying Wee · Samantha Wei Lee Yong · Qian Hui Chew · Cuntai Guan · Tih Shih Lee · Kang Sim ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02120-x
The bimodal mechanism of interaction between dopamine and mitochondria as reflected in Parkinson’s disease and in schizophrenia

Dorit Ben-Shachar ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02108-7
Profiling of schizophrenia-associated serum peptides by MALDI-TOF-MS

Yingli Fu · Na Zhou · Yaqin Yu · Huiping Zhang · Yaoyao Sun · Mingyuan Zhang · Xin Chen · Yueying Wang · Qiong Yu ·

Medicine
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Aim To test the plausibility of the hypothesis that schizophrenia susceptibility might be associated with genetic variants predicted to cause impaired functioning of NMDAR, either directly or indirectly through impairment of the kinases that phosphorylate it.

In-silico investigation of coding variants potentially affecting the functioning of the glutamatergic N-methyl-D-aspartate receptor in schizophrenia [10.1097/YPG.0000000000000216]


The study compared the score of Schizophrenia Cognition Rating Scale of Indonesian version (SCoRSVI) and the score of the World Health Organization Disability Assessment Schedule (WHODAS 2.

The Effectiveness of the Combination Therapy of Risperidone, Group Psychotherapy and Occupational Therapy on Cognitive Functions and the Quality of Life of Schizophrenia Patients [10.5958/0976-5506.2019.02887.0]


Current guidelines for the treatment of schizophrenia focus on maximizing a patient’s adaptive functioning and quality of life in a recovery-oriented approach that encourages active collaboration among patients, caregivers, and mental health professionals to design and manage a customized and comprehensive care plan.

The modern perspective for long-acting injectables antipsychotics in the patient-centered care of schizophrenia [10.2147/NDT.S199048]


Non-competitive N-methyl-d-aspartate receptor antagonists mimic schizophrenia symptoms and produce immediate and persistent antidepressant effects.

Modulation of thalamo-cortical activity by the NMDA receptor antagonists ketamine and phencyclidine in the awake freely-moving rat [10.1016/j.neuropharm.2019.107745]


Aims: This randomized, double-blind, placebo-controlled, parallel-group, Phase 1b study examined the pharmacokinetics and pharmacodynamics of three doses of PF-06412562 (3 mg, 9 mg, and 45 mg twice daily) over 15 days in patients with schizophrenia receiving antipsychotics.

A novel approach to evaluate the pharmacodynamics of a selective dopamine D1/D5 receptor partial agonist (PF-06412562) in patients with stable schizophrenia [10.1177/0269881119855302]


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