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Journal of Neural Transmission
Research Hotspot & Journal Scope - neuronal


Journal of Neural Transmission - DOI: 10.1007/s00702-019-02005-z
Microglia activation induces oxidative injury and decreases SIRT3 expression in dopaminergic neuronal cells

De-Qi Jiang · Yan-Jiao Ma · Yong Wang · Hai-Xiao Lu · Shu-Hui Mao · Shi-Hua Zhao ·

Chemistry Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02045-5
Extremely low frequency magnetic field induces human neuronal differentiation through NMDA receptor activation

Alp Özgün · Ana Marote · Leo A Behie · António Salgado · Bora Garipcan ·

Chemistry Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02118-5
Lack of insulin resistance in response to streptozotocin treatment in neuronal SH-SY5Y cell line

Fruzsina Bagaméry · Kamilla Varga · Kitti Kecsmár · István Vincze · Éva Szökő · Tamás Tábi ·

Chemistry Medicine
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The activity-regulated cytoskeleton-associated protein, Arc, is highly expressed in neuronal dendrites and is involved in synaptic scaling and plasticity.

The Capsid Domain of Arc Changes Its Oligomerization Propensity through Direct Interaction with the NMDA Receptor. [10.1016/j.str.2019.04.001]


Methylation profiling classified it as a diffuse leptomeningeal glioneuronal tumor (DLGNT) with low confidence.

High-grade glioneuronal tumor with an ARHGEF2–NTRK1 fusion gene [10.1007/s10014-019-00345-y]


Impairments of neural circuit switching and imbalance between inhibitory and excitatory neuronal populations are likely responsible for episodic sleep disturbances, in particular RBD.

Sleep Disturbance as Potential Risk and Progression Factor for Parkinson’s Disease [10.3233/JPD-191627]


Fundamentally, microglia have two activation states, a pro-inflammatory neurotoxic (M1) and an anti-inflammatory neuroprotective (M2) phenotype, and their conversion from M1-like to M2-like microglia may provide therapeutic benefits to prevent neuronal loss in neurodegenerative diseases such as Parkinson's disease (PD).

Mechanism underlying β2-AR agonist-mediated phenotypic conversion of LPS-activated microglial cells [10.1016/j.jneuroim.2019.03.017]


These findings were recapitulated in rodent and human neuronal models of αS dyshomeostasis (overexpression; patient-derived triplication or E46K mutation; E46K mice).

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. [10.1016/j.molcel.2018.11.028]


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