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Journal of Neural Transmission
Research Hotspot & Journal Scope - human


Journal of Neural Transmission - DOI: 10.1007/s00702-019-02045-5
Extremely low frequency magnetic field induces human neuronal differentiation through NMDA receptor activation

Alp Özgün · Ana Marote · Leo A Behie · António Salgado · Bora Garipcan ·

Chemistry Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02029-5
Botulinum toxin type D blocks autonomic cholinergic synapses in humans: discussion of a potential therapeutic use

Dirk Dressler · Katja Kollewe · Tilmann H. C. Kruger · Niklas Gade · Stefan Sikorra · Hans Bigalke ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-01984-3
The first identification of nesfatin-1-expressing neurons in the human bed nucleus of the stria terminalis

Artur Pałasz · Katarzyna Bogus · Aleksandra Suszka-Świtek · Andrzej Kaśkosz · Shirley Saint-Remy · Aneta Piwowarczyk-Nowak · Łukasz Filipczyk · John J Worthington · Kinga Mordecka-Chamera · Karol Kostro · Grzegorz Bajor · Ryszard Wiaderkiewicz ·

Biology Medicine
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Lung adenocarcinoma (LAD) is a human malignancy successfully treated with the tyrosine kinase inhibitor (TKI) gefitinib; however, the enrichment of therapy resistant cancer stem cells (CSCs) in such patients is assumed to be a source of treatment failure.

Targeting histone deacetylase SIRT1 selectively eradicates EGFR TKI-resistant cancer stem cells via regulation of mitochondrial oxidative phosphorylation in lung adenocarcinoma [10.1016/j.neo.2019.10.006]


Synaesthesia is a neurological phenomenon that can offer an unusually clear window into the factors influencing human sensory perception and the range of normal experience [1,2].

Bridging senses: novel insights from synaesthesia [10.1098/rstb.2019.0022]


Characterization of the mutants revealed that they have a decreased susceptibility to human beta defensin-3 and LL37, which are innate immune factors.

An alternative nisin A resistance mechanism affects virulence in Staphylococcus aureus [10.1101/716191]


Overall, our results support the hypothesis that eSTRs contribute to a range of human phenotypes, and our data should serve as a valuable resource for future studies of complex traits.

The impact of short tandem repeat variation on gene expression [10.1038/s41588-019-0521-9]


Human A3 adenosine receptor hA3AR has been implicated in gastrointestinal cancer, where its cellular expression has been found increased, thus suggesting its potential as a molecular target for novel anticancer compounds.

Design, Synthesis and Evaluation of New Indolylpyrimidylpiperazines for Gastrointestinal Cancer Therapy [10.3390/molecules24203661]


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