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Journal of Neural Transmission
Research Hotspot & Journal Scope - hippocampal


Journal of Neural Transmission - DOI: 10.1007/s00702-019-01992-3
Abnormal hippocampal subfields are associated with cognitive impairment in Essential Tremor

Shweta Prasad · Apurva Shah · Ketaki Swapnil Bhalsing · Keshav J Kumar · Jitender Saini · Madhura Ingalhalikar · Pramod Kumar Pal ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02068-y
Cognitive effects of dance-movement intervention in a mixed group of seniors are not dependent on hippocampal atrophy

Sylvie Kropacova · Kristina Mitterova · Patricia Klobusiakova · Lubos Brabenec · Lubomira Anderkova · Nela Nemcova-Elfmarkova · Zuzana Balazova · Ivan Rektor · Roman Grmela · Lenka Svobodová · Pavlina Vaculikova · Irena Rektorova ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02073-1
FGF2 and dual agonist of NCAM and FGF receptor 1, Enreptin, rescue neurite outgrowth loss in hippocampal neurons expressing mutated huntingtin proteins

Mirolyuba Ilieva · Troels T. Nielsen · Tanja Michel · Stanislava Pankratova ·

Chemistry Medicine
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Consistent with the key role played by the downscaling of synaptic transmission in memory consolidation, we found that NMDAR‐dependent long‐term depression was abnormal in ex vivo hippocampal slices acutely prepared from IP3R2‐deficient mice, a deficit that could be prevented upon supplementation with D‐serine ‐ an NMDA‐receptor co‐agonist whose synthesis depends upon astrocytes' activity.

Impairments in remote memory caused by the lack of Type 2 IP3 receptors [10.1002/glia.23679]


Our results demonstrate that AVL-3288 improves hippocampal synaptic plasticity, and learning and memory performance after TBI in the chronic recovery period.

Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury [10.1371/journal.pone.0223180]


In addition to hippocampal neurodegeneration, Brain-derived neurotrophic factor (BDNF), cAMP response element binding (CREB), Glycogen synthase kinase 3 (GSK3), and Protein kinase B (Akt-1) were assessed in isolated hippocampus.

Pharmacological evidence for lithium-induced neuroprotection against methamphetamine-induced neurodegeneration via Akt-1/GSK3 and CREB-BDNF signaling pathways [10.22038/ijbms.2019.30855.7442]


Declining episodic memory is common among otherwise healthy older adults, in part due to negative effects of aging on hippocampal circuits.

Cardiorespiratory fitness predicts greater hippocampal volume and rate of episodic associative learning in older adults [10.1101/578237]


Most report impairments in tasks assessing spatial memory with corresponding increases in hippocampal oxidative stress and inflammatory responses originating in the gut.

Reviewing the effects of dietary salt on cognition: mechanisms and future directions. [10.6133/apjcn.201903_28(1).0002]


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