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Journal of Neural Transmission
Research Hotspot & Journal Scope - brain


Journal of Neural Transmission - DOI: 10.1007/s00702-019-02076-y
Subthalamic nucleus deep brain stimulation improves dyskinesias in Parkinson’s disease beyond levodopa reduction

James M. Mossner · Parag G. Patil · Kelvin L. Chou ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02034-8
Dynamics of device-based treatments for Parkinson’s disease in Germany from 2010 to 2017: application of continuous subcutaneous apomorphine, levodopa–carbidopa intestinal gel, and deep brain stimulation

Daniel Richter · Dirk Bartig · Wolfgang Jost · Christoph Jörges · Britta Stumpe · Ralf Gold · Christos Krogias · Lars Tönges ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-01972-7
Longterm outcome of cognition, affective state, and quality of life following subthalamic deep brain stimulation in Parkinson’s disease

Doreen Gruber · Lisa Calmbach · Andrea A. Kühn · Patricia Krause · Ute A. Kopp · Gerd-Helge Schneider · Andreas Kupsch ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02038-4
SNCA rs11931074 polymorphism correlates with spontaneous brain activity and motor symptoms in Chinese patients with Parkinson’s disease

Qian-Qian Si · Yong-Sheng Yuan · Yan Zhi · Min Wang · Jian-Wei Wang · Yu-Ting Shen · Li-Na Wang · Jun-Yi Li · Xi-Xi Wang · Ke-Zhong Zhang ·

Medicine
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Then we ran Exome-Wide Association Scans (EWAS) within sequenced PD cases (N = 113), testing both motor and non-motor PD endophenotypes, as well as their associations with Polygenic Risk Scores (PRS) influencing brain subcortical volumes.

Whole Exome Sequencing Study of Parkinson Disease and Related Endophenotypes in the Italian Population [10.3389/fneur.2019.01362]


Using both simulation and in-vivo experimental datasets, we show that both methods can successfully identify task related brain activation.

Analysis of continuous infusion functional PET (fPET) in the human brain [10.1101/778357]


We developed a highly efficient and selective NG2 glia depletion method using small-molecule inhibitors of platelet-derived growth factor signaling in cultured brain slices.

NG2 glia are required for maintaining microglia homeostatic state [10.1101/667402]


Such claim has been justified by the conviction, sustained since the 1990s by the capabilities attributed to neuroimaging technologies, that somehow ‘the mind is the brain’, that the brain sciences can illuminate the full range of human experience and behavior, and that neuroscientific knowledge will have dramatic implications for views of the human, and challenge supposedly established beliefs and practices in domains ranging from self and personhood to the political organization of society.

What makes neuroethics possible? [10.1177/0952695118800410]


Finally, we argue that addicted brains must be understood as one component of broader networks of symptoms and environmental and social factors that are impossible to model in laboratory animals.

Are animal models of addiction useful? [10.1111/add.14764]


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