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Journal of Neural Transmission
Research Hotspot & Journal Scope - Parkinson


Journal of Neural Transmission - DOI: 10.1007/s00702-019-02025-9
α-Synuclein in Parkinson’s disease: causal or bystander?

Peter Riederer · Daniela Berg · Nicolas Casadei · Fubo Cheng · Joseph Classen · Christian Dresel · Wolfgang Jost · Rejko Krüger · Thomas Müller · Heinz Reichmann · Olaf Rieß · Alexander Storch · Sabrina Strobel · Thilo van Eimeren · Hans-Ullrich Völker · Jürgen Winkler · Konstanze F. Winklhofer · Ullrich Wüllner · Friederike Zunke · Camelia-Maria Monoranu ·

Biology Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-018-1898-9
Is Braak staging valid for all types of Parkinson’s disease?

Kurt A Jellinger ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-01996-z
Olfaction and taste in Parkinson’s disease: the association with mild cognitive impairment and the single cognitive domain dysfunction

Maria Paola Cecchini · Angela Federico · Alice Zanini · Elisa Mantovani · Carla Masala · Michele Tinazzi · Stefano Tamburin ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-01997-y
Dopaminergic modulation of striatal function and Parkinson’s disease

Shenyu Zhai · Weixing Shen · Steven M Graves · D James Surmeier ·

Biology Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-01979-0
Association between physical activity and dementia’s risk factors in patients with Parkinson’s disease

Mohammad Alwardat · Tommaso Schirinzi · Giulia Di Lazzaro · Giulia Maria Sancesario · Donatella Franco · Paola Imbriani · Paola Sinibaldi Salimei · Sergio Bernardini · Nicola Biagio Mercuri · Antonio Pisani ·

Psychology Medicine
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Many, but not all, of these neuronal abnormalities were abrogated by small interfering RNA (siRNA) knockdown of α‐synuclein, implicating α‐synuclein as a potent, albeit partial, mediator of HO‐1's neurodystrophic effects in these parkinsonian mice.

Glial HMOX1 expression promotes central and peripheral α‐synuclein dysregulation and pathogenicity in parkinsonian mice [10.1002/glia.23645]


On the other hand, we confirmed MR Parkinsonism Index (MRPI) and pons area to midbrain area ratio (P/M) have adequate diagnostic value to support PSP-RS clinical diagnosis compared with both PD and HC, but low sensitivity and specificity profile in differentiating PSP-P from PD as well as from HC.

Midbrain MRI assessments in progressive supranuclear palsy subtypes [10.1136/jnnp-2019-321354]


Such pattern was discovered using a de novo early Parkinson’s disease cohort (n = 21), and a cohort of Controls (n = 30).

Longitudinal Connectomes as a Candidate Progression Marker for Prodromal Parkinson’s Disease [10.3389/fnins.2018.00967]


Therefore, leaving the bed independently is troublesome for Parkinson patients.

Wearable Device for Sitting Up Support of Parkinson Patients [10.31031/RMES.2019.07.000673]


FindingsProgressive supranuclear palsy shows Parkinsonian gait—slower walking speed and shorter step length.

The combination of short-step and wide-based gait is a gait characteristic in progressive supranuclear palsy: a retrospective, cross-sectional study [10.1007/s41999-019-00211-2]


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