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Journal of Neural Transmission
Research Hotspot & Journal Scope - Dopaminergic


Journal of Neural Transmission - DOI: 10.1007/s00702-019-01997-y
Dopaminergic modulation of striatal function and Parkinson’s disease

Shenyu Zhai · Weixing Shen · Steven M Graves · D James Surmeier ·

Biology Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-01970-9
Mesencephalic and extramesencephalic dopaminergic systems in Parkinson’s disease

Fanni F Geibl · Martin T Henrich · Wolfgang H Oertel ·

Psychology Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-02005-z
Microglia activation induces oxidative injury and decreases SIRT3 expression in dopaminergic neuronal cells

De-Qi Jiang · Yan-Jiao Ma · Yong Wang · Hai-Xiao Lu · Shu-Hui Mao · Shi-Hua Zhao ·

Chemistry Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-01974-5
Dopaminergic denervation using [123I]-FPCIT and pain in Parkinson’s disease: a correlation study

Estelle Dellapina · Jean Pellaprat · Djilali Adel · Jerome Llido · Estelle Harroch · Jean Baptiste Martini · Aurélie Kas · Anne Sophie Salabert · Fabienne Ory-Magne · Pierre Payoux · Christine Brefel-Courbon ·

Medicine
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Importantly, this hyperdopaminergic phenotype was selective for risky decision-making, as delay discounting performance was not predictive of phasic dopamine release or dopamine supply.

Risky decision-making predicts dopamine release dynamics in nucleus accumbens shell [10.1038/s41386-019-0527-0]


These results show that sub-chronic ketamine treatment in mice mimics the dopaminergic alterations in patients with psychosis, and suggest an underlying neurocircuit involving PV interneuron hypofunction in frontal cortex and hippocampus as well as activation of midbrain dopamine neurons.

Mesocorticolimbic circuit mechanisms underlying the effects of ketamine on dopamine: a translational imaging study [10.1101/748665]


We therefore investigated the in vivo relationship between striatal dopamine synthesis capacity and prefrontal grey matter volume in treatment-responsive patients with psychosis, and compared them to treatment non-responsive patients, where dopaminergic mechanisms are not thought to be central.

The relationship between grey matter volume and striatal dopamine function in psychosis: a multimodal 18F-DOPA PET and voxel-based morphometry study [10.1038/s41380-019-0570-6]


Methods: The Dopaminergic nerve precursor cell line(MN9D) cells that served as a PD model in this study underwent damage induced by 100 μM 1-methyl-4-phenyl pyridine (MPP+).

The Effect of Fucoidan on Cellular Oxidative Stress and the CatD-Bax Signaling Axis in MN9D Cells Damaged by 1-Methyl-4-Phenypyridinium [10.3389/fnagi.2018.00429]


In conclusion, our results revealed that NBP exerted dopaminergic neuroprotection through inhibition of microglia-mediated neuroinflammation, suggesting the promising therapeutic effect of NBP for PD.

Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation [10.3389/fnagi.2019.00044]


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