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Journal of Neural Transmission
Research Hotspot & Journal Scope - Alzheimer


Journal of Neural Transmission - DOI: 10.1007/s00702-019-02022-y
High-frequency repetitive transcranial magnetic stimulation combined with cognitive training improves cognitive function and cortical metabolic ratios in Alzheimer’s disease

Fengxia Zhang · Yuanyuan Qin · Lingfeng Xie · Caixia Zheng · Xiaolin Huang · Min Zhang ·

Medicine
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Journal of Neural Transmission - DOI: 10.1007/s00702-019-01982-5
Validation of a prototype tau Thr231 phosphorylation CSF ELISA as a potential biomarker for Alzheimer’s disease

Joana R F Santos · Chris Bauer · Johannes Schuchhardt · Dirk Wedekind · Katharina Waniek · Ingolf Lachmann · Jens Wiltfang · Jonathan Vogelgsang ·

Medicine
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Methods and Results Four hundred seventy‐seven patients with mild‐to‐moderate Alzheimer disease were randomized to the calcium‐channel blocker nilvadipine 8 mg/day or placebo for 78 weeks.

Blood Pressure Lowering With Nilvadipine in Patients With Mild‐to‐Moderate Alzheimer Disease Does Not Increase the Prevalence of Orthostatic Hypotension [10.1161/JAHA.119.011938]


Tau PET uptake was tied to the onset of cognitive dysfunction, and there was a higher amount, and different regional pattern of binding compared to late onset, non-familial Alzheimer's disease.

Tau PET in autosomal dominant Alzheimer’s disease: relationship with cognition, dementia and other biomarkers [10.1093/brain/awz019]


Both hyposmia and weight loss are seen in the years preceding diagnosis with Alzheimer dementia.

Mortality Risk in Older Adults: What the Nose Knows [10.7326/M19-1013]


To better understand the pathobiology of Alzheimer's disease we measured levels of tau PET binding in individuals with dominantly inherited Alzheimer's disease using data from the Dominantly Inherited Alzheimer Network (DIAN).

Tau PET in autosomal dominant Alzheimer’s disease: relationship with cognition, dementia and other biomarkers [10.1093/brain/awz019]


Sporadic Alzheimer’s disease (sAD) is the most prevalent neurodegenerative pathology with no effective therapy until date.

Mesenchymal Stem Cells Therapy Improved the Streptozotocin-Induced Behavioral and Hippocampal Impairment in Rats [10.1007/s12035-019-01729-z]



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