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Journal of Neural Transmission
Research Hotspot & Journal Scope - Alzheimer

Journal of Neural Transmission - DOI: 10.1007/s00702-019-02022-y
High-frequency repetitive transcranial magnetic stimulation combined with cognitive training improves cognitive function and cortical metabolic ratios in Alzheimer’s disease

Fengxia Zhang · Yuanyuan Qin · Lingfeng Xie · Caixia Zheng · Xiaolin Huang · Min Zhang ·

Journal of Neural Transmission - DOI: 10.1007/s00702-019-01982-5
Validation of a prototype tau Thr231 phosphorylation CSF ELISA as a potential biomarker for Alzheimer’s disease

Joana R F Santos · Chris Bauer · Johannes Schuchhardt · Dirk Wedekind · Katharina Waniek · Ingolf Lachmann · Jens Wiltfang · Jonathan Vogelgsang ·


In particular, low-molecular-weight aggregates of the Alzheimer amyloid-β peptide (Aβ) have attracted increasing interest because of their role in cytotoxicity and neuronal apoptosis, typical of aggregation-related diseases.

How Fluorescent Tags Modify Oligomer Size Distributions of the Alzheimer Peptide [10.1016/j.bpj.2018.12.010]

Blood samples from Alzheimer’s patients also showed an increase in PROS1 levels, with a close correlation with amyloid-beta build-up in the brain.

Deep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer’s disease [10.1038/s12276-019-0326-z]

Furthermore, the prediction of the pKa value for the peptide is done with great accuracy as well as the ability of the studied molecule in acting as an efficient inhibitor of the formation of Advanced Glycation Endproducts (AGEs), which comprises of a useful knowledge for the development of drugs for preventing Alzheimer, Diabetes and Parkinson diseases.

Conceptual Density Functional Theory Study of the Chemical Reactivity Properties and Bioactivity Scores of the Leu-Enkephalin Opioid Peptide Neurotransmitter [10.4236/CMB.2019.91002]

To better understand the pathobiology of Alzheimer's disease we measured levels of tau PET binding in individuals with dominantly inherited Alzheimer's disease using data from the Dominantly Inherited Alzheimer Network (DIAN).

Tau PET in autosomal dominant Alzheimer’s disease: relationship with cognition, dementia and other biomarkers [10.1093/brain/awz019]

Recovery of quenched fluorescence upon addition of anti-Alzheimer drugs in a concentration-based manner.

Interaction of synthesized nitrogen enriched graphene quantum dots with novel anti-Alzheimer’s drugs: spectroscopic insights [10.1080/07391102.2019.1619625]

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