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Journal of Integrative Medicine
Research Hotspot & Journal Scope - vivo


Journal of Integrative Medicine - DOI: 10.1016/j.joim.2019.02.001
Medicinal properties of Angelica archangelica root extract: Cytotoxicity in breast cancer cells and its protective effects against in vivo tumor development.

Carlos R Oliveira · Daniel G Spindola · Daniel M Garcia · Adolfo Erustes · Alexandre Bechara · Caroline Palmeira-Dos-Santos · Soraya S Smaili · Gustavo J S Pereira · André Hinsberger · Ezequiel P Viriato · Maria Cristina Marcucci · Alexandra C H F Sawaya · Samantha L Tomaz · Elaine G Rodrigues · Claudia Bincoletto ·

Chemistry Medicine
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Journal of Integrative Medicine - DOI: 10.1016/j.joim.2019.02.004
Evaluation of in vitro cell and blood compatibility and in vivo analgesic activity of plant-derived dietary supplements.

Stefania Lamponi · Anna Maria Aloisi · Claudia Bonechi · Marco Consumi · Alessandro Donati · Gemma Leone · Claudio Rossi · Gabriella Tamasi · Luana Ghiandai · Ersilia Ferrini · Paolo Fiorenzani · Ilaria Ceccarelli · Agnese Magnani ·

Chemistry Medicine
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Journal of Integrative Medicine - DOI: 10.1016/j.joim.2018.11.008
Telfairia occidentalis (Cucurbitaceae) pulp extract mitigates rifampicin-isoniazid-induced hepatotoxicity in an in vivo rat model of oxidative stress.

Lucky Legbosi Nwidu · Yibala Ibor Oboma ·

Medicine
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On average, >60% of peripheral blood cells expressed the transgene after in vivo selection with low-dose O6BG/bis-chloroethylnitrosourea (BCNU).

Targeted Integration and High-Level Transgene Expression in AAVS1 Transgenic Mice after In Vivo HSC Transduction with HDAd5/35++ Vectors. [10.1016/j.ymthe.2019.08.006]


Here, combining mouse auditory psychophysical behavior and in vivo two-photon imaging from the auditory cortex, we investigate how sensory-to-category transformation is implemented by cortical neurons during a stimulus categorization task.

Sensory-to-Category Transformation via Dynamic Reorganization of Ensemble Structures in Mouse Auditory Cortex [10.1016/j.neuron.2019.06.004]


This unit describes several protocols for ex vivo generation of murine and human osteoclasts, allowing study of the effects of specific cells, cytokines, or chemical substances on osteoclast formation and activity without the need for expensive and time‐consuming animal experiments.

Generation and Analysis of Human and Murine Osteoclasts [10.1002/cpim.74]


Conclusions: The fully automated exposure platform described herein provides reproducible aerosol generation, conforms to recommended guidelines on chemical testing, and therefore is suitable for future in vivo toxicological assessments to examine potential respiratory hazards of aerosolized nano-enabled consumer products.

Characterization of an aerosol generation system to assess inhalation risks of aerosolized nano-enabled consumer products [10.1080/08958378.2019.1685613]


For this purpose, ex-vivo murine experiments were performed to quantify the biokinetics and biodistribution of the major organs, plasma, tumor, and skin.

Pharmacokinetic biodistribution assessment of Phosphorescent sensor, PtG4 Oxyphor in mice for optimization of in vivo oxygenation imaging [10.1117/12.2513220]


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