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Journal of Diabetes Research
Research Hotspot & Journal Scope - Signaling


Journal of Diabetes Research - DOI: 10.1155/2019/4021623
Visfatin Induces Inflammation and Insulin Resistance via the NF-κB and STAT3 Signaling Pathways in Hepatocytes

Yu Jung Heo · Sung-E Choi · Ja Young Jeon · Seung Jin Han · Dae Jung Kim · Yup Kang · Kwan Woo Lee · Hae Jin Kim ·

Chemistry Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/2510105
Nrf2-Heme Oxygenase-1 Attenuates High-Glucose-Induced Epithelial-to-Mesenchymal Transition of Renal Tubule Cells by Inhibiting ROS-Mediated PI3K/Akt/GSK-3β Signaling

Jong Ho Shin · Kyeong Min Kim · Jin Uk Jeong · Jae Min Shin · Ju Hyung Kang · Kitae Bang · Joo-Heon Kim ·

Chemistry Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/5920676
Platelet-Rich Plasma with Endothelial Progenitor Cells Accelerates Diabetic Wound Healing in Rats by Upregulating the Notch1 Signaling Pathway

Cheng Zhang · Yu Zhu · Shengdi Lu · Wanrun Zhong · Yanmao Wang · Yimin Chai ·

Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/4650906
To Explore the Pathogenesis of Vascular Lesion of Type 2 Diabetes Mellitus Based on the PI3K/Akt Signaling Pathway

Jia-Rong Gao · Xiu-Juan Qin · Zhao-Hui Fang · Li-Shan · Li-Ping Han · Hui-Jiang · Ming-Fei Guo · Nan-Nan Jiang ·

Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/2376512
High Glucose with Insulin Induces Cell Cycle Progression and Activation of Oncogenic Signaling of Bladder Epithelial Cells Cotreated with Metformin and Pioglitazone

Daejin Kim · Byul-Nim Ahn · YeongSeok Kim · Dae Young Hur · Jae Wook Yang · Ga Bin Park · Jung Eun Jang · Eun Ju Lee · Min Jeong Kwon · Tae Nyun Kim · Mi Kyung Kim · Jeong Hyun Park · Byoung Doo Rhee · Soon Hee Lee ·

Chemistry Medicine
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These data suggest that NYX‐2925 facilitates homeostatic plasticity by initially increasing synaptic GluN2B via metabotropic‐like NMDAR signaling.

NYX‐2925 induces metabotropic N‐methyl‐d‐aspartate receptor (NMDAR) signaling that enhances synaptic NMDAR and α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor [10.1111/jnc.14845]


Here, we demonstrated that Gal-4 could bind to CD14 on monocytes and induce their differentiation into macrophage-like cells through the MAPK signaling pathway.

Galectin-4 Interaction with CD14 Triggers the Differentiation of Monocytes into Macrophage-like Cells via the MAPK Signaling Pathway [10.4110/in.2019.19.e17]


Because of continuous probing, this procedure increases signaling overhead and energy consumption of the MT.

Location-Based Discovery and Vertical Handover in Heterogeneous Low-Power Wide-Area Networks [10.1109/JIOT.2019.2935804]


Data presented here links the IGF1 and p53 signaling pathways with ZYG11A action.

Identification of ZYG11A as a candidate IGF1-dependent proto-oncogene in endometrial cancer [10.18632/oncotarget.27055]


These metabolic defects were associated with an up-regulation of genes within the pro-fibrotic TGF-β signaling pathway and increased levels of cellular hydroxyproline within the livers of the male offspring.

Preconception paternal alcohol exposure exerts sex-specific effects on offspring growth and long-term metabolic programming [10.1186/s13072-019-0254-0]


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