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Journal of Diabetes Research
Research Hotspot & Journal Scope - Metformin


Journal of Diabetes Research - DOI: 10.1155/2019/7676909
Monotherapy with Metformin versus Sulfonylureas and Risk of Cancer in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis

Abraham Nigussie Mekuria · Yohanes Ayele · Assefa Tola · Kirubel Minsamo Mishore ·

Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/9804708
Comparative Efficacy and Safety of Metformin, Glyburide, and Insulin in Treating Gestational Diabetes Mellitus: A Meta-Analysis

Lanlan Guo · Jing Ma · Jia Tang · Dingyao Hu · Wei Zhang · Xue Zhao ·

Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/2376512
High Glucose with Insulin Induces Cell Cycle Progression and Activation of Oncogenic Signaling of Bladder Epithelial Cells Cotreated with Metformin and Pioglitazone

Daejin Kim · Byul-Nim Ahn · YeongSeok Kim · Dae Young Hur · Jae Wook Yang · Ga Bin Park · Jung Eun Jang · Eun Ju Lee · Min Jeong Kwon · Tae Nyun Kim · Mi Kyung Kim · Jeong Hyun Park · Byoung Doo Rhee · Soon Hee Lee ·

Chemistry Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/9484717
Association between Metformin Use and Coronary Artery Calcification in Type 2 Diabetic Patients

Yi Lu · Yidong Wang · Ting Weng · Zexin Chen · Xiujuan Sun · Jia Wei · Zhejun Cai · Meixiang Xiang ·

Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/7602427
Metformin Reduces Lipotoxicity-Induced Meta-Inflammation in β-Cells through the Activation of GPR40-PLC-IP3 Pathway

Ximei Shen · Beibei Fan · Xin Hu · Liufen Luo · Yuanli Yan · Liyong Yang ·

Medicine
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5%), metformin plus DPP4 inhibitors in dual therapy (77.

Prescription patterns of antihyperglycemic drugs in elderly patients in Spain: A national cross-sectional study. [10.1016/j.rce.2019.05.011]


The goal is to achieve a long and steady release of metformin hydrochloride in future formulations with this drug.

PVP/Clay/Vanadium Oxide Nanocomposites Development and Characterization for Potential Use as Controlled Drug Release Matrix in Diabetes’ Treatment [10.4236/msa.2019.1012056]


Metformin combined with navitoclax or venetoclax efficiently inhibited tumor growth, conferred survival benefits and induced tumor infiltration by immune cells.

Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy [10.1038/s41467-019-08541-2]


Our data unravel a novel molecular mechanism by which metformin enhances glucose uptake and acts renoprotectively by reducing SHIP2 activity.

Metformin increases glucose uptake and acts renoprotectively by reducing SHIP2 activity [10.1096/fj.201800529RR]


RESULTS Metformin effectively prevented cyclosporine A-induced renal dysfunction with increased creatinine clearance rate, reduced blood urea nitrogen and serum creatinine, as well as less proteinuria in comparison to the cyclosporine A group.

Metformin attenuates cyclosporine A-induced renal fibrosis in rats. [10.1097/TP.0000000000002864]


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