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Journal of Diabetes Research
Research Hotspot & Journal Scope - Kidney


Journal of Diabetes Research - DOI: 10.1155/2019/9030893
Chinese Herbal Medicine in Ameliorating Diabetic Kidney Disease via Activating Autophagy

Yuyang Wang · Hailing Zhao · Qian Wang · Xuefeng Zhou · Xiaoguang Lu · Tongtong Liu · Yongli Zhan · Ping Li ·

Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/2697672
The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease

Zhenzhen Lu · Yifei Zhong · Wangyi Liu · Ling Xiang · Yueyi Deng ·

Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/4709715
Hyperinsulinemia Can Cause Kidney Disease in the IGT Stage of OLETF Rats via the INS/IRS-1/PI3-K/Akt Signaling Pathway

Yi Zhang · Shaohua Yang · Xiao Cui · Juhong Yang · Miaoyan Zheng · Junya Jia · Fei Han · Xiaoyun Yang · Jingyu Wang · Zhenhong Guo · Bai Chang · Baocheng Chang ·

Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/5359635
Inflammation and Kidney Injury in Diabetic African American Men

Lei Cao · Ava Boston · Olugbemiga Jegede · Heather A Newman · Scott H Harrison · Robert H Newman · Elimelda Moige Ongeri ·

Medicine
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Journal of Diabetes Research - DOI: 10.1155/2019/8153140
Characterization of Novel Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys

Ayaka Domon · Kentaro Katayama · Yuki Tochigi · Hiroetsu Suzuki ·

Medicine
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Preimplantation kidney biopsies from ECD (n = 41) and standard-criteria donor (n = 39) were evaluated for real-time quantitative polymerase chain reaction gene expression using the TaqMan Gene Expression Array Plates system for genes Toll-like receptor-4 (TLR4), high-mobility group box 1, nuclear factor kappa beta, myeloid differentiation primary response 88, interferon (IFN)-γ, interleukin (IL)1-β, tumor necrosis factor alpha, caspase-1 (CASP1), intercellular adhesion molecule 1, IL-10, heme oxygenase 1 hypoxia-inducible factor 1 (HIF-1), monocyte chemotactic protein 1, transforming growth factor beta 1, TIR-domain containing adapter inducing interferon-β (TRIF), TRIF-related adaptor molecule, interferon regulatory factor 3 (IRF-3), receptor-interacting protein 1, IFNβ-1, and nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin protein 3 complex.

Activation of HMGB1–TLR4 Pathway and Inflammasome Contribute to Enhanced Inflammatory Response in Extended Criteria and Kidneys With KDPI ≥85% [10.1097/TP.0000000000003048]


EdAP exhibited potent inhibition against influenza virus multiplication in Madin–Darby canine kidney (MDCK) cells transfected with human α2-6-sialyltransferase (SIAT1) cDNA and did not show any toxicity toward the cells.

Design, Synthesis, and Biological Evaluation of EdAP, a 4′-Ethynyl-2′-Deoxyadenosine 5′-Monophosphate Analog, as a Potent Influenza a Inhibitor [10.3390/molecules24142603]


TRP channel subfamily C, member 5 (TRPC5) helps regulate a tight balance of cytoskeletal dynamics in podocytes and is suggested to be involved in the pathogenesis of proteinuric kidney diseases, such as focal segmental glomerulosclerosis (FSGS).

Discovery of a Potent and Selective TRPC5 Inhibitor, Efficacious in a Focal Segmental Glomerulosclerosis Model. [10.1021/acsmedchemlett.9b00430]


AmB-M could achieve a sustained and slow release of AmB, low hemolysis activity and negligible kidney toxicity when compared with commercial AmB injection.

Linolenic acid-modified MPEG-PEI micelles for encapsulation of amphotericin B. [10.4155/fmc-2018-0580]


OBJECTIVES Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney disease characterized by multiple and bilateral cystic dilation of renal tubules.

α-lipoic acid in patients with autosomal dominant polycystic kidney disease. [10.1016/j.nut.2019.110594]


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