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Journal of Clinical Oncology
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.9000

RELAY: A multinational, double-blind, randomized Phase 3 study of erlotinib (ERL) in combination with ramucirumab (RAM) or placebo (PL) in previously untreated patients with epidermal growth factor receptor mutation-positive (EGFRm) metastatic non-small cell lung cancer (NSCLC).

Kazuhiko Nakagawa · Edward B. Garon · Takashi Seto · Makoto Nishio · Santiago Ponce Aix · Chao-Hua Chiu · Keunchil Park · Silvia Novello · Ernest Nadal · Fumio Imamura · Kiyotaka Yoh · Jin-Yuan Shih · Kwok Hung Au · Denis Moro-Sibilot · Sotaro Enatsu · Annamaria Zimmermann · Bente Frimodt-Moller · Carla M. Visseren Grul · Martin Reck ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.7_SUPPL.551

Alterations in DNA damage repair (DDR) genes and outcomes to systemic therapy in 225 immune-oncology (IO) versus tyrosine kinase inhibitor (TKI) treated metastatic clear cell renal cell carcinoma (mccRCC) patients (pts).

Yasser Ged · Joshua Chaim · Andrea Knezevic · Maria I. Carlo · Ashley Foster · Darren R. Feldman · Min Yuen Teo · Nadeem Riaz · Chung-Han Lee · Sujata Patil · Timothy A. Chan · A. Ari Hakimi · Robert J. Motzer · Martin H. Voss ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.2587

Real-world outcomes of underrepresented patient populations treated with immune checkpoint inhibitors (ICIs): African American descent, poor ECOG performance status, and chronic viral infections.

Neil J. Shah · Matthew Blackburn · Michael R. Cook · Anas Belouali · Michael Serzan · William J Kelly · Athanasios Bikas · Chul Kim · Subha Madhavan · Stephen V. Liu · Michael B. Atkins ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.7012

Primary results of the phase 4 BYOND study of bosutinib (BOS) for pretreated chronic phase (CP) chronic myeloid leukemia (CML).

Carlo Gambacorti-Passerini · Camille N. Abboud · Bjørn Tore Gjertsen · Tim H. Brümmendorf · B. Douglas Smith · Pilar Giraldo-Castellano · Ulla Olsson-Strömberg · Susanne Saussele · Nathalie Bardy-Bouxin · Andrea Viqueira · Eric Leip · Jocelyn M Leone · Gianantonio Rosti · Justin M. Watts · Frank Giles · Andreas Hochhaus · Byond Study Investigators ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.1018

In-depth gene expression analysis of premenopausal patients with HR+/HER2− advanced breast cancer (ABC) treated with ribociclib-containing therapy in the Phase III MONALEESA-7 trial.

Yen-Shen Lu · Sara A. Hurvitz · Fei Su · Wei He · Debu Tripathy · Saul Campos Gomez · Kyung Hae Jung · Marco Colleoni · Paul Wheatley-Price · Sherko Kuemmel · Nadia Harbeck · F. Franke · Seock-Ah Im · Louis W.C. Chow · Tetiana Taran · Karen Rodriguez-Lorenc · Naveen Babbar · Aditya Bardia ·

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Despite a plethora of studies demonstrating significant morbidity and mortality due to community-acquired respiratory viral (CRV) infections in intensively treated hematology patients, and despite the availability of evidence-based guidelines for the diagnosis and management of respiratory viral infections in this setting, there is no uniform inclusion of respiratory viral infection management in the clinical hematology routine.

, due to the discharge of three quarters of the untreated sewage generated, which leads to various water-borne diseases in humans.

METHODS The data of prepubertal patients who were hospitalized with vaginal discharge or bleeding treated in a provincial Grade III Level A Maternity and Children's Hospital from January 2012 to December 2018 were retrospectively reviewed.

A quinoline-derived titanium complex (TiQ) is shown here to possess remarkable photosensitizing properties when treated with an iodonium salt (Iod) to initiate, under visible light irradiation, (i) the free-radical photopolymerization of acrylate monomer in aerated/laminate conditions, (ii) the cationic photopolymerization of epoxy monomer under air, and (iii) the in situ formation of Ti-based nanoparticles (NPs) inside coatings.