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Journal of Clinical Oncology
Research Hotspot & Journal Scope - stage


Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.3501
Prospective pooled analysis of four randomized trials investigating duration of adjuvant (adj) oxaliplatin-based therapy (3 vs 6 months {m}) for patients (pts) with high-risk stage II colorectal cancer (CC).

Timothy Iveson · Alberto Sobrero · Takayuki Yoshino · Ioannis Sougklakos · Fang-Shu Ou · Jeffery P. Meyers · Qian Shi · Mark P Saunders · Roberto Labianca · Takeharu Yamanaka · Ioannis Boukovinas · Niels Henrik Hollander · Valter Torri · Kentaro Yamazaki · Vassilis Georgoulias · Sara Lonardi · Andrea Harkin · Gerardo Rosati · James Paul ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.8516
Ph1/2 study of Rova-T in combination with nivolumab (Nivo) ± ipilimumab (Ipi) for patients (pts) with 2L+ extensive-stage (ED) SCLC.

Jyoti Malhotra · Petros Nikolinakos · Ticiana Leal · Jonathan M. Lehman · Daniel Morgensztern · Jyoti D. Patel · John Wrangle · Giuseppe Curigliano · Eric Dansin · Laurent Greillier · Melissa L. Johnson · Neal Ready · Gilles Robinet · Satwant Lally · Shekman Wong · Emin Avsar · Ricardo Valenzuela · Charity D. Scripture · Giovanni Selvaggi · Benjamin Besse ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.4_SUPPL.487
Immunoscore clinical utility to identify good prognostic colon cancer stage II patients with high-risk clinico-pathological features for whom adjuvant treatment may be avoided.

Jérôme Galon · Fabienne Hermitte · Bernhard Mlecnik · Florence Marliot · Carlo Bifulco · Alessandro Lugli · Iris D. Nagtegaal · Arndt Hartmann · Marc Van den Eynde · Michael H. A. Roehrl · Pamela S. Ohashi · Eva Zavadova · Toshihiko Torigoe · Prabhudas S. Patel · Yili Wang · Yutaka Kawakami · Francesco M. Marincola · Paolo A. Ascierto · Bernard A. Fox · Franck Pagès ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.7_SUPPL.507
The PRIMETEST trial: Interim analysis of a phase II trial for primary retroperitoneal lymph node dissection (RPLND) in stage II A/B seminoma patients without adjuvant treatment.

Peter Albers · Andreas Hiester · Robert grosse Siemer · Achim Lusch ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/jco.2019.37.27_suppl.3
Effect of high patient out-of-pocket (OOP) cost for oral tyrosine kinase inhibitors (TKIs) on survival in EGFR and ALK positive stage IV non-small cell lung cancer (NSCLC).

Bernardo H. L. Goulart · Joseph M. Unger · Shasank Chennupati · Kathryn Egan · Catherine R. Fedorenko · Scott D. Ramsey ·

Medicine
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In the United States (US), the shift in the treatment paradigm following the introduction of second generation direct-acting antiviral (DAA) agents for hepatitis C virus (HCV) infection has favorably transformed the landscape of end-stage liver disease (ESLD) with a rapid decline in HCV-related liver transplantation; HCV had been the leading indication for liver transplantation for the last two decades (1).

Economic burden and healthcare utilization in nonalcoholic fatty liver disease. [10.21037/HBSN.2018.12.11]


Conclusions Critical limb ischemia was presented by patients with advanced age and high cardiovascular risk who were treated during severe and advanced stages where therapeutic options are limited.

Use of intravenous alprostadil in patients with severe critical ischemia of the lower limbs [10.1177/1708538118816267]


Tag-encoded pyrosequencing was used to examine bacterial and fungal community structure at five time points across one year corresponding to plant phenological stages.

Fungal and Bacterial Communities Exhibit Consistent Responses to Reversal of Soil Acidification and Phosphorus Limitation over Time. [10.3390/MICROORGANISMS8010001]


Cancer stage at diagnosis is an important determinant of survival, where earlier stages have significantly increased rates of survival.

The role of socioeconomic disparity in colorectal cancer stage at presentation [10.1007/s13304-019-00632-5]


We conclude that the differing degrees of isotopic variability observed for different elements in normal CAIs are the result of distinct carrier phases and that these CAIs were likely formed towards the final stages of homogenization of the large-scale isotopic heterogeneity that initially existed in the solar nebula.

Titanium isotope signatures of calcium-aluminum-rich inclusions from CV and CK chondrites: Implications for early Solar System reservoirs and mixing. [10.1016/J.GCA.2019.07.051]


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