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Journal of Clinical Oncology
Research Hotspot & Journal Scope - safety


Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.6008
Checkpoint inhibitors assessment in oropharynx cancer (CIAO): Safety and interim results.

Renata Ferrarotto · Diana Bell · M. Laura Rubin · Jiun-Kae Jack Lee · Jason Michael Johnson · Ryan P. Goepfert · Jack Phan · Yasir Elamin · Jeffrey N. Myers · Amy Clark Hessel · Faye M. Johnson · Maura L. Gillison · Andrew G. Sikora · Bonnie S. Glisson · Neil D. Gross ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.5024
Age-related efficacy and safety of apalutamide (APA) plus ongoing androgen deprivation therapy (ADT) in subgroups of patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC): Post hoc analysis of SPARTAN

Julie N. Graff · Matthew R. Smith · Fred Saad · Boris Hadaschik · Hiroji Uemura · Ji Youl Lee · Paul Mainwaring · David Olmos · Stéphane Oudard · Anil Londhe · Amitabha Bhaumik · Oliver Brendan Rooney · Angela Lopez-Gitlitz · Eric J. Small ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.8563
BIOLUMA: A phase II trial of nivolumab in combination with ipilimumab to evaluate efficacy and safety in lung cancer and to evaluate biomarkers predictive for response—Preliminary results from the SCLC cohort.

Rieke Fischer · Julie George · Andreas H. Scheel · Hans Anton Schloesser · Maria J.G.T. Vehreschild · Peter Brossart · Walburga Engel-Riedel · Frank Griesinger · Christian Grohé · Karl-Otto Kambartel · Jens Kern · Barbara Hermes · Kathrin Nachtkamp · Jens Panse · Martin Sebastian · Markus Lehmann · Rainer Wiewrodt · Reinhard Büttner · Roman K. Thomas · Juergen Wolf ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.8040
Efficacy and safety of daratumumab, bortezomib, and dexamethasone (D-Vd) in relapsed or refractory multiple myeloma (RRMM) based on cytogenetic risk: Updated subgroup analysis of CASTOR.

Katja Weisel · Andrew Spencer · Suzanne Lentzsch · Hervé Avet-Loiseau · Tomer M. Mark · Ivan Spicka · Alberto Bosi · Vania Tm Hungria · Michele Cavo · Je-Jung Lee · Ajay K. Nooka · Hang Quach · Markus Munder · Meral Beksac · Pieter Sonneveld · David Soong · Jon Ukropec · Ming Qi · Maria-Victoria Mateos ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.7_SUPPL.425
Avelumab treatment for metastatic urothelial carcinoma in the phase Ib JAVELIN Solid Tumor Study: Updated safety and efficacy analysis with ≥ two years of follow-up.

Andrea B. Apolo · John Allan Ellerton · Jeffrey R. Infante · Manish Agrawal · Michael S. Gordon · Raid Aljumaily · Carolyn D. Britten · Luc Dirix · Keun-Wook Lee · Matthew H. Taylor · Patrick Schöffski · Ding Wang · Alain Ravaud · Junyuan Xiong · Galit Rosen · James L. Gulley · Manish R. Patel ·

Medicine
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Stage 3 (evaluating the intervention) will involve: (i) a 12-month, two-arm, two-level cluster randomised controlled trial (1248 PHC professionals within 48 PHC centres; with randomisation at the centre level in a 1:1 ratio) to evaluate the impact of the intervention on patient safety culture (primary outcome), patient-reported safety experiences and outcomes (using the PREOS-PC survey), and avoidable hospitalisations; (ii) qualitative study with 20 PHC providers to evaluate the acceptability and perceived utility of the intervention and identify implementation barriers.

Development and evaluation of an intervention based on the provision of patient feedback to improve patient safety in Spanish primary healthcare centres: study protocol [10.1136/bmjopen-2019-031367]


Moreover, these agents are increasingly being recognized as a potential solution to the detection and biocontrol of various undesirable bacteria, which cause either spoilage of food materials, decreased microbiological safety of foods, or infectious diseases in food animals and crops.

Bacteriophages in Food Applications: From Foe to Friend. [10.1146/annurev-food-032818-121747]


BACKGROUND The present study aimed to evaluate safety of tranexamic acid (TA) administration and to assess bleeding risk in colorectal surgery (CRS).

The effects of tranexamic acid on blood loss and transfusion rate in colorectal surgery. [10.1016/j.amjsurg.2019.03.013]


Conclusions The application of detailed nursing in anesthesia recovery room nursing can reduce the incidence of complications and adverse events during anesthesia recovery, improve nursing satisfaction, ensure the perioperative safety of patients, and accelerate recovery and postoperative recovery.

Application effect of detail management in anesthesia recovery nursing [10.3760/CMA.J.ISSN.1673-4351.2019.13.032]


My case highlights the importance of appropriate safety netting,1 rare diseases,2 unintentional weight loss,3 and reassurance.

The stable rower: identifying a rare disease. [10.3399/bjgp19X701117]


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