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Journal of Clinical Oncology
Research Hotspot & Journal Scope - population


Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.2587
Real-world outcomes of underrepresented patient populations treated with immune checkpoint inhibitors (ICIs): African American descent, poor ECOG performance status, and chronic viral infections.

Neil J. Shah · Matthew Blackburn · Michael R. Cook · Anas Belouali · Michael Serzan · William J Kelly · Athanasios Bikas · Chul Kim · Subha Madhavan · Stephen V. Liu · Michael B. Atkins ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.E13122
Large cell neuroendocrine carcinoma of the lung: A population-based study.

Connor J. Kinslow · Michael S. May · Tony J. C. Wang · Simon K. Cheng ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.E12046
Oncotype DX DCIS use and clinical utility: A SEER population-based study.

Yao Yuan · Alison L. Van Dyke · Allison W. Kurian · Serban Negoita · Valentina I. Petkov ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.1041
Interim results from the full population of the phase 3b CompLEEment-1 study of ribociclib (RIBO) plus letrozole (LET) in the treatment of HR+/HER2– advanced breast cancer (ABC).

Michelino DeLaurentiis · Simona Borstnar · Mario Campone · Ellen Warner · Salvador Bofill · William Jacot · Susan Dent · Miguel Martín · Alistair Ring · Paul Cottu · Janice M. Lu · Eva Ciruelos · Hamdy A. Azim · Sanjoy Chatterjee · K Zhou · J Wu · Nii Ankrah · Claudio Zamagni ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.7_SUPPL.268
Racial disparities in radium-223 treatment in a large real-world population.

Hanson Zhao · Lauren E. Howard · Amanda De Hoedt · Martha Kennedy Terris · Christopher L. Amling · Christopher J. Kane · Matthew R. Cooperberg · William J. Aronson · Thomas J. Polascik · Stephen J. Freedland ·

Medicine
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ConclusionsIn a non-selected population of examinees taking summative exams, long-menu questions have the same discriminatory power as classic Type A questions, but they are slightly more difficult.

Comparison of long-menu and single-best-answer multiple choice questions in computer-based summative assessments: a randomised controlled trial [10.1186/s12909-019-1651-6]


China also has the largest population at high risk of stroke, and risk factor control is much lower than that of developed countries in Europe and America.

Advanced clinical education for stroke physicians in China: The ACTION and SCA models [10.1177/1747493018816515]


These strategies allow robust analysis and isolation of mitochondrial subpopulations to more broadly elucidate the underlying complexities of mitochondria as these organelles function collectively within a cell.

A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics. [10.1038/s42003-019-0513-4]


Figure 1 Observed and Model Predicted Percentage of Subjects Experiencing Laboratory Changes/Safety Events of Interest with Increasing UPA Plasma ExposuresTable 1 Model-Estimated Efficacy Responses Following Placebo and UPA 15 mg and 30 mg QD Dosing Regimens Based on Exposure-Response Analyses of Phase 2 and 3 Studies Population Clinical Efficacy Response Variablea Upadacitinib Dose Placebo 15 mg QD 30 mg QD csDMARD-IR on Background csDMARDs ACR20 40 (34, 47) 66 (59, 71) 68 (63, 74) ACR50 17 (12, 22) 41 (35, 47) 45 (39, 51) ACR70 6 (3, 11) 23 (17, 29) 26 (21, 33) DAS28(CRP) ≤ 3.

FRI0138 EXPOSURE-RESPONSE ANALYSES OF UPADACITINIB EFFICACY AND SAFETY IN RHEUMATOID ARTHRITIS – ANALYSES OF PHASE 2 AND 3 STUDIES [10.1136/annrheumdis-2019-eular.752]


Background and objectives Nonsuicidal self-injury (NSSI) is most common in adolescent populations whose prevalence is continuously increasing.

Psychopathology and Patterns of Sensory Processing In Non-suicidal Self-Injured Adolescents: Insights from Neuropsychological and Neurophysiological Studies [10.4172/NEUROPSYCHIATRY.1000579]


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