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Journal of Clinical Oncology
Research Hotspot & Journal Scope - colorectal


Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.3501
Prospective pooled analysis of four randomized trials investigating duration of adjuvant (adj) oxaliplatin-based therapy (3 vs 6 months {m}) for patients (pts) with high-risk stage II colorectal cancer (CC).

Timothy Iveson · Alberto Sobrero · Takayuki Yoshino · Ioannis Sougklakos · Fang-Shu Ou · Jeffery P. Meyers · Qian Shi · Mark P Saunders · Roberto Labianca · Takeharu Yamanaka · Ioannis Boukovinas · Niels Henrik Hollander · Valter Torri · Kentaro Yamazaki · Vassilis Georgoulias · Sara Lonardi · Andrea Harkin · Gerardo Rosati · James Paul ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.4_SUPPL.581
The relationship between tumor budding, tumor microenvironment, and survival in patients with primary operable colorectal cancer.

Hester C. van Wyk · Antonia K. Roseweir · Ditte Anderson · Elizabeth J. Sutton · Paul G. Horgan · Donald C. McMillan · Joanne Edwards ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.4_SUPPL.637
Randomized study evaluating trifluridine/tipiracil (TAS-102) versus + trifluridine/tipiracil + bevacizumab as last-line therapy in patients with chemorefractory unresectable metastatic colorectal cancer (mCRC).

Per Pfeiffer · Mette Karen Yilmaz · Søren Møller · Line Maltha · Merete Krogh · Daniela Zitnjak · Caroline Lemb Szameitat · Finn Hejlesen · Karina Gravgaard Thomsen · Camilla Qvortrup ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.4_SUPPL.596
Activity of EGFR inhibition in atypical (non-V600E) BRAF-mutated metastatic colorectal cancer.

Benny Johnson · Jonathan M. Loree · Van Karlyle Morris · Arvind Dasari · Shubham Pant · Kanwal Pratap Singh Raghav · Scott Kopetz ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.E15084
Analytical and clinical validation of a novel amplicon-based NGS assay for evaluation of circulating tumor DNA in metastatic colorectal cancer patients.

Beili Wang · Shengchao Wu · Fei Huang · Min-Na Shen · Huiqin Jiang · Yiyi Yu · Qian Yu · Yihui Yang · Ying Zhao · Yiwen Zhou · Baishen Pan · Tianshu Liu · Wei Guo ·

Medicine
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BACKGROUND The prevalence and clinical implications of genetic heterogeneity in patients with multiple colorectal liver metastases remain largely unknown.

High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases. [10.1016/j.clcc.2019.09.003]


Overall survival (OS) and disease-free survival (DFS) according to FH of CRC or colorectal neoplasm were evaluated using Cox proportional hazards regression and Kaplan–Meier curve.

Association of Family History With Cancer Recurrence, Survival, and the Incidence of Colorectal Adenoma in Patients With Colorectal Cancer [10.15430/JCP.2019.24.1.1]


Background Little is known about metastatic patterns in patients with obstructing colorectal cancer (CRC).

Differences in Metastatic Pattern in Patients Presenting With or Without Obstructing Colorectal Cancer: A Retrospective Observational Study of 2595 Patients [10.1245/s10434-019-08119-8]


However, T1 colorectal cancer in the tattooing group had significantly higher adequate LNH (91.

Efficacy of preoperative colonoscopic tattooing with indocyanine green on lymph node harvest and factors associated with inadequate lymph node harvest in colorectal cancer [10.1080/00365521.2019.1612940]


BRAF inhibitors synergize with BH3 mimetics to induce apoptosis in BRAF mutant colorectal cancer cells [abstract].

Abstract 2492: BRAF inhibitors synergize with BH3 mimetics to induce apoptosis in BRAF mutant colorectal cancer cells [10.1158/1538-7445.AM2019-2492]


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