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Journal of Clinical Oncology
Research Hotspot & Journal Scope - cancers


Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.5005
TOPARP-B: A phase II randomized trial of the poly(ADP)-ribose polymerase (PARP) inhibitor olaparib for metastatic castration resistant prostate cancers (mCRPC) with DNA damage repair (DDR) alterations

Joaquin Mateo · Nuria Porta · U. McGovern · Tony Elliott · Robert Jones · Isabel Syndikus · Christy Ralph · Suneil Jain · Mohini Varughese · O. Parikh · Simon J. Crabb · Susana Miranda · George Seed · Claudia Bertan · Aude Espinasse · Peter Chatfield · Diletta Bianchini · Emma Hall · Suzanne Carreira · Johann S. de Bono ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.6018
Activity and tolerability of BLU-667, a highly potent and selective RET inhibitor, in patients with advanced RET-altered thyroid cancers.

Matthew H. Taylor · Justin F. Gainor · Mimi I-Nan Hu · Viola W. Zhu · Gilberto Lopes · Sophie Leboulleux · Marcia S. Brose · Martin Schuler · Daniel W. Bowles · Dong-Wan Kim · Christina S. Baik · Elena Garralda · Chia-Chi Lin · Douglas Adkins · Debashis Sarker · Giuseppe Curigliano · Hui Zhang · Corinne Clifford · Christopher D. Turner · Vivek Subbiah ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.TPS5091
IMPACT: Immunotherapy in patients with metastatic cancers and CDK12 mutations.

Melissa Andrea Reimers · Wassim Abida · Jonathan Chou · Daniel J. George · Elisabeth I. Heath · Rana R. McKay · Russell Pachynski · Jingsong Zhang · Jae Eun Choi · Felix Y. Feng · Gina M. Neshewat · Marcin Cieslik · Stephanie Daignault-Newton · Eric J. Small · Arul M. Chinnaiyan · Ajjai Alva ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.4_SUPPL.60
Association of DNA damage response and repair genes (DDR) mutations and microsatellite instability (MSI), PD-L1 expression, tumor mutational burden (TMB) in gastroesophageal cancers.

Michael Cerniglia · Joanne Xiu · Axel F Grothey · Michael J. Pishvaian · Jimmy J. Hwang · John Marshall · Ari M. Vanderwalde · Anthony F. Shields · Heinz-Josef Lenz · Mohamed E. Salem · Philip A. Philip · Richard M. Goldberg · W. Michael Korn · Sunnie S. Kim ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.4_SUPPL.TPS179
bTMB-High Basket trial: A multicenter phase II trial of nivolumab monotherapy in patients with advanced gastrointestinal cancers with high blood tumor mutational burden (bTMB).

Yoshiaki Nakamura · Yoshito Komatsu · Ken Kato · Eiji Shinozaki · Hideaki Bando · Takeshi Kato · Tomohiro Nishina · Taito Esaki · Shogo Nomura · Gakuto Ogawa · Ayako Sugama · Miki Fukutani · Akihiro Sato · Justin I. Odegaard · Takeshi Kuwata · Kouji Matsushima · Tetsuya Nakatsura · Hiromichi Nakajima · Takayuki Yoshino ·

Medicine
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Purpose: The genesis of all cancers results from an accumulation of mutations, constitutional and/or acquired when induced by external mutagenic factors.

A Constitutional Activating MET Mutation Makes the Genetic Link between Malignancies and Chronic Inflammatory Diseases [10.1158/1078-0432.CCR-18-3261]


Sarcomas are rare cancers derived from mesenchymal tissues.

Abstract 292: PTC596 combination therapy for sarcoma [10.1158/1538-7445.AM2019-292]


Received: 10 December 2019 Accepted: 25 December 2019 Today’s, of the major cancers for both females and male is lung cancer.

Diagnosing Lung Cancer Using Grasshopper Optimization Algorithm and k-Nearest Neighbor Classification [10.18280/rces.060401]


Conclusions The estimate of the incidence of cancers attributable to infectious agents in Italy in 2018 (7.

Estimates of the incidence of infection-related cancers in Italy and Italian regions in 2018 [10.15167/2421-4248/jpmh2019.60.4.1434]


Objectives To determine from the perspective of the State of Texas, the direct medical care costs associated with cervical, vaginal, and vulvar cancers in Texas Medicaid enrollees.

Cervical, Vaginal, and Vulvar Cancer Costs Incurred by the Medicaid Program in Publicly Insured Patients in Texas [10.1097/LGT.0000000000000472]


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