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Journal of Clinical Oncology
Research Hotspot & Journal Scope - cancer


Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.8503
Neoadjuvant atezolizumab in resectable non-small cell lung cancer (NSCLC): Interim analysis and biomarker data from a multicenter study (LCMC3).

David J. Kwiatkowski · Valerie W. Rusch · Jamie E. Chaft · Bruce E. Johnson · Alan Nicholas · Ignacio Ivan Wistuba · Robert E. Merritt · Jay M. Lee · Paul A. Bunn · Yan Tang · See-Chun Phan · Saiama N. Waqar · Alexander Patterson · Eric B. Haura · Eric M. Toloza · Karen L. Reckamp · Dan J. Raz · Katja Schulze · Ann M. Johnson · David P. Carbone ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.18.02309
Neoadjuvant Modified FOLFOX6 With or Without Radiation Versus Fluorouracil Plus Radiation for Locally Advanced Rectal Cancer: Final Results of the Chinese FOWARC Trial

Yanhong Deng · Pan Chi · Ping Lan · Lei Wang · Weiqing Chen · Long Cui · Daoda Chen · Jie Cao · Hongbo Wei · Xiang Peng · Zonghai Huang · Guanfu Cai · Ren Zhao · Zhongcheng Huang · Lin Xu · Hongfeng Zhou · Yisheng Wei · Hao Zhang · Jian Zheng · Yan Huang · Zhiyang Zhou · Yue Cai · Liang Kang · Meijin Huang · Xiaojian Wu · Junsheng Peng · Donglin Ren · Jianping Wang ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.5005
TOPARP-B: A phase II randomized trial of the poly(ADP)-ribose polymerase (PARP) inhibitor olaparib for metastatic castration resistant prostate cancers (mCRPC) with DNA damage repair (DDR) alterations

Joaquin Mateo · Nuria Porta · U. McGovern · Tony Elliott · Robert Jones · Isabel Syndikus · Christy Ralph · Suneil Jain · Mohini Varughese · O. Parikh · Simon J. Crabb · Susana Miranda · George Seed · Claudia Bertan · Aude Espinasse · Peter Chatfield · Diletta Bianchini · Emma Hall · Suzanne Carreira · Johann S. de Bono ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.6018
Activity and tolerability of BLU-667, a highly potent and selective RET inhibitor, in patients with advanced RET-altered thyroid cancers.

Matthew H. Taylor · Justin F. Gainor · Mimi I-Nan Hu · Viola W. Zhu · Gilberto Lopes · Sophie Leboulleux · Marcia S. Brose · Martin Schuler · Daniel W. Bowles · Dong-Wan Kim · Christina S. Baik · Elena Garralda · Chia-Chi Lin · Douglas Adkins · Debashis Sarker · Giuseppe Curigliano · Hui Zhang · Corinne Clifford · Christopher D. Turner · Vivek Subbiah ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.1005
Capivasertib (AZD5363) plus fulvestrant versus placebo plus fulvestrant after relapse or progression on an aromatase inhibitor in metastatic ER-positive breast cancer (FAKTION): A randomized, double-blind, placebo-controlled, phase II trial.

Robert Hugh Jones · Margherita Carucci · Angela C. Casbard · Rachel Butler · Fouad S Alchami · Catherine Jane Bale · Pavel Bezecny · Johnathan Joffe · Sarah Moon · Chris Twelves · Ramachandran Venkitaraman · Simon Waters · Sacha J Howell ·

Medicine
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Hepatic and pancreatobiliary cancers often present at advanced stages, and currently, there are very few approved therapeutic options.

Predictive Biomarkers and Targeted Therapies in Hepatic, Pancreatic, and Biliary Cancers [10.1007/978-3-319-95228-4_40]


Early detection of ovarian cancer promises to reduce mortality.

Osteopontin, Macrophage Migration Inhibitory Factor and Anti-Interleukin-8 Autoantibodies Complement CA125 for Detection of Early Stage Ovarian Cancer [10.3390/cancers11050596]


0, and reproductive concerns, assessed with the Reproductive Concerns After Cancer scale.

Sexual Dysfunction and Reproductive Concerns in Young Men Diagnosed With Testicular Cancer: An Observational Study. [10.1016/j.jsxm.2019.05.005]


Last colorectal cancer ESMO guidelines do not recommend testing DPD deficient up front.

Dihydropyrimidine dehydrogenase (DPD) determination prior the administration of medicines containing fluorouracil: A single Spanish hospital experience [10.1093/annonc/mdz246.070]


Oral mucositis (OM) is a common complication in cancer patients undergoing anticancer treatment.

Regulation of HMGB1 release protects chemoradiotherapy-associated mucositis [10.1038/s41385-019-0132-x]


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