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Journal of Clinical Oncology
Research Hotspot & Journal Scope - burden


Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.4085
Frequency of BRCA mutation in biliary tract cancer and its correlation with tumor mutational burden (TMB) and microsatellite instability (MSI).

Gilbert Spizzo · Alberto Puccini · Joanne Xiu · Richard M. Goldberg · Axel F Grothey · Anthony F. Shields · Sukeshi Patel Arora · Moh’d Khushman · Mohamed E. Salem · Francesca Battaglin · Wafik S. El-Deiry · Ryuma Tokunaga · Philip A. Philip · Michael J. Hall · John L. Marshall · Florian Kocher · Wolfgang Michael Korn · Heinz-Josef Lenz · Andreas Seeber ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.4_SUPPL.60
Association of DNA damage response and repair genes (DDR) mutations and microsatellite instability (MSI), PD-L1 expression, tumor mutational burden (TMB) in gastroesophageal cancers.

Michael Cerniglia · Joanne Xiu · Axel F Grothey · Michael J. Pishvaian · Jimmy J. Hwang · John Marshall · Ari M. Vanderwalde · Anthony F. Shields · Heinz-Josef Lenz · Mohamed E. Salem · Philip A. Philip · Richard M. Goldberg · W. Michael Korn · Sunnie S. Kim ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.E16079
Characterization of tumor mutational burden (TMB), PD-L1, and DNA repair genes to assess correlation with immune checkpoint inhibitors (ICIs) response in metastatic renal cell carcinoma (mRCC).

Matthew Labriola · Jason Zhu · Rajan T. Gupta · Shannon McCall · Jennifer Jackson · James R. White · Elizabeth Weingartner · Eric Kong · Peter Simone · Eniko Papp · Kelly Gerding · John K. Simmons · Daniel J. George · Tian Zhang ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.4_SUPPL.TPS179
bTMB-High Basket trial: A multicenter phase II trial of nivolumab monotherapy in patients with advanced gastrointestinal cancers with high blood tumor mutational burden (bTMB).

Yoshiaki Nakamura · Yoshito Komatsu · Ken Kato · Eiji Shinozaki · Hideaki Bando · Takeshi Kato · Tomohiro Nishina · Taito Esaki · Shogo Nomura · Gakuto Ogawa · Ayako Sugama · Miki Fukutani · Akihiro Sato · Justin I. Odegaard · Takeshi Kuwata · Kouji Matsushima · Tetsuya Nakatsura · Hiromichi Nakajima · Takayuki Yoshino ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.E23159
Tumor mutation burden and depression in lung cancer: Association with inflammation.

Daniel C. McFarland · Devika R. Jutagir · Barry Rosenfeld · Andrew H. Miller · Christian J. Nelson · William Breitbart ·

Medicine
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Family burden measured using the Zarit Burden Interview, while the depression measured using Beck Depression Inventory-II.

Hubungan Beban Dengan Depresi pada Keluarga yang Merawat Pasien Stroke [10.17509/jpki.v5i2.19821]


To elucidate the involvement of MERTK inhibitor in tumor, the tumor mutation burden, tumor microenvironment and immune cell phenotype were deconvoluted.

Abstract 4081: Efficacy of MERTK inhibitor in combination with pembrolizumab in lung cancer [10.1158/1538-7445.AM2019-4081]


Substantial sex-based differences exist in the inpatient burden of AYA CM.

National Burden of Hospitalization Due to Cutaneous Melanoma in Adolescents and Young Adults [10.1097/COC.0000000000000605]


Methods We trained 86 nurses and counsellors in 56 public health facilities in six high HIV burden Districts in 2017 to provide index partner/child testing (tracing and testing of partners/children of people living with HIV).

HIV positivity and referral to treatment following index testing of partners and children of HIV-infected patients in public sector facilities in South Africa [10.1097/QAI.0000000000002048]


Background: Injury surveillance has been used to quantify the scope of the injury burden in Australian football.

Australian Football League Injury Characteristics Differ Between Matches and Training: A Longitudinal Analysis of Changes in the Setting, Site, and Time Span From 1997 to 2016 [10.1177/2325967119837641]


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