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Journal of Clinical Oncology
Research Hotspot & Journal Scope - Phase


Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.5005
TOPARP-B: A phase II randomized trial of the poly(ADP)-ribose polymerase (PARP) inhibitor olaparib for metastatic castration resistant prostate cancers (mCRPC) with DNA damage repair (DDR) alterations

Joaquin Mateo · Nuria Porta · U. McGovern · Tony Elliott · Robert Jones · Isabel Syndikus · Christy Ralph · Suneil Jain · Mohini Varughese · O. Parikh · Simon J. Crabb · Susana Miranda · George Seed · Claudia Bertan · Aude Espinasse · Peter Chatfield · Diletta Bianchini · Emma Hall · Suzanne Carreira · Johann S. de Bono ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.1005
Capivasertib (AZD5363) plus fulvestrant versus placebo plus fulvestrant after relapse or progression on an aromatase inhibitor in metastatic ER-positive breast cancer (FAKTION): A randomized, double-blind, placebo-controlled, phase II trial.

Robert Hugh Jones · Margherita Carucci · Angela C. Casbard · Rachel Butler · Fouad S Alchami · Catherine Jane Bale · Pavel Bezecny · Johnathan Joffe · Sarah Moon · Chris Twelves · Ramachandran Venkitaraman · Simon Waters · Sacha J Howell ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.15_SUPPL.9000
RELAY: A multinational, double-blind, randomized Phase 3 study of erlotinib (ERL) in combination with ramucirumab (RAM) or placebo (PL) in previously untreated patients with epidermal growth factor receptor mutation-positive (EGFRm) metastatic non-small cell lung cancer (NSCLC).

Kazuhiko Nakagawa · Edward B. Garon · Takashi Seto · Makoto Nishio · Santiago Ponce Aix · Chao-Hua Chiu · Keunchil Park · Silvia Novello · Ernest Nadal · Fumio Imamura · Kiyotaka Yoh · Jin-Yuan Shih · Kwok Hung Au · Denis Moro-Sibilot · Sotaro Enatsu · Annamaria Zimmermann · Bente Frimodt-Moller · Carla M. Visseren Grul · Martin Reck ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.2019.37.4_SUPPL.129
Phase I/II study of ramucirumab plus nivolumab in patients in second-line treatment for advanced gastric adenocarcinoma (NivoRam study).

Hiroki Hara · Hirokazu Shoji · Daisuke Takahari · Taito Esaki · Nozomu Machida · Kengo Nagashima · Kazunori Aoki · Kazufumi Honda · Takahiro Miyamoto · Narikazu Boku · Ken Kato ·

Medicine
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Journal of Clinical Oncology - DOI: 10.1200/JCO.19.01507
Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer

Carryn M Anderson · Christopher M Lee · Deborah P Saunders · Amarinthia Curtis · Neal Dunlap · Chaitali Nangia · Arielle S Lee · Sharon M Gordon · Philip Kovoor · Roberto Arevalo-Araujo · Voichita Bar-Ad · Abhinand Peddada · Kyle Colvett · Douglas Miller · Anshu K Jain · James Wheeler · Dukagjin Blakaj · Marcelo Bonomi · Sanjiv S Agarwala · Madhur Garg · Francis Worden · Jon Holmlund · Jeffrey M Brill · Matt Downs · Stephen T Sonis · Sanford Katz · John M Buatti ·

Medicine
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Free adenosine monophosphate also induces the opposite chiral twist both in the bulk nematic phase as shown by induced thin film circular dichroism spectropolarimetry and in the tactoids in comparison to adenosine monophosphate bound to the gold nanocluster.

Amplification of Chirality by Adenosine Monophosphate-Capped Luminescent Gold Nanoclusters in Nematic Lyotropic Chromonic Liquid Crystal Tactoids [10.1021/ACSOMEGA.8B03335]


184(TCBA)(H2O)2]2·DMF emits bright white light when excited at 380 nm and could potentially be used as single-phase white light-emitting diode phosphors materials.

A Robust TbIII-MOF for Ultrasensitive Detection of Trinitrophenol: Matched Channel Dimensions and Strong Host-Guest Interactions. [10.1021/acs.inorgchem.9b01008]


It is done with the Time series Analysis to find the optimal Mean temperature for multiple phases (fifteen to thirty days seasonal period of Daily Temperature).

Architecture for Interactive Internet of Things to Estimate Optimal Mean Temperature with Multiphase in Crop Insurance Payout System [10.1109/I-SMAC47947.2019.9032579]


This tunability originates from the effective change in local dielectric properties of the VO2 sublayer in the course of the temperature-tuned insulator-to-metal phase transition.

Phase-Change Hyperbolic Heterostructures for Nanopolaritonics: A Case Study of hBN/VO2. [10.1002/adma.201900251]


Four-dimensional phase computed tomography (4D phase CT) by an X-ray Talbot interferometer (XTI) with white synchrotron radiation has ever been demonstrated at a temporal resolution of about 1 s for soft-matter samples.

Development of pink-beam 4D phase CT for in-situ observation of polymers under infrared laser irradiation [10.1038/s41598-019-43589-6]


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