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Frontiers of Hormone Research
Research Hotspot & Journal Scope - Severe


Frontiers of Hormone Research - DOI: 10.1159/000491038
Familial Hypocalciuric Hypercalcemia and Neonatal Severe Hyperparathyroidism.

Letizia Vannucci · Maria Luisa Brandi ·

Biology Medicine
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Frontiers of Hormone Research - DOI: 10.1159/000494911
Androgens and Severe Insulin Resistance States: Basic and Clinical Aspects.

Alessandra Gambineri · Laura Zanotti · Daniela Ibarra-Gasparini ·

Medicine
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Purpose To analyse the influence of renal function on the outcomes of vitrectomy for tractional-related complications in cases of severe proliferative diabetic retinopathy (PDR).

Surgical outcomes of vitrectomy surgery for proliferative diabetic retinopathy in patients with abnormal renal function [10.1007/s00417-019-04532-7]


Both aborted fetuses had pterygium, severe arthrogryposis, and fetal hydrops with cystic hygroma, being compatible with LMPS.

Utilization of Whole Exome Sequencing in Lethal Form of Multiple Pterygium Syndrome: Identification of Mutations in Embryonal Subunit of Acetylcholine Receptor [10.22088/IJMCM.BUMS.8.4.258]


We present a case of an 11-month-old girl with severe pectus excavatum who presented with a 3-day history of increasing dyspnea which was present since her birth.

Minimally invasive repair of the severe pectus excavatum in an infant [10.1016/J.EPSC.2019.101246]


Physical examination revealed severe dehydration (10%) and high temperature, besides the abdominal enlargement.

Pyometra in a bitch possibly caused by simultaneous administration of levonorgestrel and estradiol cypionate. [10.22456/1679-9216.95875]


METHODS In this descriptive observational study, we included consecutive patients aged at least 18 years with grade 2 or worse haem-irAEs induced by anti-PD-1 or anti-PD-L1 immunotherapy registered in three French pharmacovigilance databases: the Registre des Effets Indésirables Sévères des Anticorps Monoclonaux Immunomodulateurs en Cancérologie (REISAMIC; a prospective registry of patients treated with anti-PD-1 or anti-PD-L1 at a single centre), the ImmunoTOX committee of Gustave Roussy (a national referral database of suspected irAEs in patients treated with immunotherapy), and the registry of the Centre de Référence des Cytopénies Auto-Immunes de l'Adulte (CeReCAI; a national database of autoimmune cytopenias).

Haematological immune-related adverse events induced by anti-PD-1 or anti-PD-L1 immunotherapy: a descriptive observational study. [10.1016/S2352-3026(18)30175-3]


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