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European Journal of Integrative Medicine
Research Hotspot & Journal Scope - cholesterol


European Journal of Integrative Medicine - DOI: 10.1016/J.EUJIM.2019.05.001
The effect of green coffee extract supplementation on serum oxidized LDL cholesterol and total antioxidant capacity in patients with dyslipidemia: A randomized, double-blind, placebo-controlled trial

Shekoufeh Salamat · Saeid Sadeghian Sharif · Ali Nazary-Vanani · Hamed Kord-Varkaneh · Cain C.T. Clark · Majid Mohammadshahi ·

Medicine
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European Journal of Integrative Medicine - DOI: 10.1016/J.EUJIM.2019.05.005
Detection of serum high-density lipoprotein cholesterol high levels in monks practicing Samatha and Vipassana meditation

Widuranga Kumbukgolla · Jayaweera Arachchige Asela Sampath Jayaweera · Ponnamperuma Aratchige Jayasumana Perera · Sigi Hale ·

Medicine
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The imbalance in intracellular cholesterol resulted by IL-1β can in turn transform HMCs into foam cells and aggravate glomerulosclerosis.

Interleukin-1β Regulates Lipid Homeostasis in Human Glomerular Mesangial Cells [10.1007/s12603-019-1302-y]


In this study, we aim to develop a safer and faster strategy using fluorescent labelled-cholesterol (NBD-cholesterol) in a cellular assay to trace the cholesterol uptake and efflux process in THP-1-derived macrophages.

High-throughput Nitrobenzoxadiazole-labeled Cholesterol Efflux Assay. [10.3791/58891]


In comparison with the urban areas, the subjects in rural regions showed the higher level of blood pressure, serum triglyceride, and LDL-cholesterol levels (P < 0.

Dietary Diversity Is Associated with the Risk of Hypertension in Rural and Urban Middle-aged Koreans (P18-074-19). [10.1093/cdn/nzz039.P18-074-19]


The serum and hepatic cholesterol were tested, the mRNA and protein expression levels of Niemann-Pick C1-Like 1 (NPC1L1), liver X receptor-α (LXR-α) and the ATP-binding cassette G5/G8 (ABCG5/G8) transporters were measured.

Diosgenin regulates cholesterol metabolism in hypercholesterolemic rats by inhibiting NPC1L1 and enhancing ABCG5 and ABCG8. [10.1016/j.bbalip.2019.04.010]


Using drug-mediated cholesterol extraction along with viral entry and K+ uptake assays, we report three major findings: BUNV and HAZV require cellular cholesterol during endosomal escape; cholesterol depletion from host cells impairs K+ accumulation in maturing endosomes, revealing new insights into endosomal K+ homeostasis; and “priming” BUNV and HAZV virions with K+ before infection alleviates their cholesterol requirement.

Cellular cholesterol abundance regulates potassium accumulation within endosomes and is an important determinant in bunyavirus entry [10.1074/jbc.RA119.007618]


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