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Endocrine Pathology
Research Hotspot & Journal Scope - V600E


Endocrine Pathology - DOI: 10.1007/s12022-019-09585-2
A Systematic Review and Meta-Analysis of the Diagnostic Performance of BRAF V600E Immunohistochemistry in Thyroid Histopathology

Ranjit Singarayer · Ozgur Mete · Laure Perrier · Lehana Thabane · Sylvia L. Asa · Stan Van Uum · Shereen Ezzat · David P. Goldstein · Anna M. Sawka ·

Medicine
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Endocrine Pathology - DOI: 10.1007/s12022-019-09596-z
Testing for BRAF (V600E) Mutation in Thyroid Nodules with Fine-Needle Aspiration (FNA) Read as Suspicious for Malignancy (Bethesda V, Thy4, TIR4): a Systematic Review and Meta-analysis

Pierpaolo Trimboli · Lorenzo Scappaticcio · Giorgio Treglia · Leo Guidobaldi · Massimo Bongiovanni · Luca Giovanella ·

Medicine
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Endocrine Pathology - DOI: 10.1007/s12022-019-09591-4
The Role of BRAF V600E in Reducing AUS/FLUS Diagnosis in Thyroid Fine Needle Aspiration

Lei Yin · Yi Tang · Shanshan Yu · Chenglong Wang · Ming Xiao · Yalan Wang · Shu Jun Liu · Lu Gao · Keli Huang · Ling Jin ·

Medicine
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MLH1 promoter methylation and V600E BRAF mutation analysis were investigated on 61 CRCs.

Universal screening to identify Lynch syndrome: two years of experience in a Northern Italian Center [10.1097/CEJ.0000000000000543]


The aims of our study were to detect BRAFV600E mutations within circulating cell-free DNA in plasma ("liquid biopsy") by a droplet digital PCR (ddPCR) method, and to investigate how well the Breslow-Clark score can be predicted by ddPCR.

Detection of BRAFV600E Mutation in Melanoma Patients by Digital PCR of Circulating DNA. [10.1089/gtmb.2018.0193]


In contrast to metastatic melanoma, BRAF inhibition alone or in combination with mitogen-activated protein kinase kinase (MEK) inhibitors has shown little utility in the treatment of BRAF V600E-mutant mCRC.

Binimetinib, encorafenib and cetuximab (BEACON Trial) combination therapy for patients with BRAF V600E-mutant metastatic colorectal cancer. [10.1358/dot.2019.55.11.3035584]


The aims of our study were to detect BRAFV600E mutations within circulating cell-free DNA in plasma ("liquid biopsy") by a droplet digital PCR (ddPCR) method, and to investigate how well the Breslow-Clark score can be predicted by ddPCR.

Detection of BRAFV600E Mutation in Melanoma Patients by Digital PCR of Circulating DNA. [10.1089/gtmb.2018.0193]


1 The disease is believed to progress despite smoking cessation due to a BRAF-V600E mutation.

RECURRENT PNEUMOTHORACES IN A YOUNG SMOKER WITH RAPIDLY PROGRESSIVE LANGERHAN’S HISTIOCYTOSIS [10.1016/j.chest.2019.08.1161]



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