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Circulation. Cardiovascular quality and outcomes
Research Hotspot & Journal Scope - Inhibitors

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Circulation. Cardiovascular quality and outcomes - DOI: 10.1161/CIRCOUTCOMES.118.005404

Effect of Access to Prescribed PCSK9 Inhibitors on Cardiovascular Outcomes

Kelly D Myers · Niloofar Farboodi · Mkaya Mwamburi · William Howard · David Staszak · Samuel Gidding · Seth J Baum · Katherine Wilemon · Daniel J Rader ·

Medicine
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Circulation. Cardiovascular quality and outcomes - DOI: 10.1161/CIRCOUTCOMES.119.005910

PCSK9 Inhibitors Prior Authorization.

Khurram Nasir · Suveen Angraal · Salim S Virani ·

Medicine
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Several potent and selective small-molecule inhibitors targeting CBP BrD have been reported, but thus far small-molecule inhibitors targeting BrD outside of the BrD and extraterminal domain (BET) family are especially lacking.

We determined whether 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A (HMG‐CoA) reductase inhibitors—statins, commonly prescribed to patients at risk of heart failure (HF)—can de‐differentiate myofibroblasts, alter cellular bioenergetics, and impact the human ventricular fibroblasts (hVFs) in HF patients.

Patients taking SGLT-2 inhibitors were excluded because of the potential effect on circulating acetoacetate levels.

Background/aim Tumour necrosis factor inhibitors and anti-interleukin-6 (anti-IL-6) therapies are increasingly being used in Takayasu’s arteritis (TA) patients who are unresponsive to corticosteroids ± conventional immunosuppressive agents.

Compounds covered include glycine site agonists, glycine and system A-type transporter inhibitors, d-amino acid oxidase inhibitors, memantine and nicotinic alpha-7 acetylcholine receptor agonists.

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Research Hotspot

Circulation. Cardiovascular quality and outcomes

Research Hotspot

Journal Scope

Circulation. Cardiovascular quality and outcomes

Journal Scope

Patients Cardiovascular Acute Outcomes Myocardial Coronary Disease Infarction Clinical Randomized Heart Data Intervention Performance Trial Survival Adults Quality Percutaneous Blood Stroke Risk Health Systematic Therapy Long-Term Pressure Control Prediction Implantable Trials Mortality Older Association Hospital Cardiac Arrest Associated Patient Review Utilization Results Veterans Assessment Tracking United States Comparative Models Model Neural Networks Detection Failure Differences Practice Dog Ownership Meta-Analysis Integrating Controlled Trends Ischemic Standard Thirty-Day Readmission Hospitalized Effect PCSK9 Inhibitors Evidence Fragility Index Out-of-Hospital Examining Impact Automated Rates Physician Chronic Total Analysis Versus Anticoagulation Deep Treatment Measures Research Atrial Fibrillation Learning

Research Scope

Circulation. Cardiovascular quality and outcomes

Research Scope

Patients Cardiovascular Acute Outcomes Myocardial Coronary Disease Infarction Clinical Randomized Heart Data Intervention Performance Trial Survival Adults Quality Percutaneous Blood

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