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Circulation. Cardiovascular quality and outcomes
Research Hotspot & Journal Scope - Inhibitors

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Circulation. Cardiovascular quality and outcomes - DOI: 10.1161/CIRCOUTCOMES.118.005404

Effect of Access to Prescribed PCSK9 Inhibitors on Cardiovascular Outcomes

Kelly D Myers · Niloofar Farboodi · Mkaya Mwamburi · William Howard · David Staszak · Samuel Gidding · Seth J Baum · Katherine Wilemon · Daniel J Rader ·

Medicine
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Circulation. Cardiovascular quality and outcomes - DOI: 10.1161/CIRCOUTCOMES.119.005910

PCSK9 Inhibitors Prior Authorization.

Khurram Nasir · Suveen Angraal · Salim S Virani ·

Medicine
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suggest another route for intervention on FD, based on the exploitation of epigenetic manipulation of cell metabolism via HDAC8 inhibitors [1].

As a class, ‘BET’ inhibitors disrupt binding of bromodomain and extra-terminal motif (BET) proteins, BRD2, BRD3, BRD4 and BRDT, to acetylated histones preventing recruitment of RNA polymerase 2 to enhancers and promoters, especially super-enhancers, to inhibit gene transcription.

IntroductionGlutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione.

Therefore, the blockade of IL-1β production by using NLRP3 inflammasome inhibitors might be a novel potential strategy for the therapy and prevention of HMPV infection.

The results showed that the antiscalant efficiency for both groups of inhibitors increases with elongation of methylene chain, but the longest compounds have a sharp drop in inhibition efficiency.

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Research Hotspot

Circulation. Cardiovascular quality and outcomes

Research Hotspot

Journal Scope

Circulation. Cardiovascular quality and outcomes

Journal Scope

Patients Cardiovascular Acute Outcomes Myocardial Coronary Disease Infarction Clinical Randomized Heart Data Intervention Performance Trial Survival Adults Quality Percutaneous Blood Stroke Risk Health Systematic Therapy Long-Term Pressure Control Prediction Implantable Trials Mortality Older Association Hospital Cardiac Arrest Associated Patient Review Utilization Results Veterans Assessment Tracking United States Comparative Models Model Neural Networks Detection Failure Differences Practice Dog Ownership Meta-Analysis Integrating Controlled Trends Ischemic Standard Thirty-Day Readmission Hospitalized Effect PCSK9 Inhibitors Evidence Fragility Index Out-of-Hospital Examining Impact Automated Rates Physician Chronic Total Analysis Versus Anticoagulation Deep Treatment Measures Research Atrial Fibrillation Learning

Research Scope

Circulation. Cardiovascular quality and outcomes

Research Scope

Patients Cardiovascular Acute Outcomes Myocardial Coronary Disease Infarction Clinical Randomized Heart Data Intervention Performance Trial Survival Adults Quality Percutaneous Blood

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