Circulation. Cardiovascular quality and outcomes

Research Hotspot & Journal Scope - Anticoagulation

Background Regional anticoagulation with citrate during renal replacement therapy (RRT) reduces the risk of bleeding, extends dialyzer lifespan and is cost-effective.

The optimal anticoagulation regimen is still not certain as there are different fetal and maternal risks associated with anticoagulation.

A subset of high-risk pulmonary embolism (PE) patients requires advanced therapy beyond anticoagulation.

The formation of collateral vessels, bleeding, splenomegaly, hypersplenism during hospitalization or follow-up, and early anticoagulation and the occurrence of sinistral portal hypertension were evaluated.

CTA also demonstrated a well collateralized left subclavian vein and a decision was made to permanently stop anticoagulation, with the balance of risk for recurrent venous thrombosis without anticoagulation versus bleeding felt to be in favour of cessation.