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Circulation. Cardiovascular quality and outcomes
Research Hotspot & Journal Scope - Anticoagulation


Circulation. Cardiovascular quality and outcomes - DOI: 10.1161/CIRCOUTCOMES.119.006212
Net Clinical Benefit of Oral Anticoagulation Among Older Adults With Atrial Fibrillation.

Sachin J Shah · Daniel E Singer · Margaret C Fang · Kristi Reynolds · Alan S Go · Mark H Eckman ·

Medicine
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Circulation. Cardiovascular quality and outcomes - DOI: 10.1161/CIRCOUTCOMES.119.005659
Cost-Effectiveness of Pharmacomechanical Catheter-Directed Thrombolysis Versus Standard Anticoagulation in Patients With Proximal Deep Vein Thrombosis: Results From the ATTRACT Trial.

Elizabeth A Magnuson · Khaja Chinnakondepalli · Katherine Vilain · Clive Kearon · Jim A Julian · Susan R Kahn · Samuel Z Goldhaber · Michael R Jaff · Andrei L Kindzelski · Kevin Herman · Paul S Brady · Karun Sharma · Carl M Black · Suresh Vedantham · David J Cohen ·

Medicine
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BACKGROUND The difference in coagulation state during the periprocedural period of atrial fibrillation (AF) ablation among patients with uninterrupted anticoagulation has not been fully elucidated.

Prospective comparison of periprocedural coagulation markers among uninterrupted anticoagulants for atrial fibrillation ablation. [10.1016/j.hrthm.2019.10.015]


Given that heparin may be used during HPC‐A collections, these cases emphasize the importance of prompt consideration of HIT in patients that develop thrombocytopenia and thrombosis following HPC‐A collection with heparin anticoagulation.

Heparin‐induced thrombocytopenia associated with collection of hematopoietic progenitor cells by apheresis [10.1002/jca.21757]


The patient recovered fully after antibiotic therapy and a 3-month course of anticoagulation treatment.

Splenic infarction associated with transient anti-prothrombin antibodies is a rare manifestation of acute Mycoplasma pneumoniae infection. [10.1016/j.arcped.2019.10.001]


OBJECTIVE This review provides a concise, balanced overview of the current and future approaches for reversing the anticoagulation effects of DOACs, particularly factor Xa (FXa) inhibitors.

Current Strategies for the Management of Bleeding Associated with Direct Oral Anticoagulants and a Review of Investigational Reversal Agents. [10.1016/j.jemermed.2019.10.011]


Our findings provided useful information for risk stratification depending on TTR level and for future investigations on the quality of oral anticoagulation control in Brazilian anticoagulation clinics.

Non-genetic factors and polymorphisms in genes CYP2C9 and VKORC1: predictive algorithms for TTR in Brazilian patients on warfarin [10.1007/s00228-019-02772-4]



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