PLoS ONE

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PLOS ONE welcomes original research submissions from the natural sciences, medical research, engineering, as well as the related social sciences and humanities, including: -Primary research that contributes to the base of scientific knowledge, including interdisciplinary, replication studies, and negative or null results. -Systematic reviews whose methods ensure the comprehensive and unbiased sampling of existing literature. -Submissions describing methods, software, databases, or other tools that meet the journal’s criteria for utility, validation and availability. -Qualitative research that adheres to appropriate study design and reporting guidelines. PLOS One (stylized PLOS ONE, and formerly PLoS ONE) is a peer-reviewed open access scientific journal published by the Public Library of Science (PLOS) since 2006. The journal covers primary research from any discipline within science and medicine. The Public Library of Science began in 2000 with an online petition initiative by Nobel Prize winner Harold Varmus, formerly director of the National Institutes of Health and at that time director of Memorial Sloan?“Kettering Cancer Center; Patrick O. Brown, a biochemist at Stanford University; and Michael Eisen, a computational biologist at the University of California, Berkeley, and the Lawrence Berkeley National Laboratory.