Whole Cell Inactivated(全细胞灭活)研究综述
Whole Cell Inactivated 全细胞灭活 - Several vaccines, including mRNA, adenoviral-vectored, protein subunit and whole-cell inactivated virus vaccines, have now reported efficacy in phase III trials and have received emergency approval in many countries. [1] A genetically- modified, whole-cell inactivated Schizosaccharomyces pombe that produces a novel form of selenium called selenoneine was used as a prebiotic supplement in this study. [2] Whole-cell inactivated vaccines remain the only licensed vaccines used to control human and animal leptospirosis worldwide. [3] X-ray irradiation has been used to prepare whole-cell inactivated vaccines against P. [4] In general, subunit vaccines are safer but may be less immunogenic than whole cell inactivated or live attenuated vaccines. [5]几种疫苗，包括 mRNA、腺病毒载体、蛋白质亚单位和全细胞灭活病毒疫苗，现已在 III 期试验中报告了疗效，并在许多国家获得了紧急批准。 [1] 在这项研究中，一种经过基因改造的全细胞灭活粟酒裂殖酵母可产生一种称为硒酮的新型硒，用作益生元补充剂。 [2] 全细胞灭活疫苗仍然是世界范围内用于控制人类和动物钩端螺旋体病的唯一获得许可的疫苗。 [3] X 射线辐照已被用于制备针对 P. P.的全细胞灭活疫苗。 [4] 一般来说，亚单位疫苗更安全，但免疫原性可能低于全细胞灭活疫苗或减毒活疫苗。 [5]