Vivo Mrs(我住夫人)研究综述
Vivo Mrs 我住夫人 - In vivo MRSI provided high spectral quality (median signal-to-noise ratios, >6. [1] Recommendations are provided regarding the various assumptions made when computing a basis set for in vivo MRS with respect to the number of spatial points simulated and the consideration of relaxation. [2] Results: The proposed method applied on both simulated and in-vivo MRSI signals showed good water suppression performance. [3] We compare ex vivo and in vivo methods for studying metabolism in the brain using NMR and highlight insights gained through using higher magnetic fields, the advent of dissolution dynamic nuclear polarization, and combining in vivo MRS and ex vivo NMR approaches. [4] Our new method is also validated by analyzing previously published in vivo MRSI spectra. [5] In in vivo MRSA biofilm-infected wounds, the CS/NO film-treated group showed faster biofilm dispersal, wound size reduction, epithelialization rates, and collagen deposition than the untreated and CS film-treated groups. [6] Finally, the facile and robust antibacterial system is successfully applied to in vivo MRSA-infected wound healing, providing a significant reference for the construction of advanced antibacterial biomaterials. [7] These consist of direct applications of the FPT to time signals encoded by in vivo MRS from tumorous tissues. [8] Synthesized wound dressing material is screened for their morphology, water absorption capacity; in vitro drug release patterns, in vitro antibacterial studies against gram +ve and a gram -ve bacteria, cell viability for 3T3-L1 cell lines as well as in vivo MRSA infected wound healing capability. [9] In vivo MRSA-induced abscess treatment studies showed faster healing when CS-MP-Ce6 was used as subcutaneous nano-localized energy sources with the assistance of external magnet to concentrate CS-MP-Ce6-bacteria conjugate. [10]体内 MRSI 提供了高光谱质量（中值信噪比，>6。 [1] 提供了关于在计算体内 MRS 的基组时所做的各种假设的建议，这些假设涉及模拟的空间点的数量和松弛的考虑。 [2] 结果：所提出的方法应用于模拟和体内 MRSI 信号均显示出良好的水抑制性能。 [3] 我们比较了使用 NMR 研究大脑代谢的体外和体内方法，并强调了通过使用更高的磁场、溶解动态核极化的出现以及结合体内 MRS 和体外 NMR 方法获得的见解。 [4] 我们的新方法也通过分析先前发表的体内 MRSI 光谱得到验证。 [5] 在体内 MRSA 生物膜感染的伤口中，与未处理和 CS 膜处理组相比，CS/NO 膜处理组显示出更快的生物膜分散、伤口尺寸减小、上皮化率和胶原沉积。 [6] 最后，该简便而强大的抗菌系统成功应用于体内MRSA感染的伤口愈合，为构建先进的抗菌生物材料提供了重要参考。 [7] 这些包括将 FPT 直接应用于由来自肿瘤组织的体内 MRS 编码的时间信号。 [8] 筛选合成的伤口敷料材料的形态、吸水能力；体外药物释放模式、针对 gram +ve 和 gram -ve 细菌的体外抗菌研究、3T3-L1 细胞系的细胞活力以及体内 MRSA 感染的伤口愈合能力。 [9] 体内 MRSA 诱导的脓肿治疗研究表明，当 CS-MP-Ce6 用作皮下纳米定位能源并借助外部磁体浓缩 CS-MP-Ce6-细菌共轭物时，愈合更快。 [10]