Suture Fusion(缝合融合)研究综述
Suture Fusion 缝合融合 - BACKGROUND Surgical repair for craniosynostosis varies depending on the infant's age, location of suture fusion, and approach (e. [1] Besides genetic factors, epigenetic factors like microRNAs and mechanical forces also play important roles in suture fusion. [2] On histology/electron microscopy, no changes in suture biology were evident for dipyridamole, whereas rhBMP-2 demonstrated early signs of suture fusion. [3] 05) at the head regions with abnormal development due to suture fusion. [4]背景 颅缝早闭的手术修复取决于婴儿的年龄、缝线融合的位置和方法（例如 [1] 除了遗传因素外，microRNAs和机械力等表观遗传因素也在缝合线融合中发挥重要作用。 [2] 在组织学/电子显微镜下，双嘧达莫的缝合生物学没有明显变化，而 rhBMP-2 显示缝合线融合的早期迹象。 [3] 05) 缝合线融合导致发育异常的头部区域。 [4]
Premature Suture Fusion 过早缝合融合
Data on premature suture fusion, age at first visit, age at surgery, skull thickness, and complications were collected. [1] Premature suture fusion, segmentation failure, cleft palate and neural tube defects such as spina bifida and anencephaly are discussed. [2] The latter could trigger upregulated calvarial osteogenesis leading to premature suture fusion, skull bone thickening, and craniotomized bone strip outgrowth observed in the present case. [3] In utero exposure to nicotine and citalopram (SSRI) increased the risk of premature suture fusion in a wild-type murine model. [4]收集有关过早缝合融合、首次就诊年龄、手术年龄、颅骨厚度和并发症的数据。 [1] 讨论了过早的缝合融合、分割失败、腭裂和神经管缺陷，如脊柱裂和无脑畸形。 [2] 后者可能引发上调的颅骨成骨，导致在本病例中观察到的过早缝合融合、颅骨增厚和开颅骨条生长。 [3] 在野生型小鼠模型中，子宫内暴露于尼古丁和西酞普兰 (SSRI) 会增加缝合线过早融合的风险。 [4]
Cranial Suture Fusion 颅缝融合术
Background Sagittal craniosynostosis (SCS), the most common type of premature perinatal cranial suture fusion, results in abnormal head shape that requires extensive surgery to correct. [1] Sagittal craniosynostosis (SCS), the most common type of premature perinatal cranial suture fusion, results in abnormal head shape that requires extensive surgery to correct. [2] Patients who underwent their first EES of the skull base before age 7 (prior to cranial suture fusion) and had a complete set of pre- and postoperative imaging studies (CT or MRI) with at least 1 year of follow-up were included. [3] Background: Certain intrauterine risk factors are known to increase the risk of premature cranial suture fusion and may cause complications during birth. [4]背景矢状性颅缝早闭 (SCS) 是围产期过早颅缝融合的最常见类型，导致头部形状异常，需要大量手术来纠正。 [1] 矢状性颅缝早闭 (SCS) 是围产期过早颅缝融合最常见的类型，会导致头部形状异常，需要进行大量手术才能矫正。 [2] 包括在 7 岁之前（颅缝融合之前）接受第一次颅底 EES 并进行了至少 1 年随访的完整的术前和术后影像学研究（CT 或 MRI）的患者。 [3] 背景：已知某些宫内危险因素会增加颅骨缝合线过早融合的风险，并可能导致分娩并发症。 [4]
Sagittal Suture Fusion 矢状缝融合
RESULTS The most common forms of craniosynostosis associated with metabolic bone disorder were isolated sagittal suture fusion with or without scaphocephaly, and sagittal suture fusion associated with coronal suture fusion (oxycephaly) or also with lambdoid suture fusion (pansynostosis). [1] This study highlights that sagittal suture fusion and Chiari type I malformation are frequent complications of XLHR. [2]结果 与代谢性骨疾病相关的最常见形式的颅缝早闭是孤立的矢状缝融合伴或不伴头颅畸形，以及与冠状缝融合（氧头畸形）或人字缝融合（全缝早闭）相关的矢状缝融合。 [1] 本研究强调矢状缝融合和 Chiari I 型畸形是 XLHR 的常见并发症。 [2]
suture fusion may 缝合融合可能
Evidence of right unilateral coronal brain laterality suggests that the area of suture fusion may contribute to the mechanism of dysfunction. [1] Evidence of R-ULC brain laterality suggest that the area of suture fusion may contribute to the mechanism of dysfunction. [2]右侧单侧冠状脑偏侧的证据表明缝合融合区域可能有助于功能障碍的机制。 [1] R-ULC 脑侧向性的证据表明缝合融合区域可能有助于功能障碍的机制。 [2]