Spect Ct Imaging(Spect Ct 成像)研究综述
Spect Ct Imaging Spect Ct 成像 - Conclusions Our data suggests that SPECT/CT imaging does not add significant value to planar images and should not be adopted in routine clinical practice. [1] Lumbar chordoma could be one of the differential diagnoses for lytic lesions of the vertebrae which show absent or minimal tracer uptake on bone scintigraphy and SPECT/CT imaging. [2] Conclusions This study demonstrates that LSF calculation using planar imaging can be significantly overestimated while calculation using SPECT/CT imaging and appropriate segmentation tools can be more accurate. [3] 5 could be a reasonable cutoff for determining HER2 positivity using SPECT/CT imaging. [4] The usefulness of bone SPECT/CT imaging with volume of interest analysis in early axial spondyloarthritis. [5] Patients and Methods: This prospective study included twenty-five patients (17 males and 8 females) with clinically diagnosed MOE, all of themunderwent both HRCT and 99mTc-MDP SPECT/CT imaging of the skull. [6] BACKGROUND The diagnostic accuracy of bone scintigraphy (BS) increases with SPECT/CT imaging. [7] Tc-99 SPECT/CT imaging was subsequently performed in this cohort and treatment was determined according to imaging results. [8] Hybrid planar-SPECT/CT imaging was used, including quantitative SPECT reconstruction, voxel-based absorbed-dose-rate calculation, semi-automatic image segmentation, and partial-volume correction. [9] In addition, the assessments of the aorta in the ApoE−/− mice at different stages were performed using in vivo SPECT/CT imaging, and the findings were compared by histology. [10] The aim of this study was to compare the biodistribution of p5R and bFGF in healthy mice as well as those with systemic inflammation-associated amyloidosis (AA), which contains HSPG, by using SPECT/CT imaging, tissue biodistribution measurements and micro-autoradiography. [11] The simplified fixed measurement method of radiopharmaceutical radioactivity can be used as an alternative method in cases when measuring the radioactivity in quantitative bone SPECT/CT imaging is missed. [12] Our aim was to introduce hexahistidine (His6) peptides into pertuzumab Fab to enable labeling with the [99mTc(CO)3(H2O)3]+ complex and study these radioimmunoconjugates for microSPECT/CT imaging of HER2-positive tumor xenografts in mice. [13] Data acquisition for dosimetry of normal organs and tumors was performed by whole-body and 3D SPECT/CT imaging at 4, 24, 48, and 96 hours after administering 177Lu-FAPI04. [14] In addition, higher accumulation, longer dwell time, and increased tumor-to-organ ratios were achieved by 131I-FAPI-04, which was clearly demonstrated by SPECT/CT imaging. [15] In this work we evaluate both the imaging and dosimetric characteristics of 67Cu, as well as producing the first report of SPECT/CT imaging using 67Cu. [16] Both subcutaneous and in situ BxPC-3 tumors could be clearly visualized by 99mTc-isoDGR nanoScan SPECT/CT imaging with a high ratio of tumor to background. [17] 111In-labeled poly(lactic-co-glycolic acid) with a primary amine endcap nanoparticles ([111In]In-PLGA-NH2 NPs) were previously used for cell labeling and in vivo tracking, using SPECT/CT imaging. [18] Biodistribution and SPECT/CT imaging studies confirmed the favorable effect of an albumin-binding entity to increase the tumor uptake and reduce kidney retention of folate radioconjugates. [19] 001), and SPECT/CT imaging revealed a larger number of uptake lesions than those noted in planar imaging for each patient (3. [20] SPECT/CT imaging studies showed obvious accumulation in tumor sites, suggesting that 99mTc-CN7DG is a promising candidate for tumor imaging. [21] While 68Ga PSMA is a generator-derived PET radiopharmaceutical, SPECT/CT imaging using technetium-99m-labeled PSMA is now available as a suitable alternative. [22] Also, an axial fused SPECT/CT imaging showed myocardial uptake, mostly evident in the left ventricular lateral wall. [23] ), and consequently, tomographic SPECT/CT imaging was performed, for up to 24 hours p. [24] Novel minigastrins (NMGs) as analogs of PP-F11N with one or two amide bonds substituted by 1,2,3-triazoles were synthesized, radiolabeled with 177Lu3+, and subjected to full evaluation in vitro (cell internalization, receptor affinity, stability in blood plasma) and in vivo (stability, biodistribution, SPECT/CT imaging). [25] Purpose: This study aims to investigate the feasibility of ITGA5-targeted SPECT/CT imaging of pancreatic cancer by targeting PSCs. [26] 6% respectively on SPECT/CT imaging. [27] ConclusionsThis study demonstrates that LSF calculation using planar imaging can be significantly overestimated while calculation using SPECT/CT imaging and appropriate segmentation tools can be more accurate. [28] We retrospectively analyzed 1600 low- to intermediate risk symptomatic patients referred for clinically indicated cardiac SPECT/CT imaging with a CAC score of zero. [29] Repeat SPECT/CT imaging is performed immediately following, and at 1, 3, 5, and 8 days after 186RNL infusion to obtain dosimetry and distribution. [30] The MRTDosimetry project was a European initiative to bring together expertise in metrology and nuclear medicine research, with one main goal of standardizing quantitative 177 Lu SPECT/CT imaging based on a calibration protocol developed and tested in a multicentre inter-comparison. [31] To overcome the limited depth penetration of fluorescent light, combining fluorescence with SPECT/CT imaging and/or gamma-ray tracing has been proposed. [32] The biodistribution study and SPECT/CT imaging were conducted on KM mice. [33] Conclusion: SPECT/CT imaging is a feasible technique to facilitate image interpretation in patients with GIB. [34] 0, and tumor-bearing mice were subjected to small-animal SPECT/CT imaging studies. [35] SPECT/CT imaging of a triple line phantom containing 111In in air and water was performed. [36] In vivo SPECT/CT imaging shows high accumulation in the inflamed joints of mice with RA after intravenous injection of HSP-PEG-NPs with 99mTc labeling (99mTc-HSP-PEG). [37] 99 years) with suspected ATTR referred for Tc-DPD imaging had planar and SPECT/CT imaging of the chest. [38] Importantly, in vivo phototherapy guided by SPECT/CT imaging alleviates plaque progression. [39] The value of VQ SPECT/CT imaging is also shown in this study, in detecting and differentiating the various types of perfusion abnormalities. [40] SPECT/CT imaging was performed at 24 h, and tumor volume was determined up to 100 days. [41] The aim of this study was to evaluate the performance of a novel semi-automated quantitative software to diagnose ATTR cardiac amyloidosis in patients with a clinical suspicion of cardiac amyloidosis who underwent 99m-Tc-PYP SPECT/CT imaging. [42] We also assess the ability of the inflammatory markers CRP and ESR to predict osteomyelitis diagnosis by 99mTc-WBC SPECT/CT imaging. [43] Biodistribution and SPECT/CT imaging studies were carried out with the respective tumor mouse models using 0. [44] The EV radiolabeling protocol using 99mTc-Duramycin may provide a fast and simple labeling approach for SPECT/CT imaging of EVs biodistribution. [45] The radiopeptides were further investigated in AR42J tumor-bearing nude mice using the method of dual-isotope (terbium-161/lutetium-177) SPECT/CT imaging to enable the visualization of their distribution profiles in the same animal. [46] Single-photon emitting agents used for identifying lung infection include 67Ga-citrate, 111In-oxine-leukocytes, 99mTc-HMPAO-leukocytes, preferably employing SPECT/CT imaging. [47] This study aimed to explore further the correlation between 99mTc-MIBI SPECT/CT imaging and SHPT to demonstrate the value of 99mTc-MIBI SPECT/CT in evaluating the degree of pathological hyperplasia of the parathyroid gland (PG). [48] SPECT/CT imaging and dosimetry calculations were performed for [99mTc]Tc-maSSS-PEG2-RM26. [49] SPECT/CT imaging showed that radiolabeled THP-1 cells accumulated at the Staphylococcus aureus infection site in mice. [50]结论 我们的数据表明，SPECT/CT 成像不会显着增加平面图像的价值，不应在常规临床实践中采用。 [1] 腰椎脊索瘤可能是椎骨溶解性病变的鉴别诊断之一，其在骨闪烁扫描和 SPECT/CT 成像中显示缺乏或极少的示踪剂摄取。 [2] 结论 本研究表明，使用平面成像的 LSF 计算可能被严重高估，而使用 SPECT/CT 成像和适当的分割工具的计算可以更准确。 [3] 5 可能是使用 SPECT/CT 成像确定 HER2 阳性的合理截止值。 [4] 骨 SPECT/CT 成像与感兴趣体积分析在早期中轴型脊柱关节炎中的有用性。 [5] 患者和方法：这项前瞻性研究包括25名临床诊断为MOE的患者（17名男性和8名女性），他们均接受了颅骨的HRCT和99mTc-MDP SPECT/CT成像。 [6] 背景 骨闪烁显像 (BS) 的诊断准确性随着 SPECT/CT 成像的增加而提高。 [7] 随后在该队列中进行了 Tc-99 SPECT/CT 成像，并根据成像结果确定治疗方案。 [8] 使用混合平面-SPECT/CT成像，包括定量SPECT重建、基于体素的吸收剂量率计算、半自动图像分割和部分体积校正。 [9] 此外，使用体内 SPECT/CT 成像对不同阶段的 ApoE-/- 小鼠的主动脉进行了评估，并通过组织学比较了研究结果。 [10] 本研究的目的是通过使用 SPECT/CT 成像、组织生物分布测量和显微放射自显影，比较 p5R 和 bFGF 在健康小鼠以及含有 HSPG 的全身炎症相关淀粉样变性 (AA) 小鼠中的生物分布。 [11] 放射性药物放射性的简化固定测量方法可以作为一种替代方法，用于在定量骨 SPECT/CT 成像中无法测量放射性的情况下。 [12] 我们的目标是将六组氨酸 (His6) 肽引入帕妥珠单抗 Fab，以使用 [99mTc(CO)3(H2O)3]+ 复合物进行标记，并研究这些放射免疫偶联物用于小鼠 HER2 阳性肿瘤异种移植物的 microSPECT/CT 成像。 [13] 在施用 177Lu-FAPI04 后 4、24、48 和 96 小时，通过全身和 3D SPECT/CT 成像进行正常器官和肿瘤剂量测定的数据采集。 [14] 此外，131I-FAPI-04 实现了更高的积累、更长的停留时间和更高的肿瘤与器官比率，SPECT/CT 成像清楚地证明了这一点。 [15] 在这项工作中，我们评估了 67Cu 的成像和剂量学特征，并首次报告了使用 67Cu 的 SPECT/CT 成像。 [16] 99mTc-isoDGR nanoScan SPECT/CT 成像可以清楚地显示皮下和原位 BxPC-3 肿瘤，肿瘤与背景的比例很高。 [17] 111In 标记的聚（乳酸-共-乙醇酸）与伯胺封端纳米粒子（[111In]In-PLGA-NH2 NPs）以前用于细胞标记和体内追踪，使用 SPECT/CT 成像。 [18] 生物分布和 SPECT/CT 成像研究证实了白蛋白结合实体对增加肿瘤摄取和减少叶酸放射性结合物的肾潴留的有利作用。 [19] 001），SPECT/CT 成像显示每个患者的摄取病灶数量多于平面成像（3. [20] SPECT/CT 成像研究显示在肿瘤部位有明显的积累，表明 99mTc-CN7DG 是一种很有前途的肿瘤成像候选物。 [21] 虽然 68Ga PSMA 是一种源自发生器的 PET 放射性药物，但使用锝 99m 标记的 PSMA 的 SPECT/CT 成像现在可作为合适的替代品。 [22] 此外，轴向融合 SPECT/CT 成像显示心肌摄取，主要在左心室侧壁明显。 [23] )，因此，断层 SPECT/CT 成像进行了长达 24 小时 p。 [24] 合成新的胃泌素 (NMG) 作为 PP-F11N 的类似物，其中一个或两个酰胺键被 1,2,3-三唑取代，用 177Lu3+ 放射性标记，并在体外进行全面评估（细胞内化、受体亲和力、血液稳定性血浆）和体内（稳定性、生物分布、SPECT/CT成像）。 [25] 目的：本研究旨在探讨通过靶向 PSCs 对胰腺癌进行 ITGA5 靶向 SPECT/CT 成像的可行性。 [26] SPECT/CT 成像分别为 6%。 [27] 结论本研究表明，使用平面成像的 LSF 计算可能会被严重高估，而使用 SPECT/CT 成像和适当的分割工具的计算可以更准确。 [28] 我们回顾性分析了 1600 名中低危症状患者，这些患者被转诊进行有临床指征的心脏 SPECT/CT 成像，且 CAC 评分为零。 [29] 在 186RNL 输注后 1、3、5 和 8 天立即进行重复 SPECT/CT 成像，以获得剂量测定和分布。 [30] MRTDosimetry 项目是一项欧洲倡议，旨在汇集计量学和核医学研究方面的专业知识，其主要目标是根据在多中心相互比较中开发和测试的校准协议标准化定量 177 Lu SPECT/CT 成像。 [31] 为了克服荧光的有限深度穿透，已提出将荧光与 SPECT/CT 成像和/或伽马射线追踪相结合。 [32] 对KM小鼠进行生物分布研究和SPECT/CT成像。 [33] 结论：SPECT/CT 成像是一种促进 GIB 患者图像解释的可行技术。 [34] 0，对荷瘤小鼠进行小动物 SPECT/CT 成像研究。 [35] 对空气和水中含有 111In 的三线体模进行 SPECT/CT 成像。 [36] 体内 SPECT/CT 成像显示，在静脉注射具有 99mTc 标记的 HSP-PEG-NPs (99mTc-HSP-PEG) 后，RA 小鼠的发炎关节中有大量蓄积。 [37] 99 岁）疑似 ATTR 转诊进行 Tc-DPD 成像，胸部平面和 SPECT/CT 成像。 [38] 重要的是，由 SPECT/CT 成像引导的体内光疗可以减轻斑块的进展。 [39] 本研究还显示了 VQ SPECT/CT 成像在检测和区分各种类型的灌注异常方面的价值。 [40] 在 24 小时进行 SPECT/CT 成像，并确定肿瘤体积长达 100 天。 [41] 本研究的目的是评估一种新型半自动定量软件在临床疑似心脏淀粉样变性患者接受 99m-Tc-PYP SPECT/CT 成像时诊断 ATTR 心脏淀粉样变性的性能。 [42] 我们还通过 99mTc-WBC SPECT/CT 成像评估炎症标志物 CRP 和 ESR 预测骨髓炎诊断的能力。 [43] 生物分布和 SPECT/CT 成像研究是使用 0 对各自的肿瘤小鼠模型进行的。 [44] 使用 99mTc-Duramycin 的 EV 放射性标记方案可为 EV 生物分布的 SPECT/CT 成像提供一种快速简单的标记方法。 [45] 使用双同位素（terbium-161/lutetium-177）SPECT/CT 成像方法在 AR42J 荷瘤裸鼠中进一步研究了放射性肽，以实现它们在同一动物中的分布曲线的可视化。 [46] 用于识别肺部感染的单光子发射剂包括 67Ga-柠檬酸盐、111In-oxine-白细胞、99mTc-HMPAO-白细胞，优选采用 SPECT/CT 成像。 [47] 本研究旨在进一步探讨99mTc-MIBI SPECT/CT成像与SHPT的相关性，以论证99mTc-MIBI SPECT/CT在评估甲状旁腺（PG）病理性增生程度中的价值。 [48] 对 [99mTc]Tc-maSSS-PEG2-RM26 进行了 SPECT/CT 成像和剂量学计算。 [49] SPECT/CT 成像显示放射性标记的 THP-1 细胞在小鼠的金黄色葡萄球菌感染部位聚集。 [50]