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Deciphering the allosteric binding mechanism of the human tropomyosin receptor kinase A (hTrkA) inhibitors.


Deciphering the Allosteric Binding Mechanism of the Human Tropomyosin Receptor Kinase A ( hTrkA) Inhibitors.

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Binding and structural analyses of potent inhibitors of the human Ca2+/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors


Structural and binding studies of human CAMKK2 kinase domain bound to small molecule ligands

Small Molecule Kinase sentence examples within small molecule kinase inhibitor



Deciphering the allosteric binding mechanism of the human tropomyosin receptor kinase A (hTrkA) inhibitors.


Novel Screening Method Identifies PI3Kα, mTOR, and IGF1R as Key Kinases Regulating Cardiomyocyte Survival


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An innovative kinome platform to accelerate small-molecule inhibitor discovery and optimization from hits to leads.



Structural insights of oxindole based kinase inhibitors as anticancer agents: Recent advances.



Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function



Small-Molecule Kinase Inhibitors for the Treatment of Nononcologic Diseases.



Oncogenic mechanism-based pharmaceutical validation of therapeutics targeting MET receptor tyrosine kinase



PROactively TACkling CDK4/6 therapy resistance



Phase II trial of surufatinib plus toripalimab for disease progression after first-line chemotherapy with platinum and fluoropyrimidine in advanced gastric or gastroesophageal junction adenocarcinoma.



Analysis of the metabolomic profile in serum of irradiated nonhuman primates treated with Ex-Rad, a radiation countermeasure



Vascular Impact of Cancer Therapies



Trends in kinase drug discovery: targets, indications and inhibitor design.



Alterations in the RTK/Ras/PI3K/AKT pathway serve as potential biomarkers for immunotherapy outcome of diffuse gliomas


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Small Molecule Kinase 小分子激酶


Small Molecule Kinase 小分子激酶
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