Significant Carotid(显着颈动脉)研究综述
Significant Carotid 显着颈动脉 - OBJECTIVES Endarterectomy of the carotid artery (CEA) is a preventive procedure aimed at decreasing the subsequent risk of fatal or disabling stroke in patients with significant carotid stenosis. [1] Material and methods We retrospectively evaluated 599 patients with significant carotid artery stenosis, who underwent 763 CAS procedures, and used the propensity score to match 226 pairs (452 patients) in the single- or double-vessel carotid disease. [2] Emergency computed tomography (CT) angiography showed normal anatomy of the cerebral arteries without significant carotid artery disease. [3] In a pilot cohort of ten patients with significant carotid artery stenosis, calcified vessel detection by mcMRI achieved 64. [4] We studied the changes in in vitro fibrin network formation in three groups of patients—with acute coronary syndrome (ACS), with significant carotid artery stenosis (SCAS), and with acute ischemic stroke (AIS), as well as a control group. [5] The carotid arteries were evaluated with ultrasonography and divided into three types of carotid artery profiles (normal carotid artery, thick CIMT, or significant carotid atherosclerosis). [6] A 56-year-old female patient with significant carotid stenoses with circumferential plaques, causing localized vascular narrowing, was inappropriately indicated for carotid artery stenting. [7] 81), no significant carotid/intracranial artery stenosis (OR 3. [8] There is accruing evidence that hemodynamic impairment related to the presence of a significant carotid lumen narrowing may predispose to the development of cerebral dysfunctions, including a reduction in cognitive abilities. [9] The patient was severely comorbid: he suffered from metabolic syndrome, chronic kidney failure, hemodynamically significant carotid atheromasia, anemia, and he had a dubious history of epilepsy. [10] OBJECTIVE The aim of this study is to compare and to test the performance of all available risk scoring systems (RSSs) designed to predict long-term survival rate in asymptomatic candidate patients for carotid endarterectomy (CEA) for significant carotid artery stenosis. [11] We investigated inflammatory gene expression in the subcutaneous and the perivascular (pericarotid) adipose tissue from patients with carotid stenosis (CS) undergoing endarterectomy and a control group of patients without significant carotid atherosclerosis undergoing thyroid surgery. [12] Critical carotid stenosis, systemic arterial pressure and collateral vascular resistance are primary determinants of cerebral ischemic risk in patients with significant carotid stenosis. [13] Forgoing surveillance imaging in patients with hemodynamically significant carotid stenosis should be a shared decision between provider and patient and does not obviate the need for medical therapies. [14] METHODS Prospective part of the study: a total of 31 patients with significant carotid stenosis scheduled for carotid endarterectomy in regional anesthesia were enrolled. [15] In this work, diffusion magnetic resonance imaging (dMRI) is used to provide insight into structural brain changes that occur because of significant carotid artery stenosis, as well as changes that occur in response to CEA. [16] Radiological and histological analysis further revealed extensive arteriosclerosis with (non-obliterating) coronary and significant carotid arteriosclerosis, healthy bone tissue without evidence of age-related osteopenia, evidence for diffuse idiopathic skeletal hyperostosis and mild osteoarthrosis of few joints. [17] Objectives: To determine the frequency of significant carotid artery disease on carotid angiography in patients presenting with left main stem coronary artery disease. [18] This case report describes a 54-year-old male patient with repeated, transient ischemic attacks due to ipsilateral, significant carotid stenosis registered by carotid duplex ultrasound. [19] As a result, severe coronary artery disease (CAD) requiring coronary artery bypass graft (CABG) frequently coexists with significant carotid stenosis that warrants revascularization. [20] However, isolated morphological changes without significant carotid stenosis is rarely symptomatic. [21] The EX group also had a larger yet non-significant carotid lumen diameter (EX; 2. [22] Hemodynamically insignificant carotid plaques (stenosis <50%) was detected in 56. [23] Conclusion FDG-PET visualizes the inflammatory part of carotid atherosclerosis enabling risk stratification to a certain degree, whereas NaF-PET seems to indicate long-term consequences of ongoing inflammation by demonstrating microcalcification allowing discrimination of atherosclerotic from normal arteries and suggesting clinically significant carotid atherosclerosis. [24] OBJECTIVE Management of significant carotid stenosis in those with symptomatic coronary disease remains controversial. [25] OBJECTIVE To determine the frequency, risk factors, and outcomes of significant carotid artery disease (CAD) in patients with ischemic stroke. [26] The objective is to conduct a systematic review with meta-analysis and trial sequential analysis as well as Grading of Recommendations Assessment, Development and Evaluation (GRADE) assessments comparing the benefits and harms of CEA with primary closure of the arterial wall versus CEA with patch angioplasty in patients with a symptomatic and significant carotid stenosis. [27] MethodsWe retrospectively analyzed 675 CEAs, which were performed on 613 patients with significant carotid stenosis between January 2007 and December 2014. [28] Background and Purpose- Novel double layer micromesh stents have recently been introduced for treatment of patients with significant carotid stenosis. [29] Introduction Carotid artery stenting (CAS) is an effective treatment for clinically significant carotid artery stenosis in selected patients. [30] Multivariate models were constructed for the prediction of atherosclerotic CAD, significant carotid stenosis, atheroma burden and WMD. [31] Conclusion: Routine duplex screening will identify significant carotid artery disease and will subsequently reduce the risk of perioperative stroke in ischaemic heart disease patients undergoing coronary artery bypass graft surgery. [32] RESULTS One hundred twenty eight patients (72%) were having ICA disease, while significant carotid artery stenosis (>70%) was seen in 11 patients (6. [33] METHODS A total of 47 consecutive patients with significant carotid artery stenosis were enrolled into this investigation and followed up to 5 years to explore vascular complications. [34] 001) and had more significant carotid artery stenosis (30. [35] It is unclear whether incidental carotid artery calcification (CAC) on radiographs has a defined relationship to clinically significant carotid artery stenosis, and therefore risk of stroke. [36] Magnetic resonance angiography (MRA), computed tomographic (CT) angiography, and color Doppler sonography failed to identify any arterial dissection or significant carotid and vertebral stenosis. [37] Transcranial color-coded duplex was done to assess cerebral hemodynamics and collaterals to differentiate between extracranial significant carotid stenosis alone versus combined extra- and intracranial significant carotid stenosis. [38] BACKGROUND This meta-analysis aimed to evaluate randomized trials (RTs) that compare outcomes among asymptomatic patients with significant carotid stenosis undergoing carotid endarterectomy (CEA) versus carotid stenting (CAS) or best medical treatment (BMT). [39] Progression of WMHs in asymptomatic patients with non-hemodynamically significant carotid plaque could represent a putative marker of plaque vulnerability. [40] Objectives Carotid endarterectomy (CEA) is efficient in preventing stroke for patients with significant carotid stenosis, but results in mild cognitive dysfunction. [41] In this brief review, we analyze the incidence of significant carotid stenosis in patients undergoing CABG, association of untreated asymptomatic carotid stenosis on postoperative stroke, effects of carotid endarterectomy (CEA) on postoperative incidence of stroke, determination of surgical options and technical variations for CEA, scanning methods for identifying the vulnerable carotid plaque and revealing risk factors and predictors associated with stroke after CABG. [42] We report a patient with a transient ischemic attack and a right significant carotid artery stenosis presumably due to a compression of an elongated ICA by the hyoid bone. [43] Objective We estimated the cost-effectiveness of novel imaging tests to select patients for carotid endarterectomy (CEA) in patients with significant carotid stenosis using a computer model and explored the minimum prognostic performance that a new confirmatory test must have in order to be cost-effective versus the guideline-based strategy. [44]目标 颈动脉内膜切除术 (CEA) 是一种预防性手术，旨在降低严重颈动脉狭窄患者随后发生致命或致残性卒中的风险。 [1] 材料和方法 我们回顾性评估了 599 例颈动脉明显狭窄患者，这些患者接受了 763 次 CAS 手术，并使用倾向评分匹配单支或双支颈动脉疾病的 226 对（452 名患者）。 [2] 紧急计算机断层扫描 (CT) 血管造影显示脑动脉解剖正常，没有明显的颈动脉疾病。 [3] 在一个由 10 名患有明显颈动脉狭窄的患者组成的试点队列中，通过 mcMRI 检测到的钙化血管达到了 64 人。 [4] 我们研究了三组患者体外纤维蛋白网络形成的变化——急性冠状动脉综合征 (ACS)、颈动脉明显狭窄 (SCAS)、急性缺血性卒中 (AIS) 以及对照组。 [5] 用超声检查评估颈动脉，并将颈动脉分为三种类型（正常颈动脉、厚 CIMT 或显着颈动脉粥样硬化）。 [6] 一名 56 岁女性患者，颈动脉明显狭窄，周围有斑块，导致局部血管狭窄，不适用于颈动脉支架置入术。 [7] 81），没有明显的颈动脉/颅内动脉狭窄（OR 3. [8] 越来越多的证据表明，与颈动脉管腔显着狭窄相关的血流动力学障碍可能导致脑功能障碍的发生，包括认知能力下降。 [9] 患者有严重的合并症：他患有代谢综合征、慢性肾功能衰竭、血流动力学显着的颈动脉粥样硬化、贫血，并且他有可疑的癫痫病史。 [10] 客观的 本研究的目的是比较和测试所有可用的风险评分系统 (RSS) 的性能，这些系统旨在预测因严重颈动脉狭窄而行颈动脉内膜切除术 (CEA) 的无症状候选患者的长期生存率。 [11] 我们研究了接受内膜切除术的颈动脉狭窄 (CS) 患者和接受甲状腺手术的无明显颈动脉粥样硬化患者的皮下和血管周围 (颈动脉周围) 脂肪组织中的炎症基因表达。 [12] 严重颈动脉狭窄、全身动脉压和侧支血管阻力是严重颈动脉狭窄患者脑缺血风险的主要决定因素。 [13] 对血流动力学显着的颈动脉狭窄患者放弃监测成像应该是提供者和患者之间的共同决定，并且不排除对药物治疗的需要。 [14] 方法 研究的前瞻性部分：共招募了 31 名计划在区域麻醉下进行颈动脉内膜切除术的严重颈动脉狭窄患者。 [15] 在这项工作中，扩散磁共振成像 (dMRI) 用于深入了解由于颈动脉显着狭窄而发生的结构性大脑变化，以及响应 CEA 而发生的变化。 [16] 放射学和组织学分析进一步揭示了广泛的动脉硬化（非闭塞性）冠状动脉和明显的颈动脉硬化，健康的骨组织没有与年龄相关的骨质减少的证据，弥漫性特发性骨骼肥大和少数关节轻度骨关节病的证据。 [17] 目的：确定左主干冠状动脉疾病患者在颈动脉造影中出现明显颈动脉疾病的频率。 [18] 本病例报告描述了一名 54 岁男性患者，其反复、 同侧颈动脉明显狭窄导致的短暂性脑缺血发作 颈动脉双功能超声记录。 [19] nan [20] nan [21] nan [22] nan [23] nan [24] nan [25] nan [26] nan [27] nan [28] nan [29] nan [30] nan [31] nan [32] nan [33] nan [34] nan [35] nan [36] nan [37] nan [38] nan [39] nan [40] nan [41] nan [42] nan [43] nan [44]
Without Significant Carotid
Emergency computed tomography (CT) angiography showed normal anatomy of the cerebral arteries without significant carotid artery disease. [1] We investigated inflammatory gene expression in the subcutaneous and the perivascular (pericarotid) adipose tissue from patients with carotid stenosis (CS) undergoing endarterectomy and a control group of patients without significant carotid atherosclerosis undergoing thyroid surgery. [2] However, isolated morphological changes without significant carotid stenosis is rarely symptomatic. [3]紧急计算机断层扫描 (CT) 血管造影显示脑动脉解剖正常，没有明显的颈动脉疾病。 [1] 我们研究了接受内膜切除术的颈动脉狭窄 (CS) 患者和接受甲状腺手术的无明显颈动脉粥样硬化患者的皮下和血管周围 (颈动脉周围) 脂肪组织中的炎症基因表达。 [2] nan [3]
Clinically Significant Carotid
Conclusion FDG-PET visualizes the inflammatory part of carotid atherosclerosis enabling risk stratification to a certain degree, whereas NaF-PET seems to indicate long-term consequences of ongoing inflammation by demonstrating microcalcification allowing discrimination of atherosclerotic from normal arteries and suggesting clinically significant carotid atherosclerosis. [1] Introduction Carotid artery stenting (CAS) is an effective treatment for clinically significant carotid artery stenosis in selected patients. [2] It is unclear whether incidental carotid artery calcification (CAC) on radiographs has a defined relationship to clinically significant carotid artery stenosis, and therefore risk of stroke. [3]Hemodynamically Significant Carotid
The patient was severely comorbid: he suffered from metabolic syndrome, chronic kidney failure, hemodynamically significant carotid atheromasia, anemia, and he had a dubious history of epilepsy. [1] Forgoing surveillance imaging in patients with hemodynamically significant carotid stenosis should be a shared decision between provider and patient and does not obviate the need for medical therapies. [2] Progression of WMHs in asymptomatic patients with non-hemodynamically significant carotid plaque could represent a putative marker of plaque vulnerability. [3]患者有严重的合并症：他患有代谢综合征、慢性肾功能衰竭、血流动力学显着的颈动脉粥样硬化、贫血，并且他有可疑的癫痫病史。 [1] 对血流动力学显着的颈动脉狭窄患者放弃监测成像应该是提供者和患者之间的共同决定，并且不排除对药物治疗的需要。 [2] nan [3]
significant carotid stenosi
OBJECTIVES Endarterectomy of the carotid artery (CEA) is a preventive procedure aimed at decreasing the subsequent risk of fatal or disabling stroke in patients with significant carotid stenosis. [1] Critical carotid stenosis, systemic arterial pressure and collateral vascular resistance are primary determinants of cerebral ischemic risk in patients with significant carotid stenosis. [2] Forgoing surveillance imaging in patients with hemodynamically significant carotid stenosis should be a shared decision between provider and patient and does not obviate the need for medical therapies. [3] METHODS Prospective part of the study: a total of 31 patients with significant carotid stenosis scheduled for carotid endarterectomy in regional anesthesia were enrolled. [4] This case report describes a 54-year-old male patient with repeated, transient ischemic attacks due to ipsilateral, significant carotid stenosis registered by carotid duplex ultrasound. [5] As a result, severe coronary artery disease (CAD) requiring coronary artery bypass graft (CABG) frequently coexists with significant carotid stenosis that warrants revascularization. [6] However, isolated morphological changes without significant carotid stenosis is rarely symptomatic. [7] OBJECTIVE Management of significant carotid stenosis in those with symptomatic coronary disease remains controversial. [8] The objective is to conduct a systematic review with meta-analysis and trial sequential analysis as well as Grading of Recommendations Assessment, Development and Evaluation (GRADE) assessments comparing the benefits and harms of CEA with primary closure of the arterial wall versus CEA with patch angioplasty in patients with a symptomatic and significant carotid stenosis. [9] MethodsWe retrospectively analyzed 675 CEAs, which were performed on 613 patients with significant carotid stenosis between January 2007 and December 2014. [10] Background and Purpose- Novel double layer micromesh stents have recently been introduced for treatment of patients with significant carotid stenosis. [11] Multivariate models were constructed for the prediction of atherosclerotic CAD, significant carotid stenosis, atheroma burden and WMD. [12] Transcranial color-coded duplex was done to assess cerebral hemodynamics and collaterals to differentiate between extracranial significant carotid stenosis alone versus combined extra- and intracranial significant carotid stenosis. [13] BACKGROUND This meta-analysis aimed to evaluate randomized trials (RTs) that compare outcomes among asymptomatic patients with significant carotid stenosis undergoing carotid endarterectomy (CEA) versus carotid stenting (CAS) or best medical treatment (BMT). [14] Objectives Carotid endarterectomy (CEA) is efficient in preventing stroke for patients with significant carotid stenosis, but results in mild cognitive dysfunction. [15] In this brief review, we analyze the incidence of significant carotid stenosis in patients undergoing CABG, association of untreated asymptomatic carotid stenosis on postoperative stroke, effects of carotid endarterectomy (CEA) on postoperative incidence of stroke, determination of surgical options and technical variations for CEA, scanning methods for identifying the vulnerable carotid plaque and revealing risk factors and predictors associated with stroke after CABG. [16] Objective We estimated the cost-effectiveness of novel imaging tests to select patients for carotid endarterectomy (CEA) in patients with significant carotid stenosis using a computer model and explored the minimum prognostic performance that a new confirmatory test must have in order to be cost-effective versus the guideline-based strategy. [17]目标 颈动脉内膜切除术 (CEA) 是一种预防性手术，旨在降低严重颈动脉狭窄患者随后发生致命或致残性卒中的风险。 [1] 严重颈动脉狭窄、全身动脉压和侧支血管阻力是严重颈动脉狭窄患者脑缺血风险的主要决定因素。 [2] 对血流动力学显着的颈动脉狭窄患者放弃监测成像应该是提供者和患者之间的共同决定，并且不排除对药物治疗的需要。 [3] 方法 研究的前瞻性部分：共招募了 31 名计划在区域麻醉下进行颈动脉内膜切除术的严重颈动脉狭窄患者。 [4] 本病例报告描述了一名 54 岁男性患者，其反复、 同侧颈动脉明显狭窄导致的短暂性脑缺血发作 颈动脉双功能超声记录。 [5] nan [6] nan [7] nan [8] nan [9] nan [10] nan [11] nan [12] nan [13] nan [14] nan [15] nan [16] nan [17]
significant carotid artery
Material and methods We retrospectively evaluated 599 patients with significant carotid artery stenosis, who underwent 763 CAS procedures, and used the propensity score to match 226 pairs (452 patients) in the single- or double-vessel carotid disease. [1] Emergency computed tomography (CT) angiography showed normal anatomy of the cerebral arteries without significant carotid artery disease. [2] In a pilot cohort of ten patients with significant carotid artery stenosis, calcified vessel detection by mcMRI achieved 64. [3] We studied the changes in in vitro fibrin network formation in three groups of patients—with acute coronary syndrome (ACS), with significant carotid artery stenosis (SCAS), and with acute ischemic stroke (AIS), as well as a control group. [4] OBJECTIVE The aim of this study is to compare and to test the performance of all available risk scoring systems (RSSs) designed to predict long-term survival rate in asymptomatic candidate patients for carotid endarterectomy (CEA) for significant carotid artery stenosis. [5] In this work, diffusion magnetic resonance imaging (dMRI) is used to provide insight into structural brain changes that occur because of significant carotid artery stenosis, as well as changes that occur in response to CEA. [6] Objectives: To determine the frequency of significant carotid artery disease on carotid angiography in patients presenting with left main stem coronary artery disease. [7] OBJECTIVE To determine the frequency, risk factors, and outcomes of significant carotid artery disease (CAD) in patients with ischemic stroke. [8] Introduction Carotid artery stenting (CAS) is an effective treatment for clinically significant carotid artery stenosis in selected patients. [9] Conclusion: Routine duplex screening will identify significant carotid artery disease and will subsequently reduce the risk of perioperative stroke in ischaemic heart disease patients undergoing coronary artery bypass graft surgery. [10] RESULTS One hundred twenty eight patients (72%) were having ICA disease, while significant carotid artery stenosis (>70%) was seen in 11 patients (6. [11] METHODS A total of 47 consecutive patients with significant carotid artery stenosis were enrolled into this investigation and followed up to 5 years to explore vascular complications. [12] 001) and had more significant carotid artery stenosis (30. [13] It is unclear whether incidental carotid artery calcification (CAC) on radiographs has a defined relationship to clinically significant carotid artery stenosis, and therefore risk of stroke. [14] We report a patient with a transient ischemic attack and a right significant carotid artery stenosis presumably due to a compression of an elongated ICA by the hyoid bone. [15]材料和方法 我们回顾性评估了 599 例颈动脉明显狭窄患者，这些患者接受了 763 次 CAS 手术，并使用倾向评分匹配单支或双支颈动脉疾病的 226 对（452 名患者）。 [1] 紧急计算机断层扫描 (CT) 血管造影显示脑动脉解剖正常，没有明显的颈动脉疾病。 [2] 在一个由 10 名患有明显颈动脉狭窄的患者组成的试点队列中，通过 mcMRI 检测到的钙化血管达到了 64 人。 [3] 我们研究了三组患者体外纤维蛋白网络形成的变化——急性冠状动脉综合征 (ACS)、颈动脉明显狭窄 (SCAS)、急性缺血性卒中 (AIS) 以及对照组。 [4] 客观的 本研究的目的是比较和测试所有可用的风险评分系统 (RSS) 的性能，这些系统旨在预测因严重颈动脉狭窄而行颈动脉内膜切除术 (CEA) 的无症状候选患者的长期生存率。 [5] 在这项工作中，扩散磁共振成像 (dMRI) 用于深入了解由于颈动脉显着狭窄而发生的结构性大脑变化，以及响应 CEA 而发生的变化。 [6] 目的：确定左主干冠状动脉疾病患者在颈动脉造影中出现明显颈动脉疾病的频率。 [7] nan [8] nan [9] nan [10] nan [11] nan [12] nan [13] nan [14] nan [15]
significant carotid atherosclerosi
The carotid arteries were evaluated with ultrasonography and divided into three types of carotid artery profiles (normal carotid artery, thick CIMT, or significant carotid atherosclerosis). [1] We investigated inflammatory gene expression in the subcutaneous and the perivascular (pericarotid) adipose tissue from patients with carotid stenosis (CS) undergoing endarterectomy and a control group of patients without significant carotid atherosclerosis undergoing thyroid surgery. [2] Conclusion FDG-PET visualizes the inflammatory part of carotid atherosclerosis enabling risk stratification to a certain degree, whereas NaF-PET seems to indicate long-term consequences of ongoing inflammation by demonstrating microcalcification allowing discrimination of atherosclerotic from normal arteries and suggesting clinically significant carotid atherosclerosis. [3]用超声检查评估颈动脉，并将颈动脉分为三种类型（正常颈动脉、厚 CIMT 或显着颈动脉粥样硬化）。 [1] 我们研究了接受内膜切除术的颈动脉狭窄 (CS) 患者和接受甲状腺手术的无明显颈动脉粥样硬化患者的皮下和血管周围 (颈动脉周围) 脂肪组织中的炎症基因表达。 [2] nan [3]
significant carotid luman
There is accruing evidence that hemodynamic impairment related to the presence of a significant carotid lumen narrowing may predispose to the development of cerebral dysfunctions, including a reduction in cognitive abilities. [1] The EX group also had a larger yet non-significant carotid lumen diameter (EX; 2. [2]越来越多的证据表明，与颈动脉管腔显着狭窄相关的血流动力学障碍可能导致脑功能障碍的发生，包括认知能力下降。 [1] nan [2]