Shorter Treatment(较短的治疗)研究综述
Shorter Treatment 较短的治疗 - CONCLUSION ACE therapy could more effectively improve the gallbladder emptying with a shorter treatment course. [1] Moreover, immediate loading protocol seems to be a good option for the rehabilitation of fully edentulous patients, as it involves a shorter treatment time, which may lead to greater patient satisfaction. [2] Finally, this review highlights novel adjunctive therapeutic approaches against Mtb infection for better disease outcomes, shorter treatment duration, and improved treatment efficacy based on reciprocal interactions between current TB antibiotics and host immune cells. [3] Shorter treatment duration was associated with age groups of 7-12 and 13-15 years compared with 1-6 years (hazard ratio [HR]:1. [4] Shorter treatment duration may have been warranted with early initiation. [5] Purpose/Objective(s) The COVID19 pandemic required radiation oncologists (ROs) to consider shorter treatment courses to minimize patient and staff exposure and conserve healthcare resources. [6] Non-responders also had shorter treatment periods (4. [7] Since 2016, the World Health Organization has recommended shorter treatment regimens (STR). [8] Conclusions: The authors propose shorter, hypofractionated protocols with the option of selective concurrent chemotherapy in the management of head and neck cancer as well as the potential of shorter treatment options for esophageal and lung cancers and high grade gliomas. [9] In terms of biosafety and patient comfort, LED-based UVA1 phototherapy offers clear advantages over conventional treatment because of the use of a narrower and less harmful UVA1 spectrum, less heat generation and shorter treatment times at the same irradiation intensity. [10] Compared with the traditional way of afforestation, it has shorter treatment cycle and more convenient treatment method. [11] PBI presents an opportunity to improve quality of life during treatment with a significantly shorter treatment duration. [12] The shorter treatment schedule makes it an attractive option for treatment in primary head neck cancer especially in elderly, co-morbid and medically unfits patients. [13] Background: Applying mesenchymal stem cells (MSCs), together with the distraction osteogenesis (DO) process, displayed enhanced bone quality and shorter treatment periods. [14] The use of the drug Neurobion® is pathogenetically justified in the treatment of radiculopathy, provides earlier positive dynamics of subjective feelings of patients and objective indicators, improves the quality of life, leads to shorter treatment periods, reducing economic costs. [15] There were several significant intergroup differences in patient characteristics: r-tPA patients were more educated, had less history of stroke, lower systolic blood pressure, greater neurological impairment and shorter treatment times from symptom onset than UK patients. [16] In view of these findings, the authors suggest that shorter treatment duration should be assessed for safety and efficacy in future trials. [17] CONCLUSION Although shorter treatment regimens of radiation therapy were associated with lower rates of treatment noncompletion, disparities persisted in receipt of shorter regimens. [18] 05) were associated with shorter treatment course, elevated leukocytes (β = 0. [19] vaccine, new diagnostic tools, shorter treatment). [20] Shorter treatment times can be achieved through a combination of orthodontic and surgical or non-surgical techniques. [21] In Pakistan, the treatment of multidrug-resistant tuberculosis (MDR-TB) with a shorter treatment regimen (STR), that is, 4-6 months of amikacin, moxifloxacin (Mfx), ethionamide, clofazimine (Cfz), pyrazinamide (Z), ethambutol (E), and high-dose isoniazid, followed by 5 months of Mfx, Cfz, Z, and E, was initiated in 2018. [22] The trend is toward shorter treatment in view of lower rates of late and very late stent thrombosis with newer drug-eluting stents and the risk of bleeding with DAPT. [23] Shorter treatment times result in a better treatment experience for individual patients, reduces discomfort and the sides effects of inadvertent movements for them. [24] CONCLUSION Baseline MIP-1β/IL-12p40 ratio represents a non-invasive prognostic biomarker that would provide shorter treatment duration and minimizes the emergence of drug-resistant variants in HCV genotype 4-patients. [25] Infants with SVT and structurally normal cardiac anatomy, who remain recurrence free on a single agent, have no increased risk of recurrence with shorter treatment courses of 4–6 months, compared to traditional treatment duration of 6–12 months. [26] 05) were associated with shorter treatment course, elevated leukocytes (β=0. [27] Moreover, thermal relaxation times only affect the treatment outcomes for shorter treatment times of less than 30 s. [28] " Drug poisoning deaths were more common among patients who: 1) had recent positive drug test results; 2) had documented alprazolam use; 3) were younger; 4) had shorter treatment durations; 5) were female. [29] We used high auxin concentrations or longer treatments versus lower concentrations and shorter treatments of natural (IAA) and synthetic (NAA) auxins to distinguish between specific and nonspecific effects. [30] The antagonist protocol might be considered more advantageous because of the shorter treatment duration and lower doses of gonadotropin, and it allows more embryos to be transferred. [31] Conclusion The effectiveness of fiberoptic PT and blue light conventional PT were comparable in terms of bilirubin reduction rate and treatment duration, whereas fiberoptic phototherapy was more effective than white light conventional PT, with a significantly higher bilirubin reduction rate and shorter treatment duration. [32] Barriers for shorter treatment courses included concern for acute rheumatic fever development, parental pressure, fear of complications, and accustomed antibiotic duration. [33] Hypofractionation has benefits for both the patient and healthcare system, due to the shorter treatment duration. [34] Early treatment will result in a faster and shorter treatment course. [35] Our results showed that the SFA was able to achieve similar clinical outcomes to CSA but in a shorter treatment time. [36] Shorter treatment times and less root resorption were found in the TAD group. [37] The lower incidence of TRAE may partly attributed to that most pts (18/23) received lower initial dose (10mg) of anlotinib and the relatively shorter treatment duration. [38] ATI trial designs have evolved towards shorter treatment interruption phases and more frequent viral load monitoring aiming to reduce prolonged viremia risks. [39] EOPBM protocol was as effective as IOPBM in the management of OM in HSCT patients, with the advantage of shorter treatment sessions. [40] Introduction in Cameroon patients with multidrug/rifampicin resistant pulmonary tuberculosis (MDR/RR-PTB) are treated with a 9-11 month standardised shorter treatment regimen. [41] The modeled comparisons between 8- and 12-week treatment with G/P show that shorter treatment duration can lead to greater time and resource savings, both in terms of healthcare visits and downstream costs. [42] Compared with SEMS, ENPT is effective and safe in treating SLL after SG providing higher success rates, shorter treatment duration, and lower adverse events rates. [43] The technique decreases the number of breath holds per fraction, resulting in a shorter treatment session. [44] Moreover, GBT seemed to require shorter treatment time and to exhibit a more favorable patient perception than the conventional approach. [45] On multivariate analysis, achieving a non-CR response, immunotherapy given in advanced line, and shorter treatment duration were significantly associated with lesser progression-free survival. [46] Using comet assay it was observed that shorter treatment times (30–120 s) did not cause DNA damage. [47] The greater improvement in psychological and social characteristics in the SF approach compared to conventional orthognathic surgery may also be associated with a shorter treatment time. [48] The advantage of shorter treatment period with similar side effects makes the stair step protocol suitable for use in routine clinical practice. [49] To effectively counsel and treat patients with actinic keratoses, dermatologists must understand how newer therapeutic approaches with mechanisms of action that have more rapid onset of action, shorter treatment courses, and less intense local skin reaction (LSRs) may promote adherence and improve long-term outcomes. [50]结论 ACE治疗可以更有效地改善胆囊排空，疗程更短。 [1] 此外，即刻负重方案似乎是完全无牙颌患者康复的一个不错的选择，因为它涉及更短的治疗时间，这可能会导致更高的患者满意度。 [2] 最后，本综述强调了基于当前结核病抗生素和宿主免疫细胞之间相互作用的新型辅助治疗方法，以实现更好的疾病结果、更短的治疗时间和更高的治疗效果。 [3] 与 1-6 岁相比，7-12 岁和 13-15 岁年龄组的治疗持续时间较短（风险比 [HR]：1. [4] 早期开始治疗可能需要更短的治疗时间。 [5] 目的/目标 COVID19 大流行要求放射肿瘤学家 (RO) 考虑缩短治疗疗程，以尽量减少患者和工作人员的暴露并节省医疗资源。 [6] 无反应者的治疗期也较短（4. [7] 自 2016 年以来，世界卫生组织建议缩短治疗方案 (STR)。 [8] 结论：作者提出了较短的大分割方案，可选择选择性同步化疗来治疗头颈癌，以及食道癌、肺癌和高级别胶质瘤的较短治疗选择的潜力。 [9] 在生物安全性和患者舒适度方面，基于 LED 的 UVA1 光疗比传统治疗具有明显的优势，因为在相同照射强度下使用的 UVA1 光谱更窄，危害更小，产生的热量更少，治疗时间更短。 [10] 与传统的造林方式相比，处理周期更短，处理方式更方便。 [11] PBI 提供了一个改善治疗期间生活质量的机会，治疗时间显着缩短。 [12] 较短的治疗计划使其成为治疗原发性头颈癌的有吸引力的选择，尤其是在老年、合并症和医学上不适合的患者中。 [13] 背景：应用间充质干细胞 (MSCs) 以及牵张成骨 (DO) 过程，显示出增强的骨质量和更短的治疗时间。 [14] 使用药物 Neurobion® 在治疗神经根病方面具有病原学意义，可提供患者主观感受和客观指标的早期积极动态，提高生活质量，缩短治疗时间，降低经济成本。 [15] 患者特征有几个显着的组间差异：与英国患者相比，r-tPA 患者受教育程度更高、中风病史更少、收缩压更低、神经功能障碍更大以及从症状发作开始的治疗时间更短。 [16] 鉴于这些发现，作者建议在未来的试验中应评估较短的治疗持续时间的安全性和有效性。 [17] 结论 虽然较短的放射治疗方案与较低的治疗未完成率相关，但在接受较短方案方面仍存在差异。 [18] 05）与较短的疗程、升高的白细胞相关（β = 0. [19] 疫苗、新的诊断工具、更短的治疗时间）。 [20] 更短的治疗时间可以通过正畸和手术或非手术技术的结合来实现。 [21] 在巴基斯坦，耐多药结核病（MDR-TB）采用较短的治疗方案（STR），即4-6个月的阿米卡星、莫西沙星（Mfx）、乙硫异烟胺、氯法齐明（Cfz）、吡嗪酰胺（Z） 、乙胺丁醇（E）和大剂量异烟肼，随后是 5 个月的 Mfx、Cfz、Z 和 E，于 2018 年启动。 [22] 鉴于新型药物洗脱支架的晚期和极晚期支架血栓形成率较低以及 DAPT 的出血风险，趋势是缩短治疗时间。 [23] 更短的治疗时间可为个别患者带来更好的治疗体验，减少不适和无意运动的副作用。 [24] 结论 基线 MIP-1β/IL-12p40 比率代表一种非侵入性预后生物标志物，可提供更短的治疗持续时间并最大限度地减少 HCV 基因型 4 患者中耐药变异的出现。 [25] 与 6-12 个月的传统治疗持续时间相比，具有 SVT 且心脏解剖结构正常的婴儿在使用单一药物后仍无复发，在 4-6 个月的疗程中不会增加复发风险。 [26] 05）与较短的疗程、升高的白细胞相关（β=0. [27] 此外，热松弛时间仅影响小于 30 秒的较短治疗时间的治疗结果。 [28] " 药物中毒死亡在以下患者中更为常见：1) 近期药物检测结果呈阳性；2) 有记录使用阿普唑仑；3) 年龄较小；4) 治疗时间较短；5) 为女性。 [29] 我们使用高浓度或较长时间的处理与较低浓度和较短的天然 (IAA) 和合成 (NAA) 生长素处理来区分特异性和非特异性效应。 [30] 拮抗剂方案可能被认为更有利，因为治疗时间更短，促性腺激素剂量更低，并且可以转移更多的胚胎。 [31] 结论 光纤光疗与蓝光常规光疗在胆红素降低率和治疗时长上具有可比性，而光疗比白光光疗更有效，胆红素降低率明显更高，治疗时间更短。 [32] 较短疗程的障碍包括担心急性风湿热的发展、父母的压力、对并发症的恐惧和习惯的抗生素持续时间。 [33] 由于治疗时间较短，大分割对患者和医疗保健系统都有好处。 [34] 早期治疗将导致更快和更短的治疗过程。 [35] 我们的结果表明，SFA 能够达到与 CSA 相似的临床结果，但治疗时间更短。 [36] TAD 组的治疗时间更短，牙根吸收更少。 [37] TRAE发生率较低可能部分归因于大多数患者（18/23）接受较低的安罗替尼初始剂量（10mg）和较短的治疗时间。 [38] ATI 试验设计已向更短的治疗中断阶段和更频繁的病毒载量监测发展，旨在降低长期病毒血症的风险。 [39] EOPBM 方案在 HSCT 患者的 OM 管理中与 IOPBM 一样有效，具有治疗时间更短的优势。 [40] 在喀麦隆引入耐多药/利福平肺结核 (MDR/RR-PTB) 患者接受 9-11 个月的标准化较短治疗方案。 [41] 使用 G/P 进行 8 周和 12 周治疗之间的模型比较表明，更短的治疗时间可以节省更多的时间和资源，无论是就医疗保健访问和下游成本而言。 [42] 与 SEMS 相比，ENPT 治疗 SG 后 SLL 是有效且安全的，具有更高的成功率、更短的治疗时间和更低的不良事件发生率。 [43] 该技术减少了每部分的屏气次数，从而缩短了治疗时间。 [44] 此外，与传统方法相比，GBT 似乎需要更短的治疗时间并表现出更有利的患者感知。 [45] 在多变量分析中，实现非 CR 反应、在晚期给予的免疫治疗和较短的治疗持续时间与较低的无进展生存期显着相关。 [46] 使用彗星试验观察到较短的处理时间（30-120 秒）不会导致 DNA 损伤。 [47] 与传统的正颌手术相比，SF 方法在心理和社会特征方面的更大改善也可能与更短的治疗时间有关。 [48] 具有相似副作用的较短治疗期的优势使得阶梯式方案适用于常规临床实践。 [49] 为了有效地咨询和治疗光化性角化病患者，皮肤科医生必须了解具有起效更快、疗程更短和局部皮肤反应 (LSR) 强度更低的作用机制的新型治疗方法如何促进依从性并改善长期结果。 [50]
Significantly Shorter Treatment
PBI presents an opportunity to improve quality of life during treatment with a significantly shorter treatment duration. [1] 5% of patients, leading to a significantly shorter treatment duration. [2] Furthermore, hypofractionation allows for a significantly shorter treatment interval with a lower risk of progression during radiotherapy. [3] Conclusion : None of the drugs tested for treating neonatal abstinence syndrome resulted in a significantly shorter treatment length than the others. [4]PBI 提供了一个改善治疗期间生活质量的机会，治疗时间显着缩短。 [1] 5%的患者，导致治疗时间显着缩短。 [2] 此外，大分割可显着缩短治疗间隔，同时降低放射治疗期间的进展风险。 [3] nan [4]
Toward Shorter Treatment
The trend is toward shorter treatment in view of lower rates of late and very late stent thrombosis with newer drug-eluting stents and the risk of bleeding with DAPT. [1] ATI trial designs have evolved towards shorter treatment interruption phases and more frequent viral load monitoring aiming to reduce prolonged viremia risks. [2] The aim of this study was to assess clinician awareness of trials assessing the optimal duration of CRC adjuvant therapy, their attitudes towards shorter treatment and their self-reported practice. [3]鉴于新型药物洗脱支架的晚期和极晚期支架血栓形成率较低以及 DAPT 的出血风险，趋势是缩短治疗时间。 [1] ATI 试验设计已向更短的治疗中断阶段和更频繁的病毒载量监测发展，旨在降低长期病毒血症的风险。 [2] nan [3]
Relatively Shorter Treatment
The lower incidence of TRAE may partly attributed to that most pts (18/23) received lower initial dose (10mg) of anlotinib and the relatively shorter treatment duration. [1] PURPOSE/OBJECTIVE(S) External beam radiation therapy (EBRT) and brachytherapy boost should be completed in less than eight weeks, as better local tumor control and survival can be expected with relatively shorter treatment courses. [2]TRAE发生率较低可能部分归因于大多数患者（18/23）接受较低的安罗替尼初始剂量（10mg）和较短的治疗时间。 [1] 目的/目标 外照射放射治疗 (EBRT) 和近距离放射治疗应在 8 周内完成，因为相对较短的治疗疗程可实现更好的局部肿瘤控制和生存。 [2]
Require Shorter Treatment
Moreover, GBT seemed to require shorter treatment time and to exhibit a more favorable patient perception than the conventional approach. [1] Compared to riboflavin, decoron requires shorter treatment time and spares UV light exposure. [2]此外，与传统方法相比，GBT 似乎需要更短的治疗时间并表现出更有利的患者感知。 [1] 与核黄素相比，decreon 需要更短的处理时间并避免紫外线照射。 [2]
Oral Shorter Treatment
In 2019 Georgia has piloted the modified fully oral shorter treatment regimen in a routine programmatic condition. [1] Newer all-oral shorter treatment regimens are now being recommended and implemented worldwide, in the hope all MDR-TB patients can be treated and the gap can be filled rapidly through the use of a more simplified, cheaper, less toxic regimen which is easier to take, complete and result in fewer side effects, defaults and higher treatment success rates. [2]2019 年，佐治亚州在常规方案条件下试行了改良的全口服短期治疗方案。 [1] 新的全口服短期治疗方案现在正在世界范围内被推荐和实施，希望所有耐多药结核病患者都能得到治疗，并通过使用更简单、更便宜、毒性更低、更容易治疗的方案来迅速填补空白。采取、完成并导致更少的副作用、默认值和更高的治疗成功率。 [2]