Scaffold Promoted(脚手架推广)研究综述
Scaffold Promoted 脚手架推广 - Conclusion The 3D-printed scaffold promoted osteogenic differentiation of hADMSCs by upregulating hsa_circ_0019142. [1] The PFC/PCL-BA fibrous scaffold promoted the osteogenic differentiation of bone mesenchymal stem cells and stimulated the RAW264. [2] The GO-modified (2 mg/mL) composite scaffold promoted cell adhesion, cell proliferation, and chondrogenic differentiation in vitro. [3] Moreover, the incorporation of Fe2O3 to Ca-SAPO-34/CS scaffold promoted the proliferation of hDPSCs and osteogenic differentiation. [4] Micro-computed tomography and histological analysis results showed that the ECM in the scaffold promoted actual bone regeneration after in vivo implantation to a mouse calvarial defect model. [5] In vitro cellular experiments indicated that the MSCs-sEV-loaded composite scaffold promoted the adhesion and spreading of preosteoblast and endothelial cells, as well as enhanced osteogenic differentiation and angiogenic activity. [6] In-vitro studies proved that the scaffold promoted cellular proliferation. [7] Our study revealed that Collagen I scaffold promoted CSC properties and increased G1 population of FaDu cells in 3D cultures, accompanied by maturation of integrin β1 and enhanced activated TGF-β1 concentration. [8] The EV-functionalized scaffold promoted osteogenic differentiation (measured by increased ALP activity) and mineralization of the matrix. [9] In vivo, hesperidin combined with a suboptimal dose of bone morphogenetic protein 2 (BMP2) (dose unable to promote healing of a rat mandible critical-sized bone defect) in a collagenous scaffold promoted a well-controlled (not ectopic) pattern of bone formation as compared to a large dose of BMP2 (previously defined as optimal in healing the critical-sized defect, although of ectopic nature). [10] The bioglass-containing hybrid scaffold promoted osteogenic differentiation and calcium mineralization. [11] This scaffold promoted MSCs and EPCs early cell adhesion through up-regulating the expression of integrin α5β1 and integrin αvβ3 respectively, thus accelerated the following cell spreading, proliferation, and differentiation. [12] Moreover, a lot of pores produced by the degradation of the scaffold promoted the exposure of HAP from the matrix, which not only activated the deposition of bone like apatite on scaffold but also accelerated apatite growth. [13] Application of RA scaffold promoted an oriented arrangement of targeting ligands and reduced the shielding effect of corona proteins. [14] The MS/CS/B scaffold promoted the growth of new blood vessels and bone regeneration within 4 weeks of implantation in rabbits with induced critical-sized femoral defects. [15] This functional scaffold promoted the directional growth and remyelination of regenerating axons. [16] Furthermore, in vivo assays indicated that the scaffold promoted bone generation, with a new bone area fraction of 71. [17] In vivo anti-tumor effects in nude mice indicated that the HA/PDA/CMCS composite scaffold promoted cell apoptosis/necrosis by the direct photothermal effect. [18] scaffold promoted elongated cells spreading along its fibers’ axis, and a gradual linear cell growth, while the Ulva sp. [19]结论 3D打印支架通过上调hsa_circ_0019142促进hADMSCs的成骨分化。 [1] PFC/PCL-BA纤维支架促进骨间充质干细胞的成骨分化并刺激RAW264。 [2] GO 修饰 (2 mg/mL) 复合支架在体外促进细胞粘附、细胞增殖和软骨分化。 [3] 此外，将 Fe2O3 掺入 Ca-SAPO-34/CS 支架可促进 hDPSCs 的增殖和成骨分化。 [4] 微型计算机断层扫描和组织学分析结果表明，支架中的 ECM 在体内植入小鼠颅骨缺损模型后促进了实际的骨再生。 [5] 体外细胞实验表明，负载 MSCs-sEV 的复合支架促进了前成骨细胞和内皮细胞的粘附和扩散，并增强了成骨分化和血管生成活性。 [6] 体外研究证明，支架促进细胞增殖。 [7] 我们的研究表明，胶原蛋白 I 支架可促进 CSC 特性并增加 3D 培养物中的 G1 期 FaDu 细胞群，伴随着整合素 β1 的成熟和增强的活化 TGF-β1 浓度。 [8] EV 功能化支架促进成骨分化（通过增加的 ALP 活性来衡量）和基质的矿化。 [9] 在体内，橙皮苷与次优剂量的骨形态发生蛋白 2 (BMP2)（无法促进大鼠下颌骨临界大小骨缺损愈合的剂量）在胶原支架中促进了良好控制（非异位）的骨形成模式与大剂量的 BMP2 相比（以前定义为修复临界大小缺陷的最佳方法，尽管具有异位性质）。 [10] 含生物玻璃的混合支架促进成骨分化和钙矿化。 [11] 该支架通过分别上调整合素α5β1和整合素αvβ3的表达促进MSCs和EPCs早期细胞粘附，从而加速后续细胞的扩散、增殖和分化。 [12] 此外，支架降解产生的大量孔隙促进了HAP从基质中的暴露，不仅激活了骨样磷灰石在支架上的沉积，而且加速了磷灰石的生长。 [13] RA支架的应用促进了靶向配体的定向排列，降低了冠状蛋白的屏蔽作用。 [14] MS/CS/B 支架在兔体内植入后 4 周内促进了新血管的生长和骨再生，并诱发了严重的股骨缺损。 [15] 这种功能性支架促进再生轴突的定向生长和髓鞘再生。 [16] 此外，体内试验表明，支架促进骨生成，新骨面积分数为 71。 [17] 裸鼠体内抗肿瘤作用表明HA/PDA/CMCS复合支架通过直接光热效应促进细胞凋亡/坏死。 [18] 支架促进细长细胞沿其纤维轴扩散，并逐渐线性细胞生长，而石莼 sp。 [19]
Composite Scaffold Promoted
The GO-modified (2 mg/mL) composite scaffold promoted cell adhesion, cell proliferation, and chondrogenic differentiation in vitro. [1] In vitro cellular experiments indicated that the MSCs-sEV-loaded composite scaffold promoted the adhesion and spreading of preosteoblast and endothelial cells, as well as enhanced osteogenic differentiation and angiogenic activity. [2] In vivo anti-tumor effects in nude mice indicated that the HA/PDA/CMCS composite scaffold promoted cell apoptosis/necrosis by the direct photothermal effect. [3]GO 修饰 (2 mg/mL) 复合支架在体外促进细胞粘附、细胞增殖和软骨分化。 [1] 体外细胞实验表明，负载 MSCs-sEV 的复合支架促进了前成骨细胞和内皮细胞的粘附和扩散，并增强了成骨分化和血管生成活性。 [2] 裸鼠体内抗肿瘤作用表明HA/PDA/CMCS复合支架通过直接光热效应促进细胞凋亡/坏死。 [3]
scaffold promoted osteogenic
Conclusion The 3D-printed scaffold promoted osteogenic differentiation of hADMSCs by upregulating hsa_circ_0019142. [1] The EV-functionalized scaffold promoted osteogenic differentiation (measured by increased ALP activity) and mineralization of the matrix. [2] The bioglass-containing hybrid scaffold promoted osteogenic differentiation and calcium mineralization. [3]结论 3D打印支架通过上调hsa_circ_0019142促进hADMSCs的成骨分化。 [1] EV 功能化支架促进成骨分化（通过增加的 ALP 活性来衡量）和基质的矿化。 [2] 含生物玻璃的混合支架促进成骨分化和钙矿化。 [3]
scaffold promoted cell
The GO-modified (2 mg/mL) composite scaffold promoted cell adhesion, cell proliferation, and chondrogenic differentiation in vitro. [1] In vivo anti-tumor effects in nude mice indicated that the HA/PDA/CMCS composite scaffold promoted cell apoptosis/necrosis by the direct photothermal effect. [2]GO 修饰 (2 mg/mL) 复合支架在体外促进细胞粘附、细胞增殖和软骨分化。 [1] 裸鼠体内抗肿瘤作用表明HA/PDA/CMCS复合支架通过直接光热效应促进细胞凋亡/坏死。 [2]