Review Evolving(审查不断发展)研究综述
Review Evolving 审查不断发展 - Here, we review evolving clinical definitions of severe obstructive lung disease and evaluate how these have influenced trial design by summarising eligibility criteria and primary outcomes of phase III randomised controlled trials of biologic therapies. [1] We review evolving evidence on the role of atherosclerosis in stent restenosis and thrombosis, differentiating between de novo in-stent atherosclerosis development (i. [2] We describe the use of ex vivo T cell-depleted grafts as a model for the targeted graft and review evolving knowledge and approaches for further refinement of allografts to improve patient outcomes. [3]在这里，我们回顾了严重阻塞性肺病不断演变的临床定义，并通过总结生物疗法 III 期随机对照试验的资格标准和主要结果来评估这些定义如何影响试验设计。 [1] 我们回顾了关于动脉粥样硬化在支架再狭窄和血栓形成中作用的不断发展的证据，区分从头支架内动脉粥样硬化发展（即。 [2] 我们描述了使用离体 T 细胞耗尽的移植物作为靶向移植物的模型，并回顾了不断发展的知识和方法，以进一步完善同种异体移植物以改善患者的预后。 [3]