Regeneration Mode(再生模式)研究综述
Regeneration Mode 再生模式 - This paper presents the result of the analysis of the data gathered from 20 Role Models (RM) case studies regarding their successful heritage-led rural regeneration models. [1] In the present study, we found miR‐20a expression is decreased remarkably in three rodent liver regeneration models using miRNA PCR array and Venn diagram analysis. [2] This study accordingly proposes an extended theory of planned behavior model that uses goodness of regeneration mode (GRM) as a moderating construct and considers environmental concern (EC) and perceived value (PV) to determine the factors that affect public acceptance behavioral intention (BI). [3] This paper presents the construction of bone degradation and regeneration model and OCT imaging in vivo based on zebrafish. [4] Hematopoietic cells showed preferential distribution in a belt-like fashion on the surface of newly-formed bones in a bone regeneration model in the diaphysis of X. [5] In particular, the immune regulators underlying tendon regeneration are almost completely undetermined due to a paucity of tendon regeneration models. [6] Conclusion: The rabbit model is an efficient and reliable biological method for creating a seizable three-dimensional horizontal and vertical bone regeneration model in the mandibular ramus using osseous shell technique for testing various bone-substitute materials testing without compromising the health of the animal. [7] Both validation results show that compared to the single battery case, the working status of the battery is stabilized by the addition of the supercapacitor in the HESS case during both the propelling and regeneration modes and the battery energy is also saved. [8] Nerve regulation in regeneration has been investigated using the limb regeneration model and newly established alternative experimental model called the accessory limb model. [9] The sea anemone Nematostella vectensis is currently emerging as novel whole-body regeneration model. [10] The bone paste also supported bone healing in vivo in a guide bone regeneration model and, more interestingly, exhibited a substantial bone-forming ability when implanted in a critical-size defect model in rat calvaria. [11] CLDN3-/- mice had microscopically intact tight junctions, but showed significantly downregulated hepatic energy metabolism and suboptimal cell proliferation in the regeneration model. [12] We emphasize how these technologies have been applied to understand the dynamics of intestinal epithelial cells in homeostatic and injury-induced regeneration models. [13] Comprising the first step that takes ethanol to acetaldehyde, and a second step that converts acetaldehyde to acetyl-CoA, NADH from both steps could be mined for supporting biotransformation reaction in cofactor regeneration mode. [14] A computer framework, combining an automatic parametric scaffold design generation with a mechano-biological bone regeneration model, was developed to predict the level of regenerated bone volume for a large range of scaffold designs and to compare it with the scaffold pore volume fraction under favourable mechanical stimuli immediately after surgery. [15] The proposed topology employs series/parallel Lithium Ion Capacitor (LIC) controlled by bidirectional dc-dc converter during driving and regeneration modes. [16] The neonatal mice myocardial infarction (MI) has been established as one of the heart regeneration models. [17] used a CNS injury and regeneration model in which the optic nerve was crushed, resulting in neuronal death that was rescued by intraocular zymosan, which triggers myeloid cell repair processes. [18] In the latter one, local authorities-assuming potentially newurban regeneration models-pursue a strategic approach supporting bottom-up enhancement processes as a resource for the community development. [19] These results demonstrate the power and relevance of our novel ovine fetal tendon regeneration model, which thus promises to accelerate research in the field. [20] This work establishes the zebrafish vagus nerve as a tractable regeneration model and reveals the mechanistic basis of target-specific regeneration. [21] In the second part, we apply the stem cell regeneration model to dynamic hematological diseases, which are diseases associated with the dysregulation of hematopoiesis. [22] In this paper, three ideal regeneration models for liquid desiccant are established: thermal air (TA) regeneration, mechanical vapor recompression (MVR) regeneration and electrodialysis (ED) regeneration. [23] In order to address these issues and optimize the chondrogenic culture system, we generated a three-dimensional in vitro auricular cartilage regeneration model to investigate the effects of SP600125 (a JNK-specific inhibitor) on chondrocyte proliferation and ECM metabolism. [24] For the in vivo analysis, the chitosan scaffold was applied in a rodent orthotopic dental pulp regeneration model under the influence of PBMT (660 nm; power output of 20 mW, beam area of 0. [25] This comprehensive hypothetical framework that significantly extends the existing biological regeneration models offers a new way to conceptualise the information-processing aspects of regeneration, which may also help design living and non-living self-repairing agents. [26] A phase sensitive amplification (PSA) regeneration model for M-ary phase shift keying (MPSK) signals with amplified spontaneous emission (ASE) noise based on the interference between signal and its (M+1)th harmonic is proposed. [27] The use of LPCs was mostly studied in in vitro and in vivo craniofacial bone regeneration models. [28] The purpose of this study was to clarify the significance of ERs during fracture healing using osteoblast-specific ER knockout mice in a mono-cortical drill hole bone regeneration model. [29] The specific expression patterns of RRM2, TK1, CENPF, NUSAP1, UBE2C, and CDC20 were well correlated in a time- and cycle-dependent manner with proliferation stages in the cell growth and regeneration models. [30] The COP (the ratio of cooling load to energy consumption) of the absorption system with the solar steam mode is more than two times of that with the traditional regeneration mode. [31] Methods The ALPPS-induced regeneration model was established in livers with thioacetamide (TAA)-induced fibrosis to determine the regenerative pathways involved in rapid regeneration. [32] To this end, we established a partial hepatectomy regeneration model in adult zebrafish that express a liver-specific fluorescent reporter. [33] During de novo septation in a murine pneumonectomy lung regeneration model, developmental processes are reactivated within the iReFs, indicating progenitor function well into adulthood. [34] Therefore, in this preclinical study, we compared the bone regeneration ability of E-rhBMP-2/β-TCP and autogenous bone grafts in a canine guided-bone regeneration model. [35] In order to improve the uneven flow of exhaust in traditional catalytic gasoline particulate filter system (C-GPFs) and improve the regeneration performances under low-temperature conditions, the new C-GPFs integrated regeneration model is established and explored. [36] The speed estimator in combination with the proposed resistance estimator performs well in both motoring and regeneration modes. [37] The purpose of this study is to reveal the inhibitory effects of seaweed extracts, which are widely consumed in Korea, and alginic acid on muscle cell damage in muscle atrophy and regeneration models. [38] Here, using the mammalian neonatal heart regeneration model, we show that Nrf1, a stress-responsive transcription factor encoded by the Nuclear Factor Erythroid 2 Like 1 (Nfe2l1) gene, is activated in regenerating cardiomyocytes. [39] Planarians are flatworms that can regenerate any missing body part and their regenerative powers have combined with ease of experimentation to make them a classic regeneration model for more than a century. [40] [5] identified the required steps for ophthalmic research to conduct a valid retinal degeneration/regeneration model. [41] There has been increased interest in the study of lizard tail regeneration in recent years as it is an amenable regeneration model for amniotes. [42] A total of 17 studies, including two clinical trials and 15 animal studies using orthotopic pulp regeneration models, were included for the review. [43] In particular, the immune regulators underlying tendon regeneration are almost completely unknown due to a paucity of tendon regeneration models. [44] In this paper, we propose a bone regeneration model with angiogenesis based on the theories of mechanobiology regulation, vascular network modeling, oxygen-induced secretion of vascular endothelial growth factor (VEGF), and vascular remodeling. [45] The evaluation framework is part of an Urban Regeneration Model designed to accelerate the urban transformation toward the smart city concept, taking into account all aspects of sustainability. [46] With the goal of improving the vitality and quality of the city, it explores a progressive and sustainable organic regeneration model for the riverfront industrial zone. [47] In this review article, we summarize and discuss, from an evolutionary perspective, the recent data obtained for a variety of regeneration models which have allowed to identify key shared mechanisms that control these main steps of animal regeneration. [48] METHODS We characterized the Sox2 expression in olfactory GBCs in normal conditions and in a lesion-regeneration model using a Lgr5EGFP-IRES-creERT2 strain. [49]本文介绍了对从 20 个榜样 (RM) 案例研究中收集的数据进行分析的结果，这些案例研究涉及他们成功的以遗产为主导的乡村再生模式。 [1] 在本研究中，我们发现使用 miRNA PCR 阵列和维恩图分析在三种啮齿动物肝脏再生模型中 miR-20a 的表达显着降低。 [2] 因此，本研究提出了计划行为模型的扩展理论，该模型使用再生模式的优度（GRM）作为调节结构，并考虑环境关注（EC）和感知价值（PV）来确定影响公众接受行为意图（BI）的因素. [3] 本文介绍了基于斑马鱼的骨降解再生模型和体内OCT成像的构建。 [4] 在 X 骨干的骨再生模型中，造血细胞在新形成的骨表面呈带状优先分布。 [5] 特别是，由于缺乏肌腱再生模型，肌腱再生的免疫调节剂几乎完全未确定。 [6] 结论： 兔模型是一种有效且可靠的生物学方法，用于在不损害动物健康的情况下，利用骨壳技术在下颌支中创建可抓取的三维水平和垂直骨再生模型，用于测试各种骨替代材料测试。 [7] 两项验证结果均表明，与单电池箱相比，在推进和再生模式下，通过在HESS箱中添加超级电容器，电池的工作状态得到了稳定，同时也节省了电池能量。 [8] 已经使用肢体再生模型和新建立的称为附属肢体模型的替代实验模型研究了再生中的神经调节。 [9] 海葵 Nematostella vectensis 目前正在成为一种新型的全身再生模型。 [10] 该骨膏还在指导骨再生模型中支持体内骨愈合，更有趣的是，当植入大鼠颅盖骨的临界尺寸缺陷模型时，它表现出显着的骨形成能力。 [11] CLDN3-/- 小鼠在显微镜下具有完整的紧密连接，但在再生模型中表现出显着下调的肝能量代谢和次优细胞增殖。 [12] 我们强调如何应用这些技术来了解肠道上皮细胞在稳态和损伤诱导的再生模型中的动态。 [13] 包括将乙醇转化为乙醛的第一步和将乙醛转化为乙酰辅酶 A 的第二步，可以从这两个步骤中开采 NADH，以支持辅因子再生模式下的生物转化反应。 [14] 开发了一种计算机框架，将自动参数化支架设计生成与机械生物骨再生模型相结合，以预测大量支架设计的再生骨体积水平，并将其与有利机械条件下的支架孔体积分数进行比较手术后立即刺激。 [15] 所提出的拓扑采用串联/并联锂离子电容器 (LIC)，在驱动和再生模式期间由双向 DC-DC 转换器控制。 [16] 新生小鼠心肌梗死（MI）已被确立为心脏再生模型之一。 [17] 使用中枢神经系统损伤和再生模型，其中视神经被压碎，导致神经元死亡，被眼内酵母聚糖挽救，从而触发骨髓细胞修复过程。 [18] 在后一种情况下，地方当局——假设潜在的新城市更新模式——采用一种战略方法，支持自下而上的增强过程，作为社区发展的资源。 [19] 这些结果证明了我们新型羊胎肌腱再生模型的力量和相关性，因此有望加速该领域的研究。 [20] 这项工作将斑马鱼迷走神经建立为一种易于处理的再生模型，并揭示了目标特异性再生的机制基础。 [21] 在第二部分，我们将干细胞再生模型应用于动态血液疾病，即与造血功能失调相关的疾病。 [22] 本文建立了三种理想的液体干燥剂再生模型：热空气（TA）再生、机械蒸汽再压缩（MVR）再生和电渗析（ED）再生。 [23] 为了解决这些问题并优化软骨形成培养系统，我们建立了一个三维体外耳廓软骨再生模型，以研究 SP600125（一种 JNK 特异性抑制剂）对软骨细胞增殖和 ECM 代谢的影响。 [24] 对于体内分析，壳聚糖支架被应用于在PBMT（660 nm；功率输出为20 mW，光束面积为0）影响下的啮齿动物原位牙髓再生模型中。 [25] 这一全面的假设框架显着扩展了现有的生物再生模型，为概念化再生的信息处理方面提供了一种新方法，这也可能有助于设计有生命和无生命的自我修复剂。 [26] 基于信号与其(M+1)次谐波之间的干扰，提出了一种具有放大自发发射(ASE)噪声的M进制相移键控(MPSK)信号的相敏放大(PSA)再生模型。 [27] LPC 的使用主要在体外和体内颅面骨再生模型中进行研究。 [28] 本研究的目的是在单皮质钻孔骨再生模型中使用成骨细胞特异性 ER 敲除小鼠阐明 ER 在骨折愈合过程中的重要性。 [29] 在细胞生长和再生模型中，RRM2、TK1、CENPF、NUSAP1、UBE2C 和 CDC20 的特定表达模式以时间和周期依赖性方式与增殖阶段密切相关。 [30] 太阳能蒸汽模式吸收系统的COP（冷负荷与能耗之比）是传统再生模式的两倍以上。 [31] 方法 在硫代乙酰胺 (TAA) 诱导的肝纤维化中建立了 ALPPS 诱导的再生模型，以确定参与快速再生的再生途径。 [32] 为此，我们在成年斑马鱼中建立了部分肝切除再生模型，该模型表达了肝脏特异性荧光报告基因。 [33] 在小鼠全肺切除肺再生模型的从头分离过程中，iReFs 内的发育过程被重新激活，表明祖细胞功能很好地进入成年期。 [34] 因此，在这项临床前研究中，我们在犬引导骨再生模型中比较了 E-rhBMP-2/β-TCP 和自体骨移植物的骨再生能力。 [35] 为改善传统催化汽油微粒过滤器系统（C-GPFs）排气不均匀现象，提高低温条件下的再生性能，建立并探索了新的C-GPFs集成再生模型。 [36] 速度估计器与建议的阻力估计器相结合，在机动和再生模式下都表现良好。 [37] 本研究的目的是揭示在韩国广泛食用的海藻提取物和海藻酸对肌肉萎缩和再生模型中肌肉细胞损伤的抑制作用。 [38] 在这里，使用哺乳动物新生儿心脏再生模型，我们显示 Nrf1，一种由核因子红细胞 2 像 1 (Nfe2l1) 基因编码的应激反应转录因子，在再生心肌细胞中被激活。 [39] 涡虫是扁形虫，可以再生任何缺失的身体部位，它们的再生能力与易于实验相结合，使它们成为一个多世纪以来的经典再生模型。 [40] [5] 确定了眼科研究进行有效的视网膜变性/再生模型所需的步骤。 [41] 近年来，人们对蜥蜴尾巴再生的研究越来越感兴趣，因为它是一种适合羊膜动物的再生模型。 [42] 共纳入 17 项研究，包括两项临床试验和 15 项使用原位牙髓再生模型的动物研究。 [43] 特别是，由于缺乏肌腱再生模型，肌腱再生的免疫调节剂几乎完全未知。 [44] 在本文中，我们基于力学生物学调节、血管网络建模、氧诱导血管内皮生长因子（VEGF）分泌和血管重塑等理论，提出了一种具有血管生成的骨再生模型。 [45] 该评估框架是城市再生模型的一部分，旨在加速城市向智慧城市概念的转型，同时考虑到可持续性的各个方面。 [46] 以提升城市活力和品质为目标，探索滨河工业区渐进可持续的有机再生模式。 [47] 在这篇评论文章中，我们从进化的角度总结和讨论了最近为各种再生模型获得的数据，这些数据允许识别控制动物再生这些主要步骤的关键共享机制。 [48] 方法 我们在正常条件下和使用 Lgr5EGFP-IRES-creERT2 菌株的病变再生模型中表征了嗅觉 GBC 中的 Sox2 表达。 [49]
Bone Regeneration Mode
Hematopoietic cells showed preferential distribution in a belt-like fashion on the surface of newly-formed bones in a bone regeneration model in the diaphysis of X. [1] Conclusion: The rabbit model is an efficient and reliable biological method for creating a seizable three-dimensional horizontal and vertical bone regeneration model in the mandibular ramus using osseous shell technique for testing various bone-substitute materials testing without compromising the health of the animal. [2] The bone paste also supported bone healing in vivo in a guide bone regeneration model and, more interestingly, exhibited a substantial bone-forming ability when implanted in a critical-size defect model in rat calvaria. [3] A computer framework, combining an automatic parametric scaffold design generation with a mechano-biological bone regeneration model, was developed to predict the level of regenerated bone volume for a large range of scaffold designs and to compare it with the scaffold pore volume fraction under favourable mechanical stimuli immediately after surgery. [4] The use of LPCs was mostly studied in in vitro and in vivo craniofacial bone regeneration models. [5] The purpose of this study was to clarify the significance of ERs during fracture healing using osteoblast-specific ER knockout mice in a mono-cortical drill hole bone regeneration model. [6] Therefore, in this preclinical study, we compared the bone regeneration ability of E-rhBMP-2/β-TCP and autogenous bone grafts in a canine guided-bone regeneration model. [7] In this paper, we propose a bone regeneration model with angiogenesis based on the theories of mechanobiology regulation, vascular network modeling, oxygen-induced secretion of vascular endothelial growth factor (VEGF), and vascular remodeling. [8]在 X 骨干的骨再生模型中，造血细胞在新形成的骨表面呈带状优先分布。 [1] 结论： 兔模型是一种有效且可靠的生物学方法，用于在不损害动物健康的情况下，利用骨壳技术在下颌支中创建可抓取的三维水平和垂直骨再生模型，用于测试各种骨替代材料测试。 [2] 该骨膏还在指导骨再生模型中支持体内骨愈合，更有趣的是，当植入大鼠颅盖骨的临界尺寸缺陷模型时，它表现出显着的骨形成能力。 [3] 开发了一种计算机框架，将自动参数化支架设计生成与机械生物骨再生模型相结合，以预测大量支架设计的再生骨体积水平，并将其与有利机械条件下的支架孔体积分数进行比较手术后立即刺激。 [4] LPC 的使用主要在体外和体内颅面骨再生模型中进行研究。 [5] 本研究的目的是在单皮质钻孔骨再生模型中使用成骨细胞特异性 ER 敲除小鼠阐明 ER 在骨折愈合过程中的重要性。 [6] 因此，在这项临床前研究中，我们在犬引导骨再生模型中比较了 E-rhBMP-2/β-TCP 和自体骨移植物的骨再生能力。 [7] 在本文中，我们基于力学生物学调节、血管网络建模、氧诱导血管内皮生长因子（VEGF）分泌和血管重塑等理论，提出了一种具有血管生成的骨再生模型。 [8]
Tendon Regeneration Mode
In particular, the immune regulators underlying tendon regeneration are almost completely undetermined due to a paucity of tendon regeneration models. [1] These results demonstrate the power and relevance of our novel ovine fetal tendon regeneration model, which thus promises to accelerate research in the field. [2] In particular, the immune regulators underlying tendon regeneration are almost completely unknown due to a paucity of tendon regeneration models. [3]特别是，由于缺乏肌腱再生模型，肌腱再生的免疫调节剂几乎完全未确定。 [1] 这些结果证明了我们新型羊胎肌腱再生模型的力量和相关性，因此有望加速该领域的研究。 [2] 特别是，由于缺乏肌腱再生模型，肌腱再生的免疫调节剂几乎完全未知。 [3]
Induced Regeneration Mode
We emphasize how these technologies have been applied to understand the dynamics of intestinal epithelial cells in homeostatic and injury-induced regeneration models. [1] Methods The ALPPS-induced regeneration model was established in livers with thioacetamide (TAA)-induced fibrosis to determine the regenerative pathways involved in rapid regeneration. [2]我们强调如何应用这些技术来了解肠道上皮细胞在稳态和损伤诱导的再生模型中的动态。 [1] 方法 在硫代乙酰胺 (TAA) 诱导的肝纤维化中建立了 ALPPS 诱导的再生模型，以确定参与快速再生的再生途径。 [2]
Heart Regeneration Mode
The neonatal mice myocardial infarction (MI) has been established as one of the heart regeneration models. [1] Here, using the mammalian neonatal heart regeneration model, we show that Nrf1, a stress-responsive transcription factor encoded by the Nuclear Factor Erythroid 2 Like 1 (Nfe2l1) gene, is activated in regenerating cardiomyocytes. [2]新生小鼠心肌梗死（MI）已被确立为心脏再生模型之一。 [1] 在这里，使用哺乳动物新生儿心脏再生模型，我们显示 Nrf1，一种由核因子红细胞 2 像 1 (Nfe2l1) 基因编码的应激反应转录因子，在再生心肌细胞中被激活。 [2]
Pulp Regeneration Mode
For the in vivo analysis, the chitosan scaffold was applied in a rodent orthotopic dental pulp regeneration model under the influence of PBMT (660 nm; power output of 20 mW, beam area of 0. [1] A total of 17 studies, including two clinical trials and 15 animal studies using orthotopic pulp regeneration models, were included for the review. [2]对于体内分析，壳聚糖支架被应用于在PBMT（660 nm；功率输出为20 mW，光束面积为0）影响下的啮齿动物原位牙髓再生模型中。 [1] 共纳入 17 项研究，包括两项临床试验和 15 项使用原位牙髓再生模型的动物研究。 [2]