Regenerated Silk(再生丝)研究综述
Regenerated Silk 再生丝 - The hydrogel with high bonding strength to the wet surface was prepared using a crosslinked network of alginate-dopamine, chondroitin sulfate, and regenerated silk fibroin (AD/CS/RSF). [1] In this work, we designed and fabricated an antibacterial opto-electro sensing suture (OESS) based on regenerated silk fibroin. [2] Regenerated silk fibroin (SF) has excellent biocompatibility and degradability, but its mechanical properties need to be improved. [3] In this study, we report the fabrication of two different three-dimensional (3D) architectures of regenerated silk (RS) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) with embedded functionalities. [4] The molecular weight (MW) of regenerated silk fibroin (RSF) decreases during degumming and dissolving processes. [5] In this study, regenerated silk fibroin (RSF)/cellulose nanofibers (CNF) hybrid fibers were wet-spun through a microfluidic channel that mimics the shape of spider’s major ampullate gland. [6] In the present study, a robust regenerated silk fibroin (RSF)-based hydrogel was fabricated with silver nanowires (AgNWs) embedded in the surface. [7] The regenerated silk solution that results from silk processing may then be converted into a multitude of forms like gels, foams, nanoparticles, and wafers. [8] The initial SMLs are patterned by casting laser dye-doped regenerated silk fibroin solution, resulting in a uniform microlaser array with regulated positions. [9] Here a unique strategy was investigated to maintain microgels together with a novel self-reinforced silk granular hydrogel composed of 10 wt% 20 kDa poly(ethylene glycol) dimethacrylate microgels and regenerated silk fibroin fibers. [10] Herein, hyaluronic acid (HA)-functionalized regenerated silk fibroin-based nanoparticles (NPs) were used to concurrently deliver curcumin (CUR) and 5-fluorouracil (5-FU) at various weight ratios (3. [11] Reduced graphene oxide/titanium dioxide ([email protected]) hybrid nanoparticle was synthesized and used as a filler to study the synergistic effects on electrospun regenerated silk fibroin (RSF) mats. [12] In addition, the silk nanocrystal-based hydrogel exhibited outstanding mechanical properties compared to those of dissolved and regenerated silk fibroin-based hydrogels. [13] Herein, a chemotherapeutic drug (doxorubicin, Dox) and a manganese ion (Mn2+) were co-loaded into regenerated silk fibroin-based nanoparticles (NPs), followed by the surface conjugation of phycocyanin (PC) to construct tumor microenvironment-activated nanococktails. [14] In this study, regenerated silk (RS) obtained from Bombyx Mori cocoons is compounded with carboxyl-functionalized carbon nanotubes (f-CNTs) in an aqueous environment for the fabrication of functional bio-adhesives. [15] In this work, poly(hydroxymethyl-3,4-ethylenedioxythiophene) (PEDOT-OH) was chemically polymerized and deposited on the surface of a regenerated silk fibroin (RSF) film in an aqueous system. [16] This study aims to utilize the thermosetting behavior of native lignin and the self-assembly of silk in coconut coir (CC) and regenerated silk (RS) microparticles used as blends and natural binders for construction and demolition waste (CDW) wood and their effect on the mechanical, thermal, and structural properties of CDW wood/CC, RS/CC, and CDW wood/RS biomicrocomposites. [17] In this research，a series of photochromic hybrid fibers composed of regenerated silk fibroin (RSF) and WO3 NPs with different mass ratios have been prepared by wet spinning, which endowed the hybrid fibers with enhanced mechanical properties and excellent photochromic properties. [18] Based on these characteristics, we fabricated advanced double-layered adhesive microneedle bandages (DL-AMNBs) consisting of a biofunctional MAP-based root and a regenerated silk fibroin (SF)-based tip, allowing homogeneous distribution of the regenerative factor via swellable microneedles. [19] The regenerated silk fibroin (RSF)-based microfluidic device has attracted tremendous interests in recent years due to its excellent biocompatibility, mild processing conditions, and all aqueous casting production. [20] In this study, we report the fabrication of two different three-dimensional (3D) architectures of regenerated silk (RS) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) with embedded functionalities. [21] Regenerated Silk Fibroin (RSF) films are considered promising substrate candidates primarily in the field of bio-integrated electronic device applications. [22] Regenerated silk nanofibers are interesting as protein-based material building blocks due to their unique structure and biological origin. [23] A highly oriented molecular network structure (HOMNS) is a common and favorable design in natural and regenerated silks to achieve self-reinforcement of the material. [24] We report a rewritable bio-drive using naturally regenerated silk proteins as the optical storage medium (termed as “silk-drive”) using a home-built tip-enhanced nearfield infrared optics system for both “write” & “read” information. [25] Following the successful dissolution of the fibroin, the regenerated silk fibroin solutions were cast to obtain water insoluble films which were used in investigating optimum electrospinning conditions. [26] Here, we report biocompatible adhesives obtained by blending regenerated silk (RS) with a soluble plant-derived polyphenol (i. [27] In this work, to solve the intrinsic brittleness as well as poor chemical stability of pure silk fibroin film, mesoscopic doping of regenerated silk fibroin is introduced to promote the secondary structure transformation, resulting in huge improvement in mechanical flexibility (∼250% stretchable and 1000 bending cycles) and chemical stability (endure 100 °C and 3-11 pH). [28] This chapter describes methods to produce regenerated silk fibroin protein from Bombyx mori silk and their self-assembly strategies. [29] Thus, this work investigates a novel procedure for the isolation of non-degraded regenerated silk fibroin that significantly reduces the processing time from 52 h for the standard methods to only 4 h. [30] In this study, we aimed to formulate injectable hydrogels for drug delivery and cartilage tissue engineering by combining different concentrations of hyaluronic acid-tyramine (HA-Tyr) with regenerated silk-fibroin (SF) solutions. [31] Herein, LAPONITE® (LAP) nanoplatelets, a bioactive clay with good osteoinductivity, were incorporated within a regenerated silk fibroin (RSF) microfibrous mat via electrospinning. [32] The performance is comparable or even higher than that of many recombinant spider silks or regenerated silkworm fibers. [33] To overcome this issue, a one-pot assembly approach was developed to trap graphene inside electrospun mats of regenerated silk fibroin (RSF) by applying its ethanol-treatment driven supercontract. [34] Immersed in water, regenerated silk sericin formed a 100-µm-sized exclusion zone (for micron-size foulants), along with a proton gradient with a decrease of >2 pH-units. [35] In this work, regenerated silk fibroin (SF)/poly-L-lactic acid (PLLA) composite electrospun fibers were successfully prepared by electrospinning method with single and double syringe systems. [36] Regenerated silk (RS) is a natural polymer that results from the aggregation of liquid silk fibroin proteins. [37] Recently, regenerated silk fibroin is one of the most investigated silk-based materials for tissue engineering. [38] A silk-based small-caliber tubular scaffold (SFTS), which is fabricated using a regenerated silk fibroin porous scaffold embedding a silk fabric core layer, has been proved to possess good cell compatibility and mechanical properties in vitro. [39] We bundled together tail hairs of the rhino’s ubiquitous near relative, the horse, to be glued together with a bespoke matrix of regenerated silk mimicking the collagenous component of the real horn. [40] Natural and regenerated silk materials can also be transformed into intrinsically nitrogen-doped and electrically conductive carbon materials, due to their unique molecular structure and high nitrogen content. [41] SFNs were prepared with regenerated silk fibroin using desolvation method with fluorescein isothiocyanate labeled bovine serum albumin (FITC-BSA) as bio-macromolecular model drug encapsulated. [42] The possibility of spinning regenerated silkworm (Bombyx mori) fibers from a range of aqueous dopes by using a biomimetic approach based on straining flow spinning is explored in this work. [43] Herein, a catalytic system based on the regenerated silk fibroin (SF) gel integrated with cobalt tetraaminophthalocyanine (CoTAPc)-grafted-reduced graphene oxide (RGO) sheets were fabricated, and its catalytic activity was assessed via the degradation of acid red G (ARG) at varying catalyst and H2O2 dosages, pH values, and temperatures. [44] In this work, regenerated silk fibroin (RSF) and silicon dioxide (SiO2) composite fiber was successfully extruded by wet spinning method. [45] These bioinspired and biomimetic strategies significantly improved the mechanical performance of the regenerated silk fibers and provided possibility for further functionalization of the fibers. [46] Objective: The aim of this study was to develop chitosan/regenerated silk fibroin (CS/RSF) films as a biomaterial for contact lenses-based ophthalmic drug delivery system. [47] Therefore, we proposed herein a novel highly interconnected suturable porous scaffolds from regenerated silk fibroin that is reinforced with 3D-printed polycaprolactone (PCL) mesh in the middle, on the transverse plane to enhance the suture-holding capacity. [48] Recently, fabricating various functional silk fibers and regenerated silk protein biomaterials which has ability of releasing functional protein factor is the hot point field. [49] Here we report a thermal processing method for the direct solid-state moulding of regenerated silk into bulk ‘parts’ or devices with tunable mechanical properties. [50]使用海藻酸盐-多巴胺、硫酸软骨素和再生丝素蛋白 (AD/CS/RSF) 的交联网络制备对湿表面具有高粘合强度的水凝胶。 [1] 在这项工作中，我们设计并制造了一种基于再生丝素蛋白的抗菌光电传感缝合线（OESS）。 [2] 再生丝素蛋白（SF）具有优异的生物相容性和降解性，但其力学性能有待提高。 [3] 在这项研究中，我们报告了具有嵌入功能的再生丝 (RS) 和聚 (3-羟基丁酸酯-co-3-羟基戊酸酯) (PHBV) 的两种不同三维 (3D) 架构的制造。 [4] 在脱胶和溶解过程中，再生丝素蛋白 (RSF) 的分子量 (MW) 会降低。 [5] 在这项研究中，再生丝素蛋白 (RSF)/纤维素纳米纤维 (CNF) 混合纤维通过模拟蜘蛛主要壶状腺形状的微流体通道进行湿纺。 [6] 在本研究中，用嵌入表面的银纳米线 (AgNWs) 制造了一种坚固的再生丝素蛋白 (RSF) 基水凝胶。 [7] 由丝加工产生的再生丝溶液随后可以转化为多种形式，如凝胶、泡沫、纳米颗粒和晶片。 [8] 最初的 SML 通过铸造激光染料掺杂的再生丝素蛋白溶液进行图案化，从而形成具有受管制位置的均匀微激光阵列。 [9] 在这里，研究了一种独特的策略来维持微凝胶以及由 10 wt% 20 kDa 聚 (乙二醇) 二甲基丙烯酸酯微凝胶和再生丝素纤维组成的新型自增强丝粒状水凝胶。 [10] 在此，透明质酸 (HA) 功能化的再生丝素基纳米粒子 (NPs) 用于同时递送不同重量比的姜黄素 (CUR) 和 5-氟尿嘧啶 (5-FU) (3. [11] 合成了还原氧化石墨烯/二氧化钛 ([email protected]) 杂化纳米颗粒，并将其用作填料，以研究电纺再生丝素蛋白 (RSF) 垫的协同效应。 [12] 此外，与溶解和再生的基于丝素蛋白的水凝胶相比，基于丝纳米晶的水凝胶表现出出色的机械性能。 [13] 在此，一种化学治疗药物（阿霉素，Dox）和一种锰离子（Mn2+）被共同加载到基于再生丝素蛋白的纳米颗粒（NPs）中，然后通过藻蓝蛋白（PC）的表面共轭构建肿瘤微环境激活的纳米鸡尾酒。 [14] 在这项研究中，从 Bombyx Mori 茧中获得的再生丝 (RS) 在水环境中与羧基官能化碳纳米管 (f-CNT) 复合，用于制造功能性生物粘合剂。 [15] 在这项工作中，poly(hydroxymethyl-3,4-ethylenedioxythiophene) (PEDOT-OH) 被化学聚合并沉积在含水系统中的再生丝素蛋白 (RSF) 薄膜的表面上。 [16] 本研究旨在利用天然木质素的热固性行为和椰子椰壳 (CC) 和再生丝 (RS) 微粒中丝的自组装特性，这些微粒用作建筑和拆除废料 (CDW) 木材的混合物和天然粘合剂，以及它们对CDW 木材/CC、RS/CC 和 CDW 木材/RS 生物微复合材料的机械、热和结构特性。 [17] 本研究通过湿法纺丝制备了一系列由不同质量比的再生丝素蛋白（RSF）和WO3 NPs组成的光致变色杂化纤维，赋予杂化纤维增强的力学性能和优异的光致变色性能。 [18] 基于这些特性，我们制造了先进的双层粘性微针绷带 (DL-AMNBs)，该绷带由基于 MAP 的生物功能根和基于再生丝素蛋白 (SF) 的尖端组成，可通过可膨胀的微针均匀分布再生因子。 [19] 近年来，基于再生丝素蛋白（RSF）的微流控装置因其优异的生物相容性、温和的加工条件和全水性浇注生产而引起了极大的兴趣。 [20] 在这项研究中，我们报告了具有嵌入功能的再生丝 (RS) 和聚 (3-羟基丁酸酯-co-3-羟基戊酸酯) (PHBV) 的两种不同三维 (3D) 架构的制造。 [21] 再生丝素蛋白 (RSF) 薄膜被认为主要在生物集成电子设备应用领域中很有前景的候选基材。 [22] 由于其独特的结构和生物来源，再生丝纳米纤维作为基于蛋白质的材料构建块很有趣。 [23] 高度定向的分子网络结构（HOMNS）是天然和再生丝绸中一种常见且有利的设计，可实现材料的自我增强。 [24] 我们报告了一种可重写的生物驱动器，它使用天然再生的丝蛋白作为光存储介质（称为“丝绸驱动器”），使用自制的尖端增强近场红外光学系统来“写入”和“读取”信息。 [25] 在成功溶解丝素蛋白后，将再生的丝素蛋白溶液浇铸以获得水不溶性薄膜，用于研究最佳静电纺丝条件。 [26] 在这里，我们报告了通过将再生丝 (RS) 与可溶性植物衍生多酚 (i. [27] 在这项工作中，为了解决纯丝素膜固有的脆性和较差的化学稳定性，引入了再生丝素蛋白的介观掺杂以促进二级结构转变，从而极大地提高了机械柔韧性（~250% 可拉伸和 1000弯曲循环）和化学稳定性（耐受 100 °C 和 3-11 pH）。 [28] 本章介绍了从家蚕丝中生产再生丝素蛋白的方法及其自组装策略。 [29] 因此，这项工作研究了一种分离非降解再生丝素蛋白的新方法，该方法将处理时间从标准方法的 52 小时显着减少到仅 4 小时。 [30] 在这项研究中，我们旨在通过将不同浓度的透明质酸-酪胺 (HA-Tyr) 与再生丝素 (SF) 溶液相结合，配制用于药物输送和软骨组织工程的可注射水凝胶。 [31] 在这里，LAPONITE® (LAP) 纳米血小板是一种具有良好骨诱导性的生物活性粘土，通过静电纺丝被掺入再生的丝素蛋白 (RSF) 微纤维垫中。 [32] nan [33] nan [34] nan [35] nan [36] nan [37] nan [38] nan [39] nan [40] nan [41] nan [42] nan [43] nan [44] nan [45] nan [46] nan [47] nan [48] nan [49] nan [50]
regenerated silk fibroin
The hydrogel with high bonding strength to the wet surface was prepared using a crosslinked network of alginate-dopamine, chondroitin sulfate, and regenerated silk fibroin (AD/CS/RSF). [1] In this work, we designed and fabricated an antibacterial opto-electro sensing suture (OESS) based on regenerated silk fibroin. [2] Regenerated silk fibroin (SF) has excellent biocompatibility and degradability, but its mechanical properties need to be improved. [3] The molecular weight (MW) of regenerated silk fibroin (RSF) decreases during degumming and dissolving processes. [4] In this study, regenerated silk fibroin (RSF)/cellulose nanofibers (CNF) hybrid fibers were wet-spun through a microfluidic channel that mimics the shape of spider’s major ampullate gland. [5] In the present study, a robust regenerated silk fibroin (RSF)-based hydrogel was fabricated with silver nanowires (AgNWs) embedded in the surface. [6] The initial SMLs are patterned by casting laser dye-doped regenerated silk fibroin solution, resulting in a uniform microlaser array with regulated positions. [7] Here a unique strategy was investigated to maintain microgels together with a novel self-reinforced silk granular hydrogel composed of 10 wt% 20 kDa poly(ethylene glycol) dimethacrylate microgels and regenerated silk fibroin fibers. [8] Herein, hyaluronic acid (HA)-functionalized regenerated silk fibroin-based nanoparticles (NPs) were used to concurrently deliver curcumin (CUR) and 5-fluorouracil (5-FU) at various weight ratios (3. [9] Reduced graphene oxide/titanium dioxide ([email protected]) hybrid nanoparticle was synthesized and used as a filler to study the synergistic effects on electrospun regenerated silk fibroin (RSF) mats. [10] In addition, the silk nanocrystal-based hydrogel exhibited outstanding mechanical properties compared to those of dissolved and regenerated silk fibroin-based hydrogels. [11] Herein, a chemotherapeutic drug (doxorubicin, Dox) and a manganese ion (Mn2+) were co-loaded into regenerated silk fibroin-based nanoparticles (NPs), followed by the surface conjugation of phycocyanin (PC) to construct tumor microenvironment-activated nanococktails. [12] In this work, poly(hydroxymethyl-3,4-ethylenedioxythiophene) (PEDOT-OH) was chemically polymerized and deposited on the surface of a regenerated silk fibroin (RSF) film in an aqueous system. [13] In this research，a series of photochromic hybrid fibers composed of regenerated silk fibroin (RSF) and WO3 NPs with different mass ratios have been prepared by wet spinning, which endowed the hybrid fibers with enhanced mechanical properties and excellent photochromic properties. [14] Based on these characteristics, we fabricated advanced double-layered adhesive microneedle bandages (DL-AMNBs) consisting of a biofunctional MAP-based root and a regenerated silk fibroin (SF)-based tip, allowing homogeneous distribution of the regenerative factor via swellable microneedles. [15] The regenerated silk fibroin (RSF)-based microfluidic device has attracted tremendous interests in recent years due to its excellent biocompatibility, mild processing conditions, and all aqueous casting production. [16] Regenerated Silk Fibroin (RSF) films are considered promising substrate candidates primarily in the field of bio-integrated electronic device applications. [17] Following the successful dissolution of the fibroin, the regenerated silk fibroin solutions were cast to obtain water insoluble films which were used in investigating optimum electrospinning conditions. [18] In this work, to solve the intrinsic brittleness as well as poor chemical stability of pure silk fibroin film, mesoscopic doping of regenerated silk fibroin is introduced to promote the secondary structure transformation, resulting in huge improvement in mechanical flexibility (∼250% stretchable and 1000 bending cycles) and chemical stability (endure 100 °C and 3-11 pH). [19] This chapter describes methods to produce regenerated silk fibroin protein from Bombyx mori silk and their self-assembly strategies. [20] Thus, this work investigates a novel procedure for the isolation of non-degraded regenerated silk fibroin that significantly reduces the processing time from 52 h for the standard methods to only 4 h. [21] Herein, LAPONITE® (LAP) nanoplatelets, a bioactive clay with good osteoinductivity, were incorporated within a regenerated silk fibroin (RSF) microfibrous mat via electrospinning. [22] To overcome this issue, a one-pot assembly approach was developed to trap graphene inside electrospun mats of regenerated silk fibroin (RSF) by applying its ethanol-treatment driven supercontract. [23] In this work, regenerated silk fibroin (SF)/poly-L-lactic acid (PLLA) composite electrospun fibers were successfully prepared by electrospinning method with single and double syringe systems. [24] Recently, regenerated silk fibroin is one of the most investigated silk-based materials for tissue engineering. [25] A silk-based small-caliber tubular scaffold (SFTS), which is fabricated using a regenerated silk fibroin porous scaffold embedding a silk fabric core layer, has been proved to possess good cell compatibility and mechanical properties in vitro. [26] SFNs were prepared with regenerated silk fibroin using desolvation method with fluorescein isothiocyanate labeled bovine serum albumin (FITC-BSA) as bio-macromolecular model drug encapsulated. [27] Herein, a catalytic system based on the regenerated silk fibroin (SF) gel integrated with cobalt tetraaminophthalocyanine (CoTAPc)-grafted-reduced graphene oxide (RGO) sheets were fabricated, and its catalytic activity was assessed via the degradation of acid red G (ARG) at varying catalyst and H2O2 dosages, pH values, and temperatures. [28] In this work, regenerated silk fibroin (RSF) and silicon dioxide (SiO2) composite fiber was successfully extruded by wet spinning method. [29] Objective: The aim of this study was to develop chitosan/regenerated silk fibroin (CS/RSF) films as a biomaterial for contact lenses-based ophthalmic drug delivery system. [30] Therefore, we proposed herein a novel highly interconnected suturable porous scaffolds from regenerated silk fibroin that is reinforced with 3D-printed polycaprolactone (PCL) mesh in the middle, on the transverse plane to enhance the suture-holding capacity. [31] Overcoming these limitations, in this study, we report the successful blending of regenerated silk fibroin with a medical-grade, non-degradable polyurethane using formic acid and dichloromethane, and the manufacturing of hybrid, semi-degradable electrospun tubular meshes with different ratios of the two materials. [32] Objective: To characterize the morphology of chondrocytes and the expression and secretion of active collagen II by these cells cultured within a regenerated silk fibroin film. [33] Herein, based on regenerated silk fibroin dissolved in ferric chloride and zinc chloride aqueous solution, 2D porous carbon nanosheets with atomically-dispersed Fe-Nx -C active sites and very large specific surface area (≈2105 m2 g-1 ) are prepared through a simple thermal treatment process. [34] For producing regenerated silk fibroin (RSF) fibers, the conformation transition of silk fibroin needs to be thoroughly studied during the spinning process. [35] Regenerated silk fibroin (RSF) is emerging as promising biomaterial for regeneration, drug delivery and optical devices, with continued demand for mild, all-aqueous processes to control microstructure and the performance. [36]使用海藻酸盐-多巴胺、硫酸软骨素和再生丝素蛋白 (AD/CS/RSF) 的交联网络制备对湿表面具有高粘合强度的水凝胶。 [1] 在这项工作中，我们设计并制造了一种基于再生丝素蛋白的抗菌光电传感缝合线（OESS）。 [2] 再生丝素蛋白（SF）具有优异的生物相容性和降解性，但其力学性能有待提高。 [3] 在脱胶和溶解过程中，再生丝素蛋白 (RSF) 的分子量 (MW) 会降低。 [4] 在这项研究中，再生丝素蛋白 (RSF)/纤维素纳米纤维 (CNF) 混合纤维通过模拟蜘蛛主要壶状腺形状的微流体通道进行湿纺。 [5] 在本研究中，用嵌入表面的银纳米线 (AgNWs) 制造了一种坚固的再生丝素蛋白 (RSF) 基水凝胶。 [6] 最初的 SML 通过铸造激光染料掺杂的再生丝素蛋白溶液进行图案化，从而形成具有受管制位置的均匀微激光阵列。 [7] 在这里，研究了一种独特的策略来维持微凝胶以及由 10 wt% 20 kDa 聚 (乙二醇) 二甲基丙烯酸酯微凝胶和再生丝素纤维组成的新型自增强丝粒状水凝胶。 [8] 在此，透明质酸 (HA) 功能化的再生丝素基纳米粒子 (NPs) 用于同时递送不同重量比的姜黄素 (CUR) 和 5-氟尿嘧啶 (5-FU) (3. [9] 合成了还原氧化石墨烯/二氧化钛 ([email protected]) 杂化纳米颗粒，并将其用作填料，以研究电纺再生丝素蛋白 (RSF) 垫的协同效应。 [10] 此外，与溶解和再生的基于丝素蛋白的水凝胶相比，基于丝纳米晶的水凝胶表现出出色的机械性能。 [11] 在此，一种化学治疗药物（阿霉素，Dox）和一种锰离子（Mn2+）被共同加载到基于再生丝素蛋白的纳米颗粒（NPs）中，然后通过藻蓝蛋白（PC）的表面共轭构建肿瘤微环境激活的纳米鸡尾酒。 [12] 在这项工作中，poly(hydroxymethyl-3,4-ethylenedioxythiophene) (PEDOT-OH) 被化学聚合并沉积在含水系统中的再生丝素蛋白 (RSF) 薄膜的表面上。 [13] 本研究通过湿法纺丝制备了一系列由不同质量比的再生丝素蛋白（RSF）和WO3 NPs组成的光致变色杂化纤维，赋予杂化纤维增强的力学性能和优异的光致变色性能。 [14] 基于这些特性，我们制造了先进的双层粘性微针绷带 (DL-AMNBs)，该绷带由基于 MAP 的生物功能根和基于再生丝素蛋白 (SF) 的尖端组成，可通过可膨胀的微针均匀分布再生因子。 [15] 近年来，基于再生丝素蛋白（RSF）的微流控装置因其优异的生物相容性、温和的加工条件和全水性浇注生产而引起了极大的兴趣。 [16] 再生丝素蛋白 (RSF) 薄膜被认为主要在生物集成电子设备应用领域中很有前景的候选基材。 [17] 在成功溶解丝素蛋白后，将再生的丝素蛋白溶液浇铸以获得水不溶性薄膜，用于研究最佳静电纺丝条件。 [18] 在这项工作中，为了解决纯丝素膜固有的脆性和较差的化学稳定性，引入了再生丝素蛋白的介观掺杂以促进二级结构转变，从而极大地提高了机械柔韧性（~250% 可拉伸和 1000弯曲循环）和化学稳定性（耐受 100 °C 和 3-11 pH）。 [19] 本章介绍了从家蚕丝中生产再生丝素蛋白的方法及其自组装策略。 [20] 因此，这项工作研究了一种分离非降解再生丝素蛋白的新方法，该方法将处理时间从标准方法的 52 小时显着减少到仅 4 小时。 [21] 在这里，LAPONITE® (LAP) 纳米血小板是一种具有良好骨诱导性的生物活性粘土，通过静电纺丝被掺入再生的丝素蛋白 (RSF) 微纤维垫中。 [22] nan [23] nan [24] nan [25] nan [26] nan [27] nan [28] nan [29] nan [30] nan [31] nan [32] nan [33] nan [34] nan [35] nan [36]
regenerated silk material
Natural and regenerated silk materials can also be transformed into intrinsically nitrogen-doped and electrically conductive carbon materials, due to their unique molecular structure and high nitrogen content. [1] Flexible and water-insoluble regenerated silk materials have caught considerable interest due to their mechanical properties and numerous potential applications in medical fields. [2]regenerated silk protein
We report a rewritable bio-drive using naturally regenerated silk proteins as the optical storage medium (termed as “silk-drive”) using a home-built tip-enhanced nearfield infrared optics system for both “write” & “read” information. [1] Recently, fabricating various functional silk fibers and regenerated silk protein biomaterials which has ability of releasing functional protein factor is the hot point field. [2]我们报告了一种可重写的生物驱动器，它使用天然再生的丝蛋白作为光存储介质（称为“丝绸驱动器”），使用自制的尖端增强近场红外光学系统来“写入”和“读取”信息。 [1] nan [2]