Producing Extended Spectrum(产生扩展频谱)研究综述
Producing Extended Spectrum 产生扩展频谱 - Wastewater is considered a hotspot niche of multi-drug and pathogenic bacteria such as Enterobacteriaceae-producing extended-spectrum beta-lactamases (ESBL-E). [1] coli strains producing extended-spectrum beta- lactamases (ESBLs) and plasmid-mediated Amp-C-beta -lactamase, and by using multiplex polymerase chain reaction (multiplex PCR) to confirm the presence of ESBL genes (class A): blaCTX-M(1;2;8;9;25), bla TEM, bla SHV , bla OXA and genes encoding AmpC-type beta lactamase (class C): bla MOX-1;2 , bla CMY- (1;2-7;8-11) , blaLAT-(1;4) ,bla DHA-(1;2), bla ACC, bla FOX-(1-5B) ,bla MIR-1 ,bla ACT-1. [2] Aim: The aim of this study was to develop combination approach for the treatment of Escherichia coli-producing extended-spectrum β-lactamases (ESBLs) isolated from intensive care unit (ICU)-acquired urinary tract infections (UTIs). [3] In the bovine sector, the spread of Enterobacterales producing extended-spectrum and AmpC β-lactamases (ESBL/AmpC) mostly concerns veal calves, and the use of waste milk containing antibiotic residues has been recurrently incriminated. [4] aureus and GNB producing extended-spectrum β-lactamases, mainly of the CTX-M variety. [5] coli producing extended-spectrum β-lactamases (ESBL). [6] The aim of the study was to evaluate the occurrence of Escherichia coli producing extended-spectrum betalactamases (ESBL and/or AmpC) in the milk of cows with mastitis. [7] OBJECTIVE To investigate the prevalence of multidrug-resistant (MDR) Pseudomonas aeruginosa (PA) producing extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs) in burn patients in Algeria. [8] The worldwide spread of Klebsiella pneumoniae producing extended-spectrum β-lactamase (ESBL-Kp) is a significant threat. [9] Several studies have noted the presence of bacteria producing extended-spectrum beta-lactamase, with the presence of antibiotic-resistance genes in fresh vegetables and fruits. [10] Aim: This study determined the occurrence of UPEC producing extended-spectrum β-lactamases (ESBLs), the genes conferring resistance to β-lactams, and the phylogenetic groups associated with ESBLs in Kenyan UPECs. [11]废水被认为是多药和致病细菌的热点生态位，例如产肠杆菌科的超广谱β-内酰胺酶（ESBL-E）。 [1] 大肠杆菌菌株产生超广谱β-内酰胺酶（ESBLs）和质粒介导的Amp-C-β-内酰胺酶，并通过使用多重聚合酶链反应（多重PCR）确认ESBL基因（A类）的存在：blaCTX-M (1;2;8;9;25), bla TEM, bla SHV, bla OXA 和编码 AmpC 型 β 内酰胺酶 (C 类) 的基因：bla MOX-1;2, bla CMY- (1;2-7; 8-11)、blaLAT-(1;4)、bla DHA-(1;2)、bla ACC、bla FOX-(1-5B)、bla MIR-1、bla ACT-1。 [2] 目的：本研究的目的是开发用于治疗从重症监护病房 (ICU) 获得性尿路感染 (UTI) 中分离出的产大肠杆菌的超广谱 β-内酰胺酶 (ESBL) 的联合方法。 [3] 在牛部门，产生超广谱和 AmpC β-内酰胺酶 (ESBL/AmpC) 的肠杆菌的传播主要涉及小牛肉，并且使用含有抗生素残留物的废牛奶经常受到指控。 [4] 金黄色葡萄球菌和 GNB 产生超广谱 β-内酰胺酶，主要是 CTX-M 品种。 [5] 产超广谱β-内酰胺酶（ESBL）的大肠杆菌。 [6] 该研究的目的是评估产超广谱β内酰胺酶（ESBL和/或AmpC）的大肠杆菌在患有乳腺炎的奶牛的乳汁中的发生率。 [7] 客观的 调查阿尔及利亚烧伤患者中产生超广谱 β-内酰胺酶 (ESBL) 和金属-β-内酰胺酶 (MBL) 的多药耐药 (MDR) 铜绿假单胞菌 (PA) 的流行情况。 [8] 产生超广谱 β-内酰胺酶 (ESBL-Kp) 的肺炎克雷伯菌在全球范围内的传播是一个重大威胁。 [9] 几项研究已经注意到存在产生超广谱β-内酰胺酶的细菌，并且在新鲜蔬菜和水果中存在抗生素抗性基因。 [10] 目的：本研究确定了肯尼亚 UPEC 中产生超广谱 β-内酰胺酶 (ESBL) 的 UPEC、赋予 β-内酰胺抗性的基因以及与 ESBL 相关的系统发育组。 [11]
Coli Producing Extended Spectrum
Objective To investigate the risk factors for drug resistance of urinary tract infections-causing Escherichia coli producing extended spectrum beta-Lactamases (ESBLs) in elderly people (≥65 years old), in order to provide evidence for rational use of antibiotics in clinic. [1] 63%), escherichia coli producing extended spectrum beta lactamases (ESBLs) (15. [2]客观的 探讨老年人（≥65岁）泌尿道感染产超广谱β-内酰胺酶（ESBLs）大肠埃希菌耐药的危险因素，为临床合理使用抗生素提供依据。 [1] 63%），大肠杆菌产生超广谱β内酰胺酶（ESBLs）（15。 [2]
producing extended spectrum betum
Objective To investigate the risk factors for drug resistance of urinary tract infections-causing Escherichia coli producing extended spectrum beta-Lactamases (ESBLs) in elderly people (≥65 years old), in order to provide evidence for rational use of antibiotics in clinic. [1] Strains producing extended spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new treatment and prevention strategies are urgently required, due to severely limited therapeutic options. [2] 63%), escherichia coli producing extended spectrum beta lactamases (ESBLs) (15. [3]客观的 探讨老年人（≥65岁）泌尿道感染产超广谱β-内酰胺酶（ESBLs）大肠埃希菌耐药的危险因素，为临床合理使用抗生素提供依据。 [1] 产生超广谱β-内酰胺酶（ESBLs）或碳青霉烯酶的菌株被认为是全球优先病原体，由于治疗选择严重受限，迫切需要新的治疗和预防策略。 [2] 63%），大肠杆菌产生超广谱β内酰胺酶（ESBLs）（15。 [3]
producing extended spectrum β
Drug resistant bacteria such as those producing extended spectrum β-lactamases (ESBL) and carbapenemases (KPC-2 and NDM-1), and those exhibiting colistin resistance (mcr-1) and tigecycline were included in this study. [1] coli ST131 producing extended spectrum β-lactamases (ESBLs) in a long-term care facility (LTCF) in Ireland by combining data from this LTCF (n=69) with other Irish (n=35) and global (n=690) ST131 genomes to reconstruct the evolutionary history and understand changes in population structure and genome architecture over time. [2]本研究包括产生超广谱β-内酰胺酶（ESBL）和碳青霉烯酶（KPC-2和NDM-1）的耐药菌，以及表现出对粘菌素耐药（mcr-1）和替加环素的耐药菌。 [1] 通过将来自该 LTCF (n=69) 的数据与其他爱尔兰 (n=35) 和全球 (n=690) ST131 的数据相结合，在爱尔兰的一家长期护理机构 (LTCF) 中产生超广谱 β-内酰胺酶 (ESBL) 的大肠杆菌 ST131基因组以重建进化历史并了解种群结构和基因组结构随时间的变化。 [2]